Immunogenicity of biologic agents in rheumatology von Strand, Vibeke, Goncalves, Joao, Isaacs, John D.

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Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis von Penkava, Frank, Velasco-Herrera, Martin Del Castillo, Young, Matthew D., Yager, Nicole, Nwosu, Lilian N., Pratt, Arthur G., Lara, Alicia Lledo, Guzzo, Charlotte, Maroof, Ash, Mamanova, Lira, Cole, Suzanne, Efremova, Mirjana, Simone, Davide, Filer, Andrew, Brown, Chrysothemis C., Croxford, Andrew L., Isaacs, John D., Teichmann, Sarah, Bowness, Paul, Behjati, Sam, Hussein Al-Mossawi, M.

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Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis von Bennett, Joshua L., Pratt, Arthur G., Dodds, Richard, Sayer, Avan A., Isaacs, John D.

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Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities von Mehta, Puja, Porter, Joanna C, Manson, Jessica J, Isaacs, John D, Openshaw, Peter J M, McInnes, Iain B, Summers, Charlotte, Chambers, Rachel C

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Integrated safety in tocilizumab clinical trials von Schiff, Michael H, Kremer, Joel M, Jahreis, Angelika, Vernon, Emma, Isaacs, John D, van Vollenhoven, Ronald F

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Differential properties of Janus kinase inhibitors in the treatment of immune-mediated inflammatory diseases von Taylor, Peter C, Choy, Ernest, Baraliakos, Xenofon, Szekanecz, Zoltan, Xavier, Ricardo M, Isaacs, John D, Strengholt, Sander, Parmentier, Julie M, Lippe, Ralph, Tanaka, Yoshiya

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Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to a... von Mathews, Rebeccah J, Robinson, James I, Battellino, Michele, Wong, Chi, Taylor, John C, Eyre, Steve, Churchman, Sarah M, Wilson, Anthony G, Isaacs, John D, Hyrich, Kimme, Barton, Anne, Plant, Darren, Savic, Sinisa, Cook, Graham P, Sarzi-Puttini, Piercarlo, Emery, Paul, Barrett, Jennifer H, Morgan, Ann W, McDermott, Michael F

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The changing face of rheumatoid arthritis: sustained remission for all? von Isaacs, John D.

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Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial... von Al-Laith, Mariam, Jasenecova, Marianna, Abraham, Sonya, Bosworth, Aisla, Bruce, Ian N, Buckley, Christopher D, Ciurtin, Coziana, D'Agostino, Maria-Antonietta, Emery, Paul, Gaston, Hill, Isaacs, John D, Filer, Andrew, Fisher, Benjamin A, Huizinga, Thomas W J, Ho, Pauline, Jacklin, Clare, Lempp, Heidi, McInnes, Iain B, Pratt, Arthur G, Östor, Andrew, Raza, Karim, Taylor, Peter C, van Schaardenburg, Dirkjan, Shivapatham, Dharshene, Wright, Alison J, Vasconcelos, Joana C, Kelly, Joanna, Murphy, Caroline, Prevost, A Toby, Cope, Andrew P

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Biologic therapies in rheumatology: lessons learned, future directions von Strand, Vibeke, Kimberly, Robert, Isaacs, John D.

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Predicting drug-free remission in rheumatoid arthritis: A prospective interventional cohort study von Baker, Kenneth F., Skelton, Andrew J., Lendrem, Dennis W., Scadeng, Adam, Thompson, Ben, Pratt, Arthur G., Isaacs, John D.

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Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission von Baker, Kenneth F., McDonald, David, Hulme, Gillian, Hussain, Rafiqul, Coxhead, Jonathan, Swan, David, Schulz, Axel R., Mei, Henrik E., MacDonald, Lucy, Pratt, Arthur G., Filby, Andrew, Anderson, Amy E., Isaacs, John D.

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The role of biosimilars in the treatment of rheumatic diseases von Dörner, Thomas, Strand, Vibeke, Castañeda-Hernández, Gilberto, Ferraccioli, Gianfranco, Isaacs, John D, Kvien, Tore K, Martin-Mola, Emilio, Mittendorf, Thomas, Smolen, Josef S, Burmester, Gerd R

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Seronegative rheumatoid arthritis: Pathogenetic and therapeutic aspects von Pratt, Arthur G, Isaacs, John D

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CAR T Cells — A New Horizon for Autoimmunity? von Isaacs, John D.

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Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells von Haniffa, Muzlifah A, Wang, Xiao-Nong, Holtick, Udo, Rae, Michelle, Isaacs, John D, Dickinson, Anne M, Hilkens, Catharien M. U, Collin, Matthew P

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Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study von Gault, Abigail, Hogarth, Linda, Williams, Kristian C, Greystoke, Alastair, Rajan, Neil, Speight, Ally, Lamb, Christopher A, Bridgewood, Alison, Brown-Schofield, Lisa-Jayne, Rayner, Fiona, Isaacs, John D, Nsengimana, Jérémie, Stewart, Christopher J, Anderson, Amy E, Plummer, Ruth, Pratt, Arthur G

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Anti-TNF therapy von Thalayasingam, Nishanthi, MA, BM BCh, Isaacs, John D., BSc (hon), MB BS, PhD, FRCP

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Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients von Wood, Matthew J, Leckenby, Adam, Reynolds, Gary, Spiering, Rachel, Pratt, Arthur G, Rankin, Kenneth S, Isaacs, John D, Haniffa, Muzlifah A, Milling, Simon, Hilkens, Catharien Mu

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LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells von Anderson, Amy E., Swan, David J., Sayers, Bethan L., Harry, Rachel A., Patterson, Angela M., Delwig, Alexei, Robinson, John H., Isaacs, John D., Hilkens, Catharien M. U.

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