A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies von Lehne, Benjamin, Drong, Alexander W, Loh, Marie, Zhang, Weihua, Scott, William R, Tan, Sian-Tsung, Afzal, Uzma, Scott, James, Jarvelin, Marjo-Riitta, Elliott, Paul, McCarthy, Mark I, Kooner, Jaspal S, Chambers, John C

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Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study von De Silva, N Maneka G, Borges, Maria Carolina, Hingorani, Aroon D, Engmann, Jorgen, Shah, Tina, Zhang, Xiaoshuai, Luan, Jian'an, Langenberg, Claudia, Wong, Andrew, Kuh, Diana, Chambers, John C, Zhang, Weihua, Jarvelin, Marjo-Ritta, Sebert, Sylvain, Auvinen, Juha, Gaunt, Tom R, Lawlor, Deborah A

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Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment von Sen-Chowdhry, Srijita, Morgan, Robert D, Chambers, John C, McKenna, William J

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Contribution of lower physical activity levels to higher risk of insulin resistance and associated metabolic disturbances in South Asians compared to Europeans von Afaq, Saima, Kooner, Angad S, Loh, Marie, Kooner, Jaspal S, Chambers, John C

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Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics von Tynkkynen, Tuulia, Wang, Qin, Ekholm, Jussi, Anufrieva, Olga, Ohukainen, Pauli, Vepsäläinen, Jouko, Männikkö, Minna, Keinänen-Kiukaanniemi, Sirkka, Holmes, Michael V, Goodwin, Matthew, Ring, Susan, Chambers, John C, Kooner, Jaspal, Järvelin, Marjo-Riitta, Kettunen, Johannes, Hill, Michael, Davey Smith, George, Ala-Korpela, Mika

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Population-Based Reference Values for 3D Echocardiographic LV Volumes and Ejection Fraction von Chahal, Navtej S., MD, Lim, Tiong K., MD, Jain, Piyush, MD, Chambers, John C., MD, Kooner, Jaspal S., MD, Senior, Roxy, MD

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Smokeless and combustible tobacco use among 148,944 South Asian adults: a cross-sectional study of South Asia Biobank von Xie, Wubin, Mridha, Malay Kanti, Gupta, Anaya, Kusuma, Dian, Butt, Awais Muhammad, Hasan, Mehedi, Brage, Soren, Loh, Marie, Khawaja, Khadija Irfan, Pradeepa, Rajendra, Jha, Vinita, Kasturiratne, Anuradhani, Katulanda, Prasad, Anjana, Ranjit Mohan, Chambers, John C

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A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides von Braun, Timothy R, Been, Latonya F, Singhal, Akhil, Worsham, Jacob, Ralhan, Sarju, Wander, Gurpreet S, Chambers, John C, Kooner, Jaspal S, Aston, Christopher E, Sanghera, Dharambir K

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The South Asian genome von Chambers, John C, Abbott, James, Zhang, Weihua, Turro, Ernest, Scott, William R, Tan, Sian-Tsung, Afzal, Uzma, Afaq, Saima, Loh, Marie, Lehne, Benjamin, O'Reilly, Paul, Gaulton, Kyle J, Pearson, Richard D, Li, Xinzhong, Lavery, Anita, Vandrovcova, Jana, Wass, Mark N, Miller, Kathryn, Sehmi, Joban, Oozageer, Laticia, Kooner, Ishminder K, Al-Hussaini, Abtehale, Mills, Rebecca, Grewal, Jagvir, Panoulas, Vasileios, Lewin, Alexandra M, Northwood, Korrinne, Wander, Gurpreet S, Geoghegan, Frank, Li, Yingrui, Wang, Jun, Aitman, Timothy J, McCarthy, Mark I, Scott, James, Butcher, Sarah, Elliott, Paul, Kooner, Jaspal S

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Common Genetic Variation Near Melatonin Receptor MTNR1B Contributes to Raised Plasma Glucose and Increased Risk of Type 2 Diabetes Among Indian Asians and European Caucasians von CHAMBERS, John C, WEIHUA ZHANG, SCOTT, James, ELLIOTT, Paul, KOONER, Jaspal S, ZABANEH, Delilah, SEHMI, Joban, JAIN, Piyush, MCCARTHY, Mark I, FROGUEL, Philippe, RUOKONEN, Aimo, BALDING, David, JARVELIN, Marjo-Riitta

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Investigation of Genetic Variation Underlying Central Obesity amongst South Asians von Scott, William R, Zhang, Weihua, Loh, Marie, Tan, Sian-Tsung, Lehne, Benjamin, Afzal, Uzma, Peralta, Juan, Saxena, Richa, Ralhan, Sarju, Wander, Gurpreet S, Bozaoglu, Kiymet, Sanghera, Dharambir K, Elliott, Paul, Scott, James, Chambers, John C, Kooner, Jaspal S

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Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies von Wang, Xu, Chua, Hui-Xiang, Chen, Peng, Ong, Rick Twee-Hee, Sim, Xueling, Zhang, Weihua, Takeuchi, Fumihiko, Liu, Xuanyao, Khor, Chiea-Chuen, Tay, Wan-Ting, Cheng, Ching-Yu, Suo, Chen, Liu, Jianjun, Aung, Tin, Chia, Kee-Seng, Kooner, Jaspal S, Chambers, John C, Wong, Tien-Yin, Tai, E-Shyong, Kato, Norihiro, Teo, Yik-Ying

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Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci von Paul, Dirk S, Albers, Cornelis A, Rendon, Augusto, Voss, Katrin, Stephens, Jonathan, van der Harst, Pim, Chambers, John C, Soranzo, Nicole, Ouwehand, Willem H, Deloukas, Panos

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A genomic mutational constraint map using variation in 76,156 human genomes von Chen, Siwei, Francioli, Laurent C., Goodrich, Julia K., Collins, Ryan L., Kanai, Masahiro, Wang, Qingbo, Alföldi, Jessica, Watts, Nicholas A., Vittal, Christopher, Gauthier, Laura D., Poterba, Timothy, Wilson, Michael W., Tarasova, Yekaterina, Phu, William, Grant, Riley, Yohannes, Mary T., Koenig, Zan, Farjoun, Yossi, Banks, Eric, Donnelly, Stacey, Gabriel, Stacey, Gupta, Namrata, Ferriera, Steven, Tolonen, Charlotte, Novod, Sam, Bergelson, Louis, Roazen, David, Ruano-Rubio, Valentin, Covarrubias, Miguel, Llanwarne, Christopher, Petrillo, Nikelle, Wade, Gordon, Jeandet, Thibault, Munshi, Ruchi, Tibbetts, Kathleen, O’Donnell-Luria, Anne, Solomonson, Matthew, Seed, Cotton, Martin, Alicia R., Talkowski, Michael E., Rehm, Heidi L., Daly, Mark J., Tiao, Grace, Neale, Benjamin M., MacArthur, Daniel G., Karczewski, Konrad J.

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Food environments and obesity: A geospatial analysis of the South Asia Biobank, income and sex inequalities von Atanasova, Petya, Kusuma, Dian, Pineda, Elisa, Anjana, Ranjit Mohan, De Silva, Laksara, Hanif, Abu A.M., Hasan, Mehedi, Hossain, Md Mokbul, Indrawansa, Susantha, Jayamanne, Deepal, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I., Kumarendran, Balachandran, Mridha, Malay K., Rajakaruna, Vindya, Chambers, John C., Frost, Gary, Sassi, Franco, Miraldo, Marisa

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The iHealth-T2D study: a cluster randomised trial for the prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes-a statistical analysis plan von Muilwijk, Mirthe, Loh, Marie, Mahmood, Sara, Palaniswamy, Saranya, Siddiqui, Samreen, Silva, Wnurinham, Frost, Gary S, Gage, Heather M, Jarvelin, Marjo-Riitta, Rannan-Eliya, Ravindra P, Ahmad, Sajjad, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I, Kooner, Jaspal S, Wickremasinghe, Ananda R, van Valkengoed, Irene G M, Chambers, John C

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Translational Perspective on Epigenetics in Cardiovascular Disease von van der Harst, Pim, de Windt, Leon J., Chambers, John C.

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Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men von Chambers, John C, Obeid, Omar A, Refsum, Helga, Ueland, Per, Hackett, David, Hooper, James, Turner, Rebecca M, Thompson, Slmon G, Kooner, Jaspal S

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Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study von Cardona, Alexia, Day, Felix R, Perry, John R B, Loh, Marie, Chu, Audrey Y, Lehne, Benjamin, Paul, Dirk S, Lotta, Luca A, Stewart, Isobel D, Kerrison, Nicola D, Scott, Robert A, Khaw, Kay-Tee, Forouhi, Nita G, Langenberg, Claudia, Liu, Chunyu, Mendelson, Michael M, Levy, Daniel, Beck, Stephan, Leslie, R David, Dupuis, Josée, Meigs, James B, Kooner, Jaspal S, Pihlajamäki, Jussi, Vaag, Allan, Perfilyev, Alexander, Ling, Charlotte, Hivert, Marie-France, Chambers, John C, Wareham, Nicholas J, Ong, Ken K

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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function von Hawe, Johann S., Wilson, Rory, Schmid, Katharina T., Zhou, Li, Lakshmanan, Lakshmi Narayanan, Lehne, Benjamin C., Kühnel, Brigitte, Scott, William R., Wielscher, Matthias, Yew, Yik Weng, Baumbach, Clemens, Lee, Dominic P., Marouli, Eirini, Bernard, Manon, Pfeiffer, Liliane, Matías-García, Pamela R., Autio, Matias I., Bourgeois, Stephane, Herder, Christian, Karhunen, Ville, Meitinger, Thomas, Prokisch, Holger, Rathmann, Wolfgang, Roden, Michael, Sebert, Sylvain, Shin, Jean, Strauch, Konstantin, Zhang, Weihua, Tan, Wilson L. W., Hauck, Stefanie M., Merl-Pham, Juliane, Grallert, Harald, Barbosa, Eudes G. V., Illig, Thomas, Peters, Annette, Paus, Tomas, Pausova, Zdenka, Deloukas, Panos, Foo, Roger S. Y., Jarvelin, Marjo-Riitta, Kooner, Jaspal S., Loh, Marie, Heinig, Matthias, Gieger, Christian, Waldenberger, Melanie, Chambers, John C.

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