Defining the landscape of ATP-competitive inhibitor resistance residues in protein kinases von Persky, N. S., Hernandez, D., Do Carmo, M., Brenan, L., Cohen, O., Kitajima, S., Nayar, U., Walker, A., Pantel, S., Lee, Y., Cordova, J., Sathappa, M., Zhu, C., Hayes, T. K., Ram, P., Pancholi, P., Mikkelsen, T. S., Barbie, D. A., Yang, X., Haq, R., Piccioni, F., Root, D. E., Johannessen, C. M.

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REDD1, a Developmentally Regulated Transcriptional Target of p63 and p53, Links p63 to Regulation of Reactive Oxygen Species von Ellisen, Leif W, Ramsayer, Kate D, Johannessen, Cory M, Yang, Annie, Beppu, Hideyuki, Minda, Karolina, Oliner, Jonathan D, McKeon, Frank, Haber, Daniel A

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Characterizing genomic alterations in cancer by complementary functional associations von Kim, Jong Wook, Botvinnik, Olga B, Abudayyeh, Omar, Birger, Chet, Rosenbluh, Joseph, Shrestha, Yashaswi, Abazeed, Mohamed E, Hammerman, Peter S, DiCara, Daniel, Konieczkowski, David J, Johannessen, Cory M, Liberzon, Arthur, Alizad-Rahvar, Amir Reza, Alexe, Gabriela, Aguirre, Andrew, Ghandi, Mahmoud, Greulich, Heidi, Vazquez, Francisca, Weir, Barbara A, Van Allen, Eliezer M, Tsherniak, Aviad, Shao, Diane D, Zack, Travis I, Noble, Michael, Getz, Gad, Beroukhim, Rameen, Garraway, Levi A, Ardakani, Masoud, Romualdi, Chiara, Sales, Gabriele, Barbie, David A, Boehm, Jesse S, Hahn, William C, Mesirov, Jill P, Tamayo, Pablo

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TORC1 Is Essential for NF1-Associated Malignancies von Johannessen, Cory M., Johnson, Bryan W., Williams, Sybil M. Genther, Chan, Annie W., Reczek, Elizabeth E., Lynch, Ryan C., Rioth, Matthew J., McClatchey, Andrea, Ryeom, Sandra, Cichowski, Karen

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Regulation of mTOR and Cell Growth in Response to Energy Stress by REDD1 von Sofer, Avi, Lei, Kui, Johannessen, Cory M., Ellisen, Leif W.

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The NF1 Tumor Suppressor Critically Regulates TSC2 and mTOR von Johannessen, Cory M., Reczek, Elizabeth E., James, Marianne F., Brems, Hilde, Legius, Eric, Cichowski, Karen, Cantley, Lewis C.

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Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study von Nilsson, Sten, Prof, Franzén, Lars, MD, Parker, Christopher, Dr, Tyrrell, Christopher, FRCR, Blom, René, MD, Tennvall, Jan, Prof, Lennernäs, Bo, MD, Petersson, Ulf, MD, Johannessen, Dag C, MD, Sokal, Michael, FRCR, Pigott, Katharine, FRCR, Yachnin, Jeffrey, MD, Garkavij, Michael, MD, Strang, Peter, Prof, Harmenberg, Johan, MD, Bolstad, Bjørg, MSc, Bruland, Øyvind S, Prof

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MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma von Wood, Kris C, Konieczkowski, David J, Johannessen, Cory M, Boehm, Jesse S, Tamayo, Pablo, Botvinnik, Olga B, Mesirov, Jill P, Hahn, William C, Root, David E, Garraway, Levi A, Sabatini, David M

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Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine von Howard, Thomas P., Oberlick, Elaine M., Rees, Matthew G., Arnoff, Taylor E., Minh-Tam Pham, Brenan, Lisa, DoCarmo, Mariana, Hong, Andrew L., Kugener, Guillaume, Chou, Hsien-Chao, Drosos, Yiannis, Mathias, Kaeli M., Ramos, Pilar, Seashore-Ludlow, Brinton, Giacomelli, Andrew O., Wang, Xiaofeng, Freeman, Burgess B., Blankenship, Kaley, Hoffmann, Lauren, Tiv, Hong L., Gokhale, Prafulla C., Johannessen, Cory M., Stewart, Elizabeth A., Schreiber, Stuart L., Hahn, William C., Roberts, Charles W. M.

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Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery von Johannessen, Cory M, Clemons, Paul A, Wagner, Bridget K

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Characterizing genomic alterations in cancer by complementary functional associations von Kim, J. W, Botvinnik, O. B, Abudayyeh, O, Birger, C, Rosenbluh, J, Shrestha, Y, Abazeed, M. E, Hammerman, P. S, DiCara, D, Konieczkowski, D. J, Johannessen, C. M, Liberzon, A, Alizad-Rahvar, A. R, Alexe, G, Aguirre, A, Ghandi, M, Greulich, H, Vazquez, F, Weir, B. A, Van Allen, E. M, Tsherniak, A, Shao, D. D, Zack, T. I, Noble, M, Getz, G, Beroukhim, R, Garraway, L. A, Ardakani, M, Romualdi, C, Sales, G, Barbie, D. A, Boehm, J. S, Hahn, W. C, Mesirov, J. P, Tamayo, P

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation von Johannessen, C M, Boehm, J S, Kim, S Y, Thomas, S R, Wardwell, L, Johnson, L A, Emery, C M, Stransky, N, Cogdill, A P, Barretina, J, Caponigro, G, Hieronymus, H, Murray, R R, Salehi-Ashtiani, K, Hill, D E, Vidal, M, Zhao, J J, Yang, X, Alkan, O, Kim, S, Harris, J L, Wilson, C J, Myer, V E, Finan, P M, Root, D E, Roberts, T M, Golub, T, Flaherty, K T, Dummer, R, Weber, B L, Sellers, W R, Schlegel, R, Wargo, J A, Hahn, W C, Garraway, L A

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Alpha Emitter Radium-223 and Survival in Metastatic Prostate Cancer von Parker, C, Nilsson, S, Heinrich, D, Helle, S.I, O'Sullivan, J.M, Fosså, S.D, Chodacki, A, Wiechno, P, Logue, J, Seke, M, Widmark, A, Johannessen, D.C, Hoskin, P, Bottomley, D, James, N.D, Solberg, A, Syndikus, I, Kliment, J, Wedel, S, Boehmer, S, Dall'Oglio, M, Franzén, L, Coleman, R, Vogelzang, N.J, O'Bryan-Tear, C.G, Staudacher, K, Garcia-Vargas, J, Shan, M, Bruland, Ø.S, Sartor, O

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Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines von Reimers, Arne, Berg, Jon Andsnes, Burns, Margrete Larsen, Brodtkorb, Eylert, Johannessen, Svein I, Johannessen Landmark, Cecilie

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The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results von Johannessen Landmark, Cecilie, Potschka, Heidrun, Auvin, Stéphane, Wilmshurst, Jo M., Johannessen, Svein I., Kasteleijn‐Nolst Trenité, Dorothée, Wirrell, Elaine C.

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Oncological outcomes of standard versus prolonged time to surgery after neoadjuvant chemoradiotherapy for oesophageal cancer in the multicentre, randomised, controlled NeoRes II tr... von Nilsson, K., Klevebro, F., Sunde, B., Rouvelas, I., Lindblad, M., Szabo, E., Halldestam, I., Smedh, U., Wallner, B., Johansson, J., Johnsen, G., Aahlin, E.K., Johannessen, H.-O., Alexandersson von Döbeln, G., Hjortland, G.O., Wang, N., Shang, Y., Borg, D., Quaas, A., Bartella, I., Bruns, C., Schröder, W., Nilsson, M.

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Mutational processes shape the landscape of TP53 mutations in human cancer von Giacomelli, Andrew O., Yang, Xiaoping, Lintner, Robert E., McFarland, James M., Duby, Marc, Kim, Jaegil, Howard, Thomas P., Takeda, David Y., Ly, Seav Huong, Kim, Eejung, Gannon, Hugh S., Hurhula, Brian, Sharpe, Ted, Goodale, Amy, Fritchman, Briana, Steelman, Scott, Vazquez, Francisca, Tsherniak, Aviad, Aguirre, Andrew J., Doench, John G., Piccioni, Federica, Roberts, Charles W. M., Meyerson, Matthew, Getz, Gad, Johannessen, Cory M., Root, David E., Hahn, William C.

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A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer von Wilson, Frederick H., Johannessen, Cory M., Piccioni, Federica, Tamayo, Pablo, Kim, Jong Wook, Van Allen, Eliezer M., Corsello, Steven M., Capelletti, Marzia, Calles, Antonio, Butaney, Mohit, Sharifnia, Tanaz, Gabriel, Stacey B., Mesirov, Jill P., Hahn, William C., Engelman, Jeffrey A., Meyerson, Matthew, Root, David E., Jänne, Pasi A., Garraway, Levi A.

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Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling von WAGLE, Nikhil, EMERY, Caroline, MEYERSON, Matthew, GARRAWAY, Levi A, BERGER, Michael F, DAVIS, Matthew J, SAWYER, Allison, POCHANARD, Panisa, KEHOE, Sarah M, JOHANNESSEN, Cory M, MACCONAILL, Laura E, HAHN, William C

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The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma von Van Allen, Eliezer M, Wagle, Nikhil, Sucker, Antje, Treacy, Daniel J, Johannessen, Cory M, Goetz, Eva M, Place, Chelsea S, Taylor-Weiner, Amaro, Whittaker, Steven, Kryukov, Gregory V, Hodis, Eran, Rosenberg, Mara, McKenna, Aaron, Cibulskis, Kristian, Farlow, Deborah, Zimmer, Lisa, Hillen, Uwe, Gutzmer, Ralf, Goldinger, Simone M, Ugurel, Selma, Gogas, Helen J, Egberts, Friederike, Berking, Carola, Trefzer, Uwe, Loquai, Carmen, Weide, Benjamin, Hassel, Jessica C, Gabriel, Stacey B, Carter, Scott L, Getz, Gad, Garraway, Levi A, Schadendorf, Dirk

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