Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort von Org, Elin, Blum, Yuna, Kasela, Silva, Mehrabian, Margarete, Kuusisto, Johanna, Kangas, Antti J, Soininen, Pasi, Wang, Zeneng, Ala-Korpela, Mika, Hazen, Stanley L, Laakso, Markku, Lusis, Aldons J

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The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases von Laakso, Markku, Kuusisto, Johanna, Stančáková, Alena, Kuulasmaa, Teemu, Pajukanta, Päivi, Lusis, Aldons J., Collins, Francis S., Mohlke, Karen L., Boehnke, Michael

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Lipidome as a predictive tool in progression to type 2 diabetes in Finnish men von Suvitaival, Tommi, Bondia-Pons, Isabel, Yetukuri, Laxman, Pöhö, Päivi, Nolan, John J., Hyötyläinen, Tuulia, Kuusisto, Johanna, Orešič, Matej

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Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences von Spracklen, Cassandra N, Iyengar, Apoorva K, Vadlamudi, Swarooparani, Raulerson, Chelsea K, Jackson, Anne U, Brotman, Sarah M, Wu, Ying, Cannon, Maren E, Davis, James P, Crain, Aaron T, Currin, Kevin W, Perrin, Hannah J, Narisu, Narisu, Stringham, Heather M, Fuchsberger, Christian, Locke, Adam E, Welch, Ryan P, Kuusisto, Johanna K, Pajukanta, Päivi, Scott, Laura J, Li, Yun, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L

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Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling von Koivumäki, Jussi T, Naumenko, Nikolay, Tuomainen, Tomi, Takalo, Jouni, Oksanen, Minna, Puttonen, Katja A, Lehtonen, Šárka, Kuusisto, Johanna, Laakso, Markku, Koistinaho, Jari, Tavi, Pasi

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Biomarkers reflecting insulin resistance increase the risk of aortic stenosis in a population-based study of 10,144 Finnish men von Sohlman, Maija, Jauhiainen, Raimo, Vangipurapu, Jagadish, Laakso, Annamaria, Ala-Korpela, Mika, Kuulasmaa, Teemu, Kuusisto, Johanna

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Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits von Civelek, Mete, Wu, Ying, Pan, Calvin, Raulerson, Chelsea K., Ko, Arthur, He, Aiqing, Tilford, Charles, Saleem, Niyas K., Stančáková, Alena, Scott, Laura J., Fuchsberger, Christian, Stringham, Heather M., Jackson, Anne U., Narisu, Narisu, Chines, Peter S., Small, Kerrin S., Kuusisto, Johanna, Parks, Brian W., Pajukanta, Päivi, Kirchgessner, Todd, Collins, Francis S., Gargalovic, Peter S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L., Lusis, Aldons J.

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Plasma fatty acids as predictors of glycaemia and type 2 diabetes von Lankinen, Maria A., Stančáková, Alena, Uusitupa, Matti, Ågren, Jyrki, Pihlajamäki, Jussi, Kuusisto, Johanna, Schwab, Ursula, Laakso, Markku

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Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men von STANCAKOVA, Alena, JAVORSKY, Martin, KUULASMAA, Teemu, HAFFNER, Steven M, KUUSISTO, Johanna, LAAKSO, Markku

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Genetics of hypertrophic cardiomyopathy: what is the next step? von Kuusisto, Johanna

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Both fasting and glucose-stimulated proinsulin levels predict hyperglycemia and incident type 2 diabetes: a population-based study of 9,396 Finnish men von Vangipurapu, Jagadish, Stančáková, Alena, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku

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Fatty acid metabolism is altered in non-alcoholic steatohepatitis independent of obesity von Walle, Paula, Takkunen, Markus, Männistö, Ville, Vaittinen, Maija, Lankinen, Maria, Kärjä, Vesa, Käkelä, Pirjo, Ågren, Jyrki, Tiainen, Mika, Schwab, Ursula, Kuusisto, Johanna, Laakso, Markku, Pihlajamäki, Jussi

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Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy von Kuusisto, Johanna, Kärjä, Vesa, Sipola, Petri, Kholová, Ivana, Peuhkurinen, Keijo, Jääskeläinen, Pertti, Naukkarinen, Anita, Ylä-Herttuala, Seppo, Punnonen, Kari, Laakso, Markku

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Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids von Fagerlund, Ilkka, Dougalis, Antonios, Shakirzyanova, Anastasia, Gómez-Budia, Mireia, Pelkonen, Anssi, Konttinen, Henna, Ohtonen, Sohvi, Fazaludeen, Mohammad Feroze, Koskuvi, Marja, Kuusisto, Johanna, Hernández, Damián, Pebay, Alice, Koistinaho, Jari, Rauramaa, Tuomas, Lehtonen, Šárka, Korhonen, Paula, Malm, Tarja

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Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells von Yaluri, Nagendra, Modi, Shalem, López Rodríguez, Maykel, Stančáková, Alena, Kuusisto, Johanna, Kokkola, Tarja, Laakso, Markku

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Finnish Diabetes Risk Score Is Associated with Impaired Insulin Secretion and Insulin Sensitivity, Drug-Treated Hypertension and Cardiovascular Disease: A Follow-Up Study of the ME... von Fizelova, Maria, Jauhiainen, Raimo, Stančáková, Alena, Kuusisto, Johanna, Laakso, Markku

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Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns von Kim, Daniel Seung, Jackson, Anne U., Li, Yatong K., Stringham, Heather M., Kuusisto, Johanna, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Burant, Charles F., Salomaa, Veikko, Boehnke, Michael, Laakso, Markku, Speliotes, Elizabeth K.

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Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men von Stancáková, Alena, Kuulasmaa, Teemu, Paananen, Jussi, Jackson, Anne U, Bonnycastle, Lori L, Collins, Francis S, Boehnke, Michael, Kuusisto, Johanna, Laakso, Markku

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A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus von Roman, Tamara S, Cannon, Maren E, Vadlamudi, Swarooparani, Buchkovich, Martin L, Wolford, Brooke N, Welch, Ryan P, Morken, Mario A, Kwon, Grace J, Varshney, Arushi, Kursawe, Romy, Wu, Ying, Jackson, Anne U, Erdos, Michael R, Kuusisto, Johanna, Laakso, Markku, Scott, Laura J, Boehnke, Michael, Collins, Francis S, Parker, Stephen C J, Stitzel, Michael L, Mohlke, Karen L

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Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans von Männistö, Ville T., Simonen, Marko, Hyysalo, Jenni, Soininen, Pasi, Kangas, Antti J., Kaminska, Dorota, Matte, Ananda K., Venesmaa, Sari, Käkelä, Pirjo, Kärjä, Vesa, Arola, Johanna, Gylling, Helena, Cederberg, Henna, Kuusisto, Johanna, Laakso, Markku, Yki-Järvinen, Hannele, Ala-Korpela, Mika, Pihlajamäki, Jussi

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