An optimized bioluminescent substrate for non-invasive imaging in the brain von Su, Yichi, Walker, Joel R., Hall, Mary P., Klein, Mark A., Wu, Xiang, Encell, Lance P., Casey, Kerriann M., Liu, Lan Xiang, Hong, Guosong, Lin, Michael Z., Kirkland, Thomas A.

Volltext

Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice von Gaspar, Natasa, Walker, Joel R., Zambito, Giorgia, Marella-Panth, Kranthi, Lowik, Clemens, Kirkland, Thomas A., Mezzanotte, Laura

Volltext

Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression von Carossino, Mariano, Kenney, Devin, O'Connell, Aoife K, Montanaro, Paige, Tseng, Anna E, Gertje, Hans P, Grosz, Kyle A, Ericsson, Maria, Huber, Bertrand R, Kurnick, Susanna A, Subramaniam, Saravanan, Kirkland, Thomas A, Walker, Joel R, Francis, Kevin P, Klose, Alexander D, Paragas, Neal, Bosmann, Markus, Saeed, Mohsan, Balasuriya, Udeni B R, Douam, Florian, Crossland, Nicholas A

Volltext

Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms von Grohmann, Christoph, Magtoto, Charlene M., Walker, Joel R., Chua, Ngee Kiat, Gabrielyan, Anna, Hall, Mary, Cobbold, Simon A., Mieruszynski, Stephen, Brzozowski, Martin, Simpson, Daniel S., Dong, Hao, Dorizzi, Bridget, Jacobsen, Annette V., Morrish, Emma, Silke, Natasha, Murphy, James M., Heath, Joan K., Testa, Andrea, Maniaci, Chiara, Ciulli, Alessio, Lessene, Guillaume, Silke, John, Feltham, Rebecca

Volltext

Optogenetic Control of Non‐Apoptotic Cell Death von He, Lian, Huang, Zixian, Huang, Kai, Chen, Rui, Nguyen, Nhung T., Wang, Rui, Cai, Xiaoli, Huang, Zhiquan, Siwko, Stefan, Walker, Joel R., Han, Gang, Zhou, Yubin, Jing, Ji

Volltext

NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform von Gaspar, Natasa, Zambito, Giorgia, Dautzenberg, Iris J C, Cramer, Steve J, Hoeben, Rob C, Lowik, Clemens, Walker, Joel R, Kirkland, Thomas A, Smith, Thomas P, van Weerden, Wytske M, de Vrij, Jeroen, Mezzanotte, Laura

Volltext

Optimized in vivo multispectral bioluminescent imaging of tumor biology using engineered BRET reporters von Labra, Bryan, Parag-Sharma, Kshitij, Powers, John J., Srivastava, Sonal, Walker, Joel R., Kirkland, Thomas A., Brennan, Caroline K., Prescher, Jennifer A., Amelio, Antonio L.

Volltext

Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals von Su, Yichi, Walker, Joel R., Park, Yunhee, Smith, Thomas P., Liu, Lan Xiang, Hall, Mary P., Labanieh, Louai, Hurst, Robin, Wang, David C., Encell, Lance P., Kim, Namdoo, Zhang, Feijie, Kay, Mark A., Casey, Kerriann M., Majzner, Robbie G., Cochran, Jennifer R., Mackall, Crystal L., Kirkland, Thomas A., Lin, Michael Z.

Volltext

Machine Learning Opportunities in Flight Test: Preflight Checks von Walker, Joel R., Claudio, David

Volltext

In Vitro and In Vivo Analysis of Extracellular Vesicle‐Mediated Metastasis Using a Bright, Red‐Shifted Bioluminescent Reporter Protein von Perez, Gloria I., Broadbent, David, Zarea, Ahmed A., Dolgikh, Benedikt, Bernard, Matthew P., Withrow, Alicia, McGill, Amelia, Toomajian, Victoria, Thampy, Lukose K., Harkema, Jack, Walker, Joel R., Kirkland, Thomas A., Bachmann, Michael H., Schmidt, Jens, Kanada, Masamitsu

Volltext

Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders von Gurney, Mark E, Nugent, Richard A, Mo, Xuesheng, Sindac, Janice A, Hagen, Timothy J, Fox, David, O’Donnell, James M, Zhang, Chong, Xu, Ying, Zhang, Han-Ting, Groppi, Vincent E, Bailie, Marc, White, Ronald E, Romero, Donna L, Vellekoop, A. Samuel, Walker, Joel R, Surman, Matthew D, Zhu, Lei, Campbell, Robert F

Volltext

Kinase-Modulated Bioluminescent Indicators Enable Noninvasive Imaging of Drug Activity in the Brain von Wu, Yan, Walker, Joel R., Westberg, Michael, Ning, Lin, Monje, Michelle, Kirkland, Thomas A., Lin, Michael Z., Su, Yichi

Volltext

Coelenterazine analogues emit red-shifted bioluminescence with NanoLuc von Shakhmin, Anton, Hall, Mary P, Machleidt, Thomas, Walker, Joel R, Wood, Keith V, Kirkland, Thomas A

Volltext

Three Efficient Methods for Preparation of Coelenterazine Analogues von Shakhmin, Anton, Hall, Mary P., Walker, Joel R., Machleidt, Thomas, Binkowski, Brock F., Wood, Keith V., Kirkland, Thomas A.

Volltext

Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide von Walker, Joel R., Alshafie, Galal, Nieves, Nirca, Ahrens, Jamie, Clagett-Dame, Margaret, Abou-Issa, Hussein, Curley, Robert W.

Volltext

Synthesis of isoindolinones via inverse-electron demand Diels–Alder cycloadditions von Huntley, Raymond J., Gurram, Mahender, Walker, Joel R., Jenkins, David M., Robé, Emmanuel J., Ahmed, Feryan

Volltext

Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors von Walker, Joel R, Hall, Mary P, Zimprich, Chad A, Robers, Matthew B, Duellman, Sarah J, Machleidt, Thomas, Rodriguez, Jacquelynn, Zhou, Wenhui

Volltext

Type-2 Isopentenyl Diphosphate Isomerase. Mechanistic Studies with Cyclopropyl and Epoxy Analogues von Johnston, Jonathan B., Walker, Joel R., Rothman, Steven C., Poulter, C. Dale

Volltext

Synthesis and Evaluation of Substrate Analogues as Mechanism-Based Inhibitors of Type II Isopentenyl Diphosphate Isomerase von Walker, Joel R, Rothman, Steven C, Poulter, C. Dale

Volltext

Inhibition of Mammary Tumor Growth by a Novel Nontoxic Retinoid: Chemotherapeutic Evaluation of a C-Linked Analog of 4-HPR-Glucuronide von ALSHAFIE, Galal A, WALKER, Joel R, CURLEY, Robert W, CLAGETT-DAME, Margaret, HIGHLAND, Margaret A, NIEVES, Nirca J, STONEROCK, Laura A, ABOU-ISSA, Hussein

Volltext