Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis von Saini, Vikram, Cumming, Bridgette M., Guidry, Loni, Lamprecht, Dirk A., Adamson, John H., Reddy, Vineel P., Chinta, Krishna C., Mazorodze, James H., Glasgow, Joel N., Richard-Greenblatt, Melissa, Gomez-Velasco, Anaximandro, Bach, Horacio, Av-Gay, Yossef, Eoh, Hyungjin, Rhee, Kyu, Steyn, Adrie J.C.

Volltext

Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis von Saini, Vikram, Chinta, Krishna C., Reddy, Vineel P., Glasgow, Joel N., Stein, Asaf, Lamprecht, Dirk A., Rahman, Md. Aejazur, Mackenzie, Jared S., Truebody, Barry E., Adamson, John H., Kunota, Tafara T. R., Bailey, Shannon M., Moellering, Douglas R., Lancaster, Jack R., Steyn, Adrie J. C.

Volltext

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis von Mackenzie, Jared S., Lamprecht, Dirk A., Asmal, Rukaya, Adamson, John H., Borah, Khushboo, Beste, Dany J. V., Lee, Bei Shi, Pethe, Kevin, Rousseau, Simon, Krieger, Inna, Sacchettini, James C., Glasgow, Joel N., Steyn, Adrie J. C.

Volltext

NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis von Pacl, Hayden T., Chinta, Krishna C., Reddy, Vineel P., Nadeem, Sajid, Sevalkar, Ritesh R., Nargan, Kievershen, Lumamba, Kapongo, Naidoo, Threnesan, Glasgow, Joel N., Agarwal, Anupam, Steyn, Adrie J. C.

Volltext

Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection von Reddy, Vineel P, Chinta, Krishna C, Saini, Vikram, Glasgow, Joel N, Hull, Travis D, Traylor, Amie, Rey-Stolle, Fernanda, Soares, Miguel P, Madansein, Rajhmun, Rahman, Md Aejazur, Barbas, Coral, Nargan, Kievershen, Naidoo, Threnesan, Ramdial, Pratistadevi K, George, James F, Agarwal, Anupam, Steyn, Adrie J C

Volltext

The Role of Host-Generated H2S in Microbial Pathogenesis: New Perspectives on Tuberculosis von Rahman, Md. Aejazur, Glasgow, Joel N., Nadeem, Sajid, Reddy, Vineel P., Sevalkar, Ritesh R., Lancaster, Jack R., Steyn, Adrie J. C.

Volltext

A high‐resolution 3D atlas of the spectrum of tuberculous and COVID‐19 lung lesions von Wells, Gordon, Glasgow, Joel N, Nargan, Kievershen, Lumamba, Kapongo, Madansein, Rajhmun, Maharaj, Kameel, Perumal, Leon Y, Matthew, Malcolm, Hunter, Robert L, Pacl, Hayden, Peabody Lever, Jacelyn E, Stanford, Denise D, Singh, Satinder P, Bajpai, Prachi, Manne, Upender, Benson, Paul V, Rowe, Steven M, le Roux, Stephan, Sigal, Alex, Tshibalanganda, Muofhe, Wells, Carlyn, du Plessis, Anton, Msimang, Mpumelelo, Naidoo, Threnesan, Steyn, Adrie J C

Volltext

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis von Chinta, Krishna C., Rahman, Md. Aejazur, Saini, Vikram, Glasgow, Joel N., Reddy, Vineel P., Lever, Jeremie M., Nhamoyebonde, Shepherd, Leslie, Alasdair, Wells, Ryan M., Traylor, Amie, Madansein, Rajhmun, Siegal, Gene P., Antony, Veena B., Deshane, Jessy, Wells, Gordon, Nargan, Kievershen, George, James F., Ramdial, Pratistadevi K., Agarwal, Anupam, Steyn, Adrie J.C.

Volltext

LiLA: lipid lung-based ATLAS built through a comprehensive workflow designed for an accurate lipid annotation von Fernández Requena, Belén, Nadeem, Sajid, Reddy, Vineel P., Naidoo, Vanessa, Glasgow, Joel N., Steyn, Adrie J. C., Barbas, Coral, Gonzalez-Riano, Carolina

Volltext

Mycobacterium tuberculosis DosS binds H2S through its Fe3+ heme iron to regulate the DosR dormancy regulon von Sevalkar, Ritesh R., Glasgow, Joel N., Pettinati, Martín, Marti, Marcelo A., Reddy, Vineel P., Basu, Swati, Alipour, Elmira, Kim-Shapiro, Daniel B., Estrin, Dario A., Lancaster, Jack R., Steyn, Adrie J.C.

Volltext

Iron sulfur cluster proteins and microbial regulation: implications for understanding tuberculosis von Saini, Vikram, Farhana, Aisha, Glasgow, Joel N, Steyn, Adrie JC

Volltext

An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer von Kim, Julius W, Glasgow, Joel N, Nakayama, Masaharu, Ak, Ferhat, Ugai, Hideyo, Curiel, David T

Volltext

Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility von Kunota, Tafara T. R., Rahman, Md. Aejazur, Truebody, Barry E., Mackenzie, Jared S., Saini, Vikram, Lamprecht, Dirk A., Adamson, John H., Sevalkar, Ritesh R., Lancaster, Jack R., Berney, Michael, Glasgow, Joel N., Steyn, Adrie J. C.

Volltext

A strategy for adenovirus vector targeting with a secreted single chain antibody von Glasgow, Joel N, Mikheeva, Galina, Krasnykh, Victor, Curiel, David T

Volltext

Contrasting Effects of Human, Canine, and Hybrid Adenovirus Vectors on the Phenotypical and Functional Maturation of Human Dendritic Cells: Implications for Clinical Efficacy von PERREAU, Matthieu, MENNECHET, Franck, SERRATRICE, Nicolas, GLASGOW, Joel N, CURIEL, David T, WODRICH, Harald, KREMER, Eric J

Volltext

Micro-Computed Tomography Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in Three-dimensional Granuloma Morphology von Wells, Gordon, Glasgow, Joel N, Nargan, Kievershen, Lumamba, Kapongo, Madansein, Rajhmun, Maharaj, Kameel, Hunter, Robert L, Naidoo, Threnesan, Coetzer, Llelani, le Roux, Stephan, du Plessis, Anton, Steyn, Adrie J C

Volltext

Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy von Lewis, Travis B, Glasgow, Joel N, Harms, Ashley S, Standaert, David G, Curiel, David T

Volltext

A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration von van de Ven, Rieneke, Scheffer, George L., Reurs, Anneke W., Lindenberg, Jelle J., Oerlemans, Ruud, Jansen, Gerrit, Gillet, Jean-Pierre, Glasgow, Joel N., Pereboev, Alexander, Curiel, David T., Scheper, Rik J., de Gruijl, Tanja D.

Volltext

Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy von Lewis, Travis B, Glasgow, Joel N, Glandon, Anya M, Curiel, David T, Standaert, David G

Volltext

Crystallographic Structure of Porcine Adenovirus Type 4 Fiber Head and Galectin Domains von Guardado-Calvo, Pablo, Muñoz, Eva M, Llamas-Saiz, Antonio L, Fox, Gavin C, Kahn, Richard, Curiel, David T, Glasgow, Joel N, van Raaij, Mark J

Volltext