Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin von Whittle, James R. R, Zhang, Ruijun, Khurana, Surender, King, Lisa R, Manischewitz, Jody, Golding, Hana, Dormitzer, Philip R, Haynes, Barton F, Walter, Emmanuel B, Moody, M. Anthony, Kepler, Thomas B, Liao, Hua-Xin, Harrison, Stephen C

Volltext

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody von Schmidt, Aaron G., Xu, Huafeng, Khan, Amir R., O'Donnell, Timothy, Khurana, Surender, King, Lisa R., Manischewitz, Jody, Golding, Hana, Suphaphiphat, Pirada, Carfi, Andrea, Settembre, Ethan C., Dormitzer, Philip R., Kepler, Thomas B., Zhang, Ruijun, Moody, M. Anthony, Haynes, Barton F., Liao, Hua-Xin, Shaw, David E., Harrison, Stephen C.

Volltext

A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin von Yu, Fei, Song, He, Wu, Yanling, Chang, So Young, Wang, Lili, Li, Wei, Hong, Binbin, Xia, Shuai, Wang, Chunyu, Khurana, Surender, Feng, Yang, Wang, Yanping, Sun, Zhiwu, He, Biao, Hou, Dongni, Manischewitz, Jody, King, Lisa R., Song, Yuanlin, Min, Ji-Young, Golding, Hana, Ji, Xinhua, Lu, Lu, Jiang, Shibo, Dimitrov, Dimiter S., Ying, Tianlei

Volltext

H5N1 Virus-Like Particle Vaccine Elicits Cross-Reactive Neutralizing Antibodies That Preferentially Bind to the Oligomeric Form of Influenza Virus Hemagglutinin in Humans von KHURANA, Surender, JIAN WU, GLENN, Gregory, GOLDING, Hana, VERMA, Nitin, VERMA, Swati, RAGHUNANDAN, Ramadevi, MANISCHEWITZ, Jody, KING, Lisa R, KPAMEGAN, Eloi, PINCUS, Steven, SMITH, Gale

Volltext

Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets von Khurana, Surender, Suguitan, Jr, Amorsolo L, Rivera, Yonaira, Simmons, Cameron P, Lanzavecchia, Antonio, Sallusto, Federica, Manischewitz, Jody, King, Lisa R, Subbarao, Kanta, Golding, Hana

Volltext

Acute and persistent responses after H5N1 vaccination in humans von Apps, Richard, Biancotto, Angélique, Candia, Julián, Kotliarov, Yuri, Perl, Shira, Cheung, Foo, Farmer, Rohit, Mulè, Matthew P., Rachmaninoff, Nicholas, Chen, Jinguo, Martins, Andrew J., Shi, Rongye, Zhou, Huizhi, Bansal, Neha, Schum, Paula, Olnes, Matthew J., Milanez-Almeida, Pedro, Han, Kyu Lee, Sellers, Brian, Cortese, Mario, Hagan, Thomas, Rouphael, Nadine, Pulendran, Bali, King, Lisa, Manischewitz, Jody, Khurana, Surender, Golding, Hana, van der Most, Robbert G., Dickler, Howard B., Germain, Ronald N., Schwartzberg, Pamela L., Tsang, John S.

Volltext

Impaired B cell immunity in acute myeloid leukemia patients after chemotherapy von Goswami, Meghali, Prince, Gabrielle, Biancotto, Angelique, Moir, Susan, Kardava, Lela, Santich, Brian H, Cheung, Foo, Kotliarov, Yuri, Chen, Jinguo, Shi, Rongye, Zhou, Huizhi, Golding, Hana, Manischewitz, Jody, King, Lisa, Kunz, Lauren M, Noonan, Kimberly, Borrello, Ivan M, Smith, B Douglas, Hourigan, Christopher S

Volltext

Electroporation of Synthetic DNA Antigens Offers Protection in Nonhuman Primates Challenged with Highly Pathogenic Avian Influenza Virus von LADDY, Dominick J, JIAN YAN, DRAGHIA-AKLI, Ruxandra, WEINER, David B, KHAN, Amir S, ANDERSEN, Hanne, COHN, Amanda, GREENHOUSE, Jack, LEWIS, Mark, MANISCHEWITZ, Jody, KING, Lisa R, GOLDING, Hana

Volltext

Bacterial HA1 Vaccine against Pandemic H5N1 Influenza Virus: Evidence of Oligomerization, Hemagglutination, and Cross-Protective Immunity in Ferrets von Khurana, Surender, Verma, Swati, Verma, Nitin, Crevar, Corey J, Carter, Donald M, Manischewitz, Jody, King, Lisa R, Ross, Ted M, Golding, Hana

Volltext

Properly folded bacterially expressed H1N1 hemagglutinin globular head and ectodomain vaccines protect ferrets against H1N1 pandemic influenza virus von Khurana, Surender, Verma, Swati, Verma, Nitin, Crevar, Corey J, Carter, Donald M, Manischewitz, Jody, King, Lisa R, Ross, Ted M, Golding, Hana

Volltext

Oral priming with replicating adenovirus serotype 4 followed by subunit H5N1 vaccine boost promotes antibody affinity maturation and expands H5N1 cross-clade neutralization von Khurana, Surender, Coyle, Elizabeth M, Manischewitz, Jody, King, Lisa R, Ishioka, Glenn, Alexander, Jeff, Smith, Jon, Gurwith, Marc, Golding, Hana

Volltext

AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization von Khurana, Surender, Coyle, Elizabeth M., Manischewitz, Jody, King, Lisa R., Gao, Jin, Germain, Ronald N., Schwartzberg, Pamela L., Tsang, John S., Golding, Hana

Volltext

Effects of Postchallenge Administration of ST-246 on Dissemination of IHD-J-Luc Vaccinia Virus in Normal Mice and in Immune-Deficient Mice Reconstituted with T Cells von Zaitseva, Marina, Shotwell, Elisabeth, Scott, John, Cruz, Stephanie, King, Lisa R, Manischewitz, Jody, Diaz, Claudia G, Jordan, Robert A, Grosenbach, Douglas W, Golding, Hana

Volltext

A rapid Flp-In system for expression of secreted H5N1 influenza hemagglutinin vaccine immunogen in mammalian cells von Lu, Hanxin, Khurana, Surender, Verma, Nitin, Manischewitz, Jody, King, Lisa, Beigel, John H, Golding, Hana

Volltext

Application of Bioluminescence Imaging to the Prediction of Lethality in Vaccinia Virus-Infected Mice von ZAITSEVA, Marina, KAPNICK, Senta M, SCOTT, John, KING, Lisa R, MANISCHEWITZ, Jody, SIROTA, Lev, KODIHALLI, Shantha, GOLDING, Hana

Volltext

Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection von Zaitseva, Marina, Blauvelt, Andrew, Lee, Shirley, Lapham, Cheryl K, Kiaus-Kovrun, Vera, Mostowski, Howard, Manischewitz, Jody, Golding, Hana

Volltext

Passive Immunotherapies Protect WRvFire and IHD-J-Luc Vaccinia Virus-Infected Mice from Lethality by Reducing Viral Loads in the Upper Respiratory Tract and Internal Organs von ZAITSEVA, Marina, KAPNICK, Senta M, LANTTO, Johan, WEIR, Jerry P, GOLDING, Hana, MESEDA, Clement A, SHOTWELL, Elisabeth, KING, Lisa R, MANISCHEWITZ, Jody, SCOTT, John, KODIHALLI, Shantha, MERCHLINSKY, Michael, NIELSEN, Henriette

Volltext

Dissection of Human Immunodeficiency Virus Type 1 Entry with Neutralizing Antibodies to gp41 Fusion Intermediates von Golding, Hana, Zaitseva, Marina, de Rosny, Eve, King, Lisa R, Manischewitz, Jody, Sidorov, Igor, Gorny, Miroslaw K, Zolla-Pazner, Susan, Dimitrov, Dimiter S, Weiss, Carol D

Volltext

Global analyses of human immune variation reveal baseline predictors of postvaccination responses von Tsang, John S, Schwartzberg, Pamela L, Kotliarov, Yuri, Biancotto, Angelique, Xie, Zhi, Germain, Ronald N, Wang, Ena, Olnes, Matthew J, Narayanan, Manikandan, Golding, Hana, Moir, Susan, Dickler, Howard B, Perl, Shira, Cheung, Foo

Volltext

Comparative Evaluation of the Immune Responses and Protection Engendered by LC16m8 and Dryvax Smallpox Vaccines in a Mouse Model von Meseda, Clement A, Mayer, Anne E, Kumar, Arunima, Garcia, Alonzo D, Campbell, Joseph, Listrani, Paul, Manischewitz, Jody, King, Lisa R, Golding, Hana, Merchlinsky, Michael, Weir, Jerry P

Volltext