The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis von Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.

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Assembly of Epithelial Tight Junctions Is Negatively Regulated by Par6 von Gao, Lin, Joberty, Gérard, Macara, Ian G.

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Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation von Lewis, Huw D, Liddle, John, Coote, Jim E, Atkinson, Stephen J, Barker, Michael D, Bax, Benjamin D, Bicker, Kevin L, Bingham, Ryan P, Campbell, Matthew, Chen, Yu Hua, Chung, Chun-wa, Craggs, Peter D, Davis, Rob P, Eberhard, Dirk, Joberty, Gerard, Lind, Kenneth E, Locke, Kelly, Maller, Claire, Martinod, Kimberly, Patten, Chris, Polyakova, Oxana, Rise, Cecil E, Rüdiger, Martin, Sheppard, Robert J, Slade, Daniel J, Thomas, Pamela, Thorpe, Jim, Yao, Gang, Drewes, Gerard, Wagner, Denisa D, Thompson, Paul R, Prinjha, Rab K, Wilson, David M

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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 von Joberty, Gérard, Petersen, Clark, Gao, Lin, Macara, Ian G

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New IDH1 mutant inhibitors for treatment of acute myeloid leukemia von Okoye-Okafor, Ujunwa C, Bartholdy, Boris, Cartier, Jessy, Gao, Enoch N, Pietrak, Beth, Rendina, Alan R, Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J, Reif, Alexander J, Schmidt, Stanley J, Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-Rao, Antony-Debre, Iléana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-Ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D, Schwartz, Benjamin, McCabe, Michael T, Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich

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Interrogating the Druggability of the 2‑Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics von Joberty, Gérard, Boesche, Markus, Brown, Jack A, Eberhard, Dirk, Garton, Neil S, Humphreys, Philip G, Mathieson, Toby, Muelbaier, Marcel, Ramsden, Nigel G, Reader, Valérie, Rueger, Anne, Sheppard, Robert J, Westaway, Susan M, Bantscheff, Marcus, Lee, Kevin, Wilson, David M, Prinjha, Rab K, Drewes, Gerard

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The Borgs, a New Family of Cdc42 and TC10 GTPase-Interacting Proteins von Joberty, Gérard, Perlungher, Richard R., Macara, Ian G.

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Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis von Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.

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Distinct cellular effects and interactions of the Rho-family GTPase TC10 von Neudauer, Cheryl L., Joberty, Gérard, Tatsis, Nia, Macara, Ian G.

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Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication von BORAWSKI, Jason, TROKE, Philip, BARYZA, Jeremy, TALLARICO, John, JOBERTY, Gerard, BANTSCHEFF, Marcus, SCHIRLE, Markus, BOUWMEESTER, Tewis, MATHY, Joanna E, KAI LIN, COMPTON, Teresa, LABOW, Mark, XIAOLING PUYANG, WIEDMANN, Brigitte, GAITHER, L. Alex, GIBAJA, Veronica, SHANCHAUN ZHAO, MICKANIN, Craig, LEIGHTON-DAVIES, Juliet, WILSON, Christopher J, MYER, Vic, CORNELLATARACIDO, Ivan

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Comprehensive Proteomic Analysis of Human Par Protein Complexes Reveals an Interconnected Protein Network von Brajenovic, Miro, Joberty, Gerard, Küster, Bernhard, Bouwmeester, Tewis, Drewes, Gerard

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Borg proteins control septin organization and are negatively regulated by Cdc42 von Joberty, Gérard, Macara, Ian G, Perlungher, Richard R, Sheffield, Peter J, Kinoshita, Makoto, Noda, Makoto, Haystead, Timothy

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Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV) von Bonavia, Aurelio, Franti, Michael, Pusateri Keaney, Erin, Kuhen, Kelli, Seepersaud, Mohindra, Radetich, Branko, Shao, Jian, Honda, Ayako, Dewhurst, Janetta, Balabanis, Kara, Monroe, James, Wolff, Karen, Osborne, Colin, Lanieri, Leanne, Hoffmaster, Keith, Amin, Jakal, Markovits, Judit, Broome, Michelle, Skuba, Elizabeth, Cornella-Taracido, Ivan, Joberty, Gerard, Bouwmeester, Tewis, Hamann, Lawrence, Tallarico, John A, Tommasi, Ruben, Compton, Teresa, Bushell, Simon M

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Multiple cyclophilins involved in different cellular pathways mediate HCV replication von Gaither, L. Alex, Borawski, Jason, Anderson, Leah J, Balabanis, Kara A, Devay, Piroska, Joberty, Gerard, Rau, Christina, Schirle, Markus, Bouwmeester, Tewis, Mickanin, Craig, Zhao, ShanChuan, Vickers, Chad, Lee, Lac, Deng, Gejing, Baryza, Jeremy, Fujimoto, Roger A, Lin, Kai, Compton, Teresa, Wiedmann, Brigitte

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Biochemical characterization of USP7 reveals post‐translational modification sites and structural requirements for substrate processing and subcellular localization von Fernández‐Montalván, Amaury, Bouwmeester, Tewis, Joberty, Gerard, Mader, Robert, Mahnke, Marion, Pierrat, Benoit, Schlaeppi, Jean‐Marc, Worpenberg, Susanne, Gerhartz, Bernd

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Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress von Qin, Pu, Arabacilar, Pelin, Bernard, Roberta E, Bao, Weike, Olzinski, Alan R, Guo, Yuanjun, Lal, Hind, Eisennagel, Stephen H, Platchek, Michael C, Xie, Wensheng, Del Rosario, Julius, Nayal, Mohamad, Lu, Quinn, Roethke, Theresa, Schnackenberg, Christine G, Wright, Fe, Quaile, Michael P, Halsey, Wendy S, Hughes, Ashley M, Sathe, Ganesh M, Livi, George P, Kirkpatrick, Robert B, Qu, Xiaoyan A, Rajpal, Deepak K, Faelth Savitski, Maria, Bantscheff, Marcus, Joberty, Gerard, Bergamini, Giovanna, Force, Thomas L, Gatto, Jr, Gregory J, Hu, Erding, Willette, Robert N

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Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics von Haupt, Armin, Joberty, Gerard, Bantscheff, Marcus, Fröhlich, Holger, Stehr, Henning, Schweiger, Michal R, Fischer, Axel, Kerick, Martin, Boerno, Stefan T, Dahl, Andreas, Lappe, Michael, Lehrach, Hans, Gonzalez, Cayetano, Drewes, Gerard, Lange, Bodo Mh

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High affinity Rab3 binding is dispensable for Rabphilin-dependent potentiation of stimulated secretion von Joberty, G, Stabila, P F, Coppola, T, Macara, I G, Regazzi, R

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Biological plasticity rescues target activity in CRISPR knock outs von Smits, Arne H., Ziebell, Frederik, Joberty, Gerard, Zinn, Nico, Mueller, William F., Clauder-Münster, Sandra, Eberhard, Dirk, Fälth Savitski, Maria, Grandi, Paola, Jakob, Petra, Michon, Anne-Marie, Sun, Hanice, Tessmer, Karen, Bürckstümmer, Tilmann, Bantscheff, Marcus, Steinmetz, Lars M., Drewes, Gerard, Huber, Wolfgang

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response von Kruidenier, Laurens, Chung, Chun-wa, Cheng, Zhongjun, Liddle, John, Che, KaHing, Joberty, Gerard, Bantscheff, Marcus, Bountra, Chas, Bridges, Angela, Diallo, Hawa, Eberhard, Dirk, Hutchinson, Sue, Jones, Emma, Katso, Roy, Leveridge, Melanie, Mander, Palwinder K., Mosley, Julie, Ramirez-Molina, Cesar, Rowland, Paul, Schofield, Christopher J., Sheppard, Robert J., Smith, Julia E., Swales, Catherine, Tanner, Robert, Thomas, Pamela, Tumber, Anthony, Drewes, Gerard, Oppermann, Udo, Patel, Dinshaw J., Lee, Kevin, Wilson, David M.

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