A Study on the Impact Resistance of Plastic Underbody Parts von Youn, Jee Young, Kim, Seok Hwan, Jin, Yong Sun (Steven)

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A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells von Bu, Pengcheng, Chen, Kai-Yuan, Chen, Joyce Huan, Wang, Lihua, Walters, Jewell, Shin, Yong Jun, Goerger, Julian P., Sun, Jian, Witherspoon, Mavee, Rakhilin, Nikolai, Li, Jiahe, Yang, Herman, Milsom, Jeff, Lee, Sang, Zipfel, Warren, Jin, Moonsoo M., Gümüş, Zeynep H., Lipkin, Steven M., Shen, Xiling

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Dose-dependent detoxication of the airborne pollutant benzene in a randomized trial of broccoli sprout beverage in Qidong, China von Chen, Jian-Guo, Johnson, Jamie, Egner, Patricia, Ng, Derek, Zhu, Jian, Wang, Jin-Bing, Xue, Xue-Feng, Sun, Yan, Zhang, Yong-Hui, Lu, Ling-Ling, Chen, Yong-Sheng, Wu, Yan, Zhu, Yuan-Rong, Carmella, Steven, Hecht, Stephen, Jacobson, Lisa, Muñoz, Alvaro, Kensler, Kevin, Rule, Ana, Fahey, Jed, Kensler, Thomas, Groopman, John

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Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease von Zhou, Qing, Yu, Xiaomin, Demirkaya, Erkan, Deuitch, Natalie, Stone, Deborah, Tsai, Wanxia Li, Kuehn, Hye Sun, Wang, Hongying, Yang, Dan, Park, Yong Hwan, Ombrello, Amanda K., Blake, Mary, Romeo, Tina, Remmers, Elaine F., Chae, Jae Jin, Mullikin, James C., Güzel, Ferhat, Milner, Joshua D., Boehm, Manfred, Rosenzweig, Sergio D., Gadina, Massimo, Welch, Steven B., Özen, Seza, Topaloglu, Rezan, Abinun, Mario, Kastner, Daniel L., Aksentijevich, Ivona

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Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk von Zhang, Ben, Jia, Wei-Hua, Matsuda, Koichi, Kweon, Sun-Seog, Matsuo, Keitaro, Xiang, Yong-Bing, Shin, Aesun, Jee, Sun Ha, Kim, Dong-Hyun, Cai, Qiuyin, Long, Jirong, Shi, Jiajun, Wen, Wanqing, Yang, Gong, Zhang, Yanfeng, Li, Chun, Li, Bingshan, Guo, Yan, Ren, Zefang, Ji, Bu-Tian, Pan, Zhi-Zhong, Takahashi, Atsushi, Shin, Min-Ho, Matsuda, Fumihiko, Gao, Yu-Tang, Oh, Jae Hwan, Kim, Soriul, Ahn, Yoon-Ok, Chan, Andrew T, Chang-Claude, Jenny, Slattery, Martha L, Gruber, Stephen B, Schumacher, Fredrick R, Stenzel, Stephanie L, Casey, Graham, Kim, Hyeong-Rok, Jeong, Jin-Young, Park, Ji Won, Li, Hong-Lan, Hosono, Satoyo, Cho, Sang-Hee, Kubo, Michiaki, Shu, Xiao-Ou, Zeng, Yi-Xin, Zheng, Wei

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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy von Fang, Yong, McGrail, Daniel J, Sun, Chaoyang, Labrie, Marilyne, Chen, Xiaohua, Zhang, Dong, Ju, Zhenlin, Vellano, Christopher P, Lu, Yiling, Li, Yongsheng, Jeong, Kang Jin, Ding, Zhiyong, Liang, Jiyong, Wang, Steven W, Dai, Hui, Lee, Sanghoon, Sahni, Nidhi, Mercado-Uribe, Imelda, Kim, Tae-Beom, Chen, Ken, Lin, Shiaw-Yih, Peng, Guang, Westin, Shannon N, Liu, Jinsong, O'Connor, Mark J, Yap, Timothy A, Mills, Gordon B

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Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer von Jia, Wei-Hua, Zhang, Ben, Matsuo, Keitaro, Shin, Aesun, Xiang, Yong-Bing, Jee, Sun Ha, Kim, Dong-Hyun, Ren, Zefang, Cai, Qiuyin, Long, Jirong, Shi, Jiajun, Wen, Wanqing, Yang, Gong, Delahanty, Ryan J, Ji, Bu-Tian, Pan, Zhi-Zhong, Matsuda, Fumihiko, Gao, Yu-Tang, Oh, Jae Hwan, Ahn, Yoon-Ok, Park, Eun Jung, Li, Hong-Lan, Park, Ji Won, Jo, Jaeseong, Jeong, Jin-Young, Hosono, Satoyo, Casey, Graham, Peters, Ulrike, Shu, Xiao-Ou, Zeng, Yi-Xin, Zheng, Wei

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Effective radiative forcing of anthropogenic aerosols in E3SM version 1: historical changes, causality, decomposition, and parameterization sensitivities von Zhang, Kai, Zhang, Wentao, Wan, Hui, Rasch, Philip J, Ghan, Steven J, Easter, Richard C, Shi, Xiangjun, Wang, Yong, Wang, Hailong, Ma, Po-Lun, Zhang, Shixuan, Sun, Jian, Burrows, Susannah M, Shrivastava, Manish, Singh, Balwinder, Qian, Yun, Liu, Xiaohong, Golaz, Jean-Christophe, Tang, Qi, Zheng, Xue, Xie, Shaocheng, Lin, Wuyin, Feng, Yan, Wang, Minghuai, Yoon, Jin-Ho, Leung, L. Ruby

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Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer von Drilon, Alexander, Camidge, D. Ross, Lin, Jessica J., Kim, Sang-We, Solomon, Benjamin J., Dziadziuszko, Rafal, Besse, Benjamin, Goto, Koichi, de Langen, Adrianus Johannes, Wolf, Jürgen, Lee, Ki Hyeong, Popat, Sanjay, Springfeld, Christoph, Nagasaka, Misako, Felip, Enriqueta, Yang, Nong, Velcheti, Vamsidhar, Lu, Shun, Kao, Steven, Dooms, Christophe, Krebs, Matthew G., Yao, Wenxiu, Beg, Muhammad Shaalan, Hu, Xiufeng, Moro-Sibilot, Denis, Cheema, Parneet, Stopatschinskaja, Shanna, Mehta, Minal, Trone, Denise, Graber, Armin, Sims, Gregory, Yuan, Yong, Cho, Byoung Chul

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Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants von Dadaev, Tokhir, Saunders, Edward J., Anokian, Ezequiel, Leongamornlert, Daniel A., Brook, Mark N., Cieza-Borrella, Clara, Mijuskovic, Martina, Schumacher, Fredrick R., Benlloch, Sara, Ahmed, Mahbubl, Goh, Chee, Sheng, Xin, Lophatananon, Artitaya, Gapstur, Susan M., Goodman, Phyllis, Moya, Leire, Clements, Judith, Horvath, Lisa, Risbridger, Gail, Nordström, Tobias, Pashayan, Nora, Schleutker, Johanna, Tammela, Teuvo L. J., Weinstein, Stephanie, Wolk, Alicja, West, Catharine, Dunning, Alison M., Burnet, Neil, Mucci, Lorelei, Giovannucci, Edward, Andriole, Gerald, Koutros, Stella, Orntoft, Torben Falck, Borre, Michael, Maehle, Lovise, Grindedal, Eli Marie, Donovan, Jenny L., Travis, Ruth C., Key, Tim J., Hamilton, Robert J., Stern, Mariana C., Kerns, Sarah, Lu, Yong-Jie, Zhang, Hong-Wei, Wang, Guomin, Sun, Zan, Giles, Graham G., Southey, Melissa C., MacInnis, Robert J., Drake, Bettina F., Vega, Ana, Fachal, Laura, Szulkin, Robert, Eklund, Martin, Penney, Kathryn L., Park, Jong Y., Sellers, Thomas A., Lin, Hui-Yi, Cybulski, Cezary, Nordestgaard, Børge G., Weisher, Maren, Iversen, Peter, Kim, Jeri, Teixeira, Manuel R., Cardoso, Marta, Steele, Linda, Ost, Piet, Razack, Azad, Lim, Jasmine, Teo, Soo-Hwang, Lin, Daniel W., Newcomb, Lisa F., Lessel, Davor, Gamulin, Marija, Usmani, Nawaid, Slavov, Chavdar, Parliament, Matthew, Van den Broeck, Thomas, Larkin, Samantha, Townsend, Paul A., Aukim-Hastie, Claire, Roobol, Monique J., Jenster, Guido, van Schaik, Ron H. N., Menegaux, Florence, Koudou, Yves Akoli, Xu, Jianfeng, Cannon-Albright, Lisa, Pandha, Hardev, Kierzek, Andrzej, Turman, Constance, Ma, Jing, Hunter, David J., Kolonel, Laurence N., Le Marchand, Loic, Hoover, Robert N., Kraft, Peter, Wiklund, Fredrik, Conti, David V., Kote-Jarai, Zsofia

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Abstract 15649: Terf2ip K240 Sumoylation Drives Endothelial Senescence and Atherogenesis via Activating Parp1 von Chau, Khanh, Imanishi, Masaki, Li, Shengyu, Kotla, Sivareddy, Ko, Kyung A, Nguyen, Minh T, Berrios Turcios, Estefani, Abe, Rei, Zhang, Aijun, McBeath, Elena, Fujiwara, Keigi, Jin Gi, Young, Heo, Kyung-Sun, Cheng, Jinke, Thomas, Tamlyn, Schadler, Keri, Gupte, Anisha A, Shen, Ying H, Lin, Steven, Yeh, Edward T, Fujiwra, Keigi, Hamilton, Dale, Cooke, John P, Wang, Guangyu, Abe, Junichi, Le, Nhat Tu, Zuo, Yong, Sharma, Amrish

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Effective radiative forcing of anthropogenic aerosols in E3SMv1: historical changes, causality, decomposition, and parameterization sensitivities von Zhang, Kai, Zhang, Wentao, Wan, Hui, Rasch, Philip J., Ghan, Steven J., Easter, Richard C., Shi, Xiangjun, Wang, Yong, Wang, Hailong, Ma, Po-Lun, Zhang, Shixuan, Sun, Jian, Burrows, Susannah, Shrivastava, Manish, Singh, Balwinder, Qian, Yun, Liu, Xiaohong, Golaz, Jean-Christophe, Tang, Qi, Zheng, Xue, Xie, Shaocheng, Lin, Wuyin, Feng, Yan, Wang, Minghuai, Yoon, Jin-Ho, Leung, Ruby L.

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Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk von Staser, Karl, Park, Su-Jung, Rhodes, Steven D, Zeng, Yi, He, Yong Zheng, Shew, Matthew A, Gehlhausen, Jeffrey R, Cerabona, Donna, Menon, Keshav, Chen, Shi, Sun, Zejin, Yuan, Jin, Ingram, David A, Nalepa, Grzegorz, Yang, Feng-Chun, Clapp, D Wade

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Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain von Wu, Yong-Jin, Conway, Charles M., Sun, Li-Qiang, Machet, Frederic, Chen, Jie, Chen, Ping, He, Huan, Bourin, Clotilde, Calandra, Vincenzo, Polino, Joseph L., Davis, Carl D., Heman, Karen, Gribkoff, Valentin K., Boissard, Christopher G., Knox, Ronald J., Thompson, Mark W., Fitzpatrick, William, Weaver, David, Harden, David G., Natale, Joanne, Dworetzky, Steven I., Starrett, John E.

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Fluorine Substitution Can Block CYP3A4 Metabolism-Dependent Inhibition:  Identification of (S)-N-[1-(4-Fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an Ora... von Wu, Yong-Jin, Davis, Carl D, Dworetzky, Steven, Fitzpatrick, William C, Harden, David, He, Huan, Knox, Ronald J, Newton, Amy E, Philip, Thomas, Polson, Craig, Sivarao, Digavalli V, Sun, Li-Qiang, Tertyshnikova, Svetlana, Weaver, David, Yeola, Suresh, Zoeckler, Mary, Sinz, Michael W

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(S)-N-[1-(3-Morpholin-4-ylphenyl)ethyl]- 3-phenylacrylamide:  An Orally Bioavailable KCNQ2 Opener with Significant Activity in a Cortical Spreading Depression Model of Migraine von Wu, Yong-Jin, Boissard, Christopher G, Greco, Corinne, Gribkoff, Valentin K, Harden, David G, He, Huan, L'Heureux, Alexandre, Kang, Shing Hong, Kinney, Gene G, Knox, Ronald J, Natale, Joanne, Newton, Amy E, Lehtinen-Oboma, Sanna, Sinz, Michael W, Sivarao, Digavalli V, Starrett, John E, Sun, Li-Qiang, Tertyshnikova, Svetlana, Thompson, Mark W, Weaver, David, Wong, Henry S, Zhang, Lei, Dworetzky, Steven I

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Synthesis and Structure−Activity Relationship of Acrylamides as KCNQ2 Potassium Channel Openers von Wu, Yong-Jin, He, Huan, Sun, Li-Qiang, L'Heureux, Alexandre, Chen, Jie, Dextraze, Pierre, Starrett, John E, Boissard, Christopher G, Gribkoff, Valentin K, Natale, Joanne, Dworetzky, Steven I

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Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-ac r ylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain von Wu, Yong-Jin, Conway, Charles M, Sun, Li-Qiang, Machet, Frederic, Chen, Jie, Chen, Ping, He, Huan, Bourin, Clotilde, Calandra, Vincenzo, Polino, Joseph L, Davis, Carl D, Heman, Karen, Gribkoff, Valentin K, Boissard, Christopher G, Knox, Ronald J, Thompson, Mark W, Fitzpatrick, William, Weaver, David, Harden, David G, Natale, Joanne, Dworetzky, Steven I, Starrett, John E

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( S)- N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2 H-benzo [1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hypere... von Wu, Yong-Jin, Boissard, Christopher G, Chen, Jie, Fitzpatrick, William, Gao, Qi, Gribkoff, Valentin K, Harden, David G, He, Huan, Knox, Ronald J, Natale, Joanne, Pieschl, Rick L, Starrett, John E, Sun, Li-Qiang, Thompson, Mark, Weaver, David, Wu, Dedong, Dworetzky, Steven I

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Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1 H-indol-5-yl)-ethyl acrylamides von Wu, Yong-Jin, Sun, Li-Qiang, He, Huan, Chen, Jie, Starrett, John E, Dextraze, Pierre, Daris, Jean-Paul, Boissard, Christopher G, Pieschl, Rick L, Gribkoff, Valentin K, Natale, Joanne, Knox, Ronald J, Harden, David G, Thompson, Mark W, Fitzpatrick, William, Weaver, David, Wu, Dedong, Gao, Qi, Dworetzky, Steven I

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