Inhibition of extracellular nucleotides hydrolysis intensifies the allergic bronchospasm. A novel protective role of ectonucleotidases von Chávez, J., Vargas, M. H., Rebollar‐Ayala, D. C., Díaz‐Hernández, V., Cruz‐Valderrama, J. E., Flores‐Soto, E., Flores‐García, M., Jiménez‐Vargas, N. N., Barajas‐López, C., Montaño, L. M.

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Changes in signalling from faecal neuroactive metabolites following dietary modulation of IBS pain von Tuck, Caroline J, Abu Omar, Amal, De Palma, Giada, Osman, Samira, Jiménez-Vargas, Nestor N, Yu, Yang, Bennet, Sean MP, Lopez-Lopez, Cintya, Jaramillo-Polanco, Josue O, Baker, Corey C, Bennett, Aidan SW, Guzman-Rodriguez, Mabel, Tsang, Quentin, Alward, Taylor, Rolland, Sebastien, Morissette, Celine, Verdu, Elena F, Bercik, Premysl, Vanner, Stephen J, Lomax, Alan E, Reed, David E

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Dietary monosodium glutamate increases visceral hypersensitivity in a mouse model of visceral pain von Brant, Bailey J. A., Yu, Yang, Omar, Amal Abu, Jaramillo Polanco, Josue O., Lopez Lopez, Cintya D., Jiménez Vargas, Nestor N., Tsang, Quentin, McDonell, Abby, Takami, Kaede, Reed, David E., Lomax, Alan E., Vanner, Stephen J., Tuck, Caroline J.

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The impact of dietary fermentable carbohydrates on a postinflammatory model of irritable bowel syndrome von Tuck, Caroline J., Caminero, Alberto, Jiménez Vargas, Nestor N., Soltys, Carmen L, Jaramillo Polanco, Josue O., Lopez Lopez, Cintya D., Constante, Marco, Lourenssen, Sandra R., Verdu, Elena F., Muir, Jane G., Lomax, Alan E., Reed, David E., Vanner, Stephen J.

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Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome von Jimenez-Vargas, Nestor N., Pattison, Luke A., Zhao, Peishen, Lieu, TinaMarie, Latorre, Rocco, Jensen, Dane D., Castro, Joel, Aurelio, Luigi, Le, Giang T., Flynn, Bernard, Herenbrink, Carmen Klein, Yeatman, Holly R., Edgington-Mitchell, Laura, Porter, Christopher J. H., Halls, Michelle L., Canals, Meritxell, Veldhuis, Nicholas A., Poole, Daniel P., McLean, Peter, Hicks, Gareth A., Scheff, Nicole, Chen, Elyssa, Bhattacharya, Aditi, Schmidt, Brian L., Brierley, Stuart M., Vanner, Stephen J., Bunnett, Nigel W.

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431 Protease-Activated Receptor 2 Signals from Endosomes to Control Sensitivity of Nociceptors von Zhao, Peishen, Jiménez-Vargas, Nestor N, Pattison, Luke, Vanner, Stephen, Bunnett, Nigel

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Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain von Zhao, Peishen, Lieu, TinaMarie, Barlow, Nicholas, Sostegni, Silvia, Haerteis, Silke, Korbmacher, Christoph, Liedtke, Wolfgang, Jimenez-Vargas, Nestor N., Vanner, Stephen J., Bunnett, Nigel W.

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Proteases in Colonic Tissue from IBS Patients Evoke Sustained Excitability of Nociceptive DRG Neurons via Endosomal Signaling von Jiménez-Vargas, Nestor N, Reed, David E, Bunnett, Nigel W, Vanner, Stephen

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Challenges in gastrointestinal research in Latin America von Guzman, Mabel, Canedo-Marroquín, Gisela, Jimenez-Vargas, Nestor N.

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Sa1840 Endogenous Opioids Evoke a Sustained Antinociceptive Effect via Endosomal Signaling in Nociceptive DRG Neurons von Jiménez-Vargas, Nestor N, Poole, Daniel P, Lopez, Cintya D. Lopez, Polanco, Josue O. Jaramillo, Lomax, Alan E, Bunnett, Nigel, Vanner, Stephen

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Diet-Microbiota Interactions Underlie Symptoms' Generation in IBS von De Palma, Giada, Reed, David E, Pigrau, Marc, Lu, Jun, Sidani, Sacha, Zhang, Yong, Yu, Yang, Jiménez-Vargas, Nestor N, Sessenwein, Jessica, Lopez Lopez, Cintya D, Jaramillo Polanco, Josue O, Verdu, Elena F, Collins, Stephen M, Lomax, Alan E, Beyak, Michael, Vanner, Stephen, Bercik, Premysl

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Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain von Jimenez-Vargas, Nestor N., Gong, Jing, Wisdom, Matthew J., Jensen, Dane D., Latorre, Rocco, Hegron, Alan, Teng, Shavonne, DiCello, Jesse J., Rajasekhar, Pradeep, Veldhuis, Nicholas A., Carbone, Simona E., Yu, Yang, Lopez-Lopez, Cintya, Jaramillo-Polanco, Josue, Canals, Meritxell, Reed, David E., Lomax, Alan E., Schmidt, Brian L., Leong, Kam W., Vanner, Stephen J., Halls, Michelle L., Bunnett, Nigel W., Poole, Daniel P.

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Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity von Baker, Corey C., Sessenwein, Jessica L., Wood, Hannah M., Yu, Yang, Tsang, Quentin, Alward, Taylor A., Jimenez Vargas, Nestor N., Omar, Amal Abu, McDonnel, Abby, Segal, Julia P., Sjaarda, Calvin P., Bunnett, Nigel W., Schmidt, Brian L., Caminero, Alberto, Boev, Nadejda, Bannerman, Courtney A., Ghasemlou, Nader, Sheth, Prameet M., Vanner, Stephen J., Reed, David E., Lomax, Alan E.

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Legumain Induces Oral Cancer Pain by Biased Agonism of Protease-Activated Receptor-2 von Tu, Nguyen Huu, Jensen, Dane D., Anderson, Bethany M., Chen, Elyssa, Jimenez-Vargas, Nestor N., Scheff, Nicole N., Inoue, Kenji, Tran, Hung D., Dolan, John C., Meek, Tamaryn A., Hollenberg, Morley D., Liu, Cheng Z., Vanner, Stephen J., Janal, Malvin N., Bunnett, Nigel W., Edgington-Mitchell, Laura E., Schmidt, Brian L.

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Stress activates pronociceptive endogenous opioid signalling in DRG neurons during chronic colitis von Guerrero-Alba, Raquel, Valdez-Morales, Eduardo E, Jimenez-Vargas, Nestor N, Lopez-Lopez, Cintya, Jaramillo-Polanco, Josue, Okamoto, Takanobu, Nasser, Yasmin, Bunnett, Nigel W, Lomax, Alan E, Vanner, Stephen J

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Protein kinase D and Gβγ mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2 von Zhao, Peishen, Pattison, Luke A., Jensen, Dane D., Jimenez-Vargas, Nestor N., Latorre, Rocco, Lieu, TinaMarie, Jaramillo, Josue O., Lopez-Lopez, Cintya, Poole, Daniel P., Vanner, Stephen J., Schmidt, Brian L., Bunnett, Nigel W.

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Protein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane von Jensen, Dane D., Zhao, Peishen, Jimenez-Vargas, Nestor N., Lieu, TinaMarie, Gerges, Marina, Yeatman, Holly R., Canals, Meritxell, Vanner, Stephen J., Poole, Daniel P., Bunnett, Nigel W.

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A243 HISTAMINE H1-RECEPTOR ANTAGONISTS SUPPRESS THE HYPEREXCITABILITY OF NOCICEPTIVE NEURONS EXPOSED TO IBS-C PATIENT STOOL SUPERNATANTS von Neary, E, Jiménez-Vargas, N N, Lomax, A E, Reed, D E, Vanner, S

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Mo1604 - Colonic Proteases Evoke Sustained Pain Signaling via a Novel Endosomal Pathway in Neurons von Jiménez-Vargas, Nestor N., Bunnett, Nigel W., Vanner, Stephen

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Sa1232 NOVEL PH-SENSITIVE OPIOID DOES NOT INDUCE TOLERANCE IN A COLITIS MOUSE MODEL von Jiménez-Vargas, Nestor N., Degro, Claudius E., Tsang, Quentin K., Guzman-Rodriguez, Mabel, Lomax, Alan E., Reed, David E., Stein, Christoph, Bunnett, Nigel W., Vanner, Stephen

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