Randomised clinical study: discrepancies between patient‐reported outcomes and endoscopic appearance in moderate to severe ulcerative colitis von Jharap, B., Sandborn, W. J., Reinisch, W., D'Haens, G., Robinson, A. M., Wang, W., Huang, B., Lazar, A., Thakkar, R. B., Colombel, J.‐F.

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Effects of concomitant immunomodulators on the pharmacokinetics, efficacy and safety of adalimumab in patients with Crohn's disease or ulcerative colitis who had failed conventiona... von Colombel, J.‐F., Jharap, B., Sandborn, W. J., Feagan, B., Peyrin‐Biroulet, L., Eichner, S. F., Robinson, A. M., Mostafa, N. M., Zhou, Q., Thakkar, R. B.

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Thiopurine therapy in inflammatory bowel disease patients: Analyses of two 8‐year intercept cohorts von Jharap, B., Seinen, M.L., de Boer, N.K.H., van Ginkel, J.R., Linskens, R.K., Kneppelhout, J.C., Mulder, C.J.J., van Bodegraven, A.A.

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Long‐term follow‐up of children exposed intrauterine to maternal thiopurine therapy during pregnancy in females with inflammatory bowel disease von Meij, T. G. J., Jharap, B., Kneepkens, C. M. F., Bodegraven, A. A., Boer, N. K. H.

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Influence of 5‐aminosalicylic acid on 6‐thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy von de Graaf, P, de Boer, NKH, Wong, DR, Karner, S, Jharap, B, Hooymans, PM, Veldkamp, AI, Mulder, CJJ, van Bodegraven, AA, Schwab, M

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Limited stability of thiopurine metabolites in blood samples: Relevant in research and clinical practise von de Graaf, P., Vos, R.M., de Boer, N.H.K., Sinjewel, A., Jharap, B., Mulder, C.J.J., van Bodegraven, A.A., Veldkamp, A.I.

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Biotransformation of 6‐thioguanine in inflammatory bowel disease patients: a comparison of oral and intravenous administration of 6‐thioguanine von Jharap, B, de Boer, NKH, Vos, RM, Smid, K, Zwiers, A, Peters, GJ, Mulder, CJJ, Wilhelm, AJ, van Bodegraven, AA

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Letter: thiopurines during pregnancy and intrauterine exposure to metabolites von de Boer, N. K. H., Jharap, B., Seinen, M. L., van Bodegraven, A. A.

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Intrauterine exposure to thiopurines von Jharap, B., Seinen, M.L., van Bodegraven, A.A., de Boer, N.K.

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Immunomodulator withdrawal from anti-TNF therapy is not associated with loss of response in inflammatory bowel disease von Mahmoud, Remi, Schultheiss, Hans-Paul, Louwers, Jonas, van der Kaaij, M T, van Hellemondt, B P, Mahmmod, N, van Boeckel, P G, Jharap, B, Fidder, Herma, Oldenburg, Bas

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P414 Obesity is associated with a higher risk of immunogenicity to adalimumab, but not to infliximab in patients with Inflammatory Bowel Disease von Mahmoud, R, Schultheiss, J, Louwers, J, van der Kaaij, M, van Hellemondt, B, Mahmmod, N, van Boeckel, P, Jharap, B, Fidder, H, Oldenburg, B

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P299 Loss-of-response to anti-tumour necrosis factor-α critically depends on treatment duration in patients with Inflammatory Bowel Disease von Schultheiss, J, Mahmoud, R, Louwers, J, van der Kaaij, M, van Hellemondt, B, van Boeckel, P, Mahmmod, N, Jharap, B, Fidder, H, Oldenburg, B

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DOP75 Loss-of-response and immunogenicity following immunomodulator withdrawal from anti-tumour necrosis factor alpha combination therapy: Results from a large retrospective cohort... von Mahmoud, R, Schultheiss, J, Louwers, J, van der Kaaij, M, van Hellemondt, B, Mahmmod, N, van Boeckel, P, Jharap, B, Fidder, H, Oldenburg, B

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DOP70 Anti-TNF withdrawal according to a risk-stratified protocol does not reduce the risk of relapse in patients with Inflammatory Bowel Disease in endoscopic remission: A prospec... von Mahmoud, R, Savelkoul, E, Mares, W, Goetgebuer, R, Witteman, B, de Koning, D, Minderhoud, I, van Tuyl, S, van Boeckel, P, Mahmmod, N, Lutgens, M, Horjus, C, Römkens, T, Akol-Simsek, D, Jansen, J, Hoentjen, F, Jharap, B, Oldenburg, B

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P309 Withdrawal of thiopurines in Inflammatory Bowel Disease patients in stable remission: a prospective, multicentre cohort study von Savelkoul, E, Mahmoud, R, De Jong, D, Van Dop, W, Römkens, T, Nissen, L, Mahmmod, N, Van Boeckel, P, Lutgens, M, Mares, W, Epping, L, Minderhoud, I, Jansen, J, Gisbertz, I, Boekema, P, De Koning, D, Horjus, C, Jharap, B, Oldenburg, B, Hoentjen, F

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P687 Prevalence of iron deficiency and anaemia in the outpatient Inflammatory Bowel Disease population: a Dutch national cross-sectional study von Loveikyte, R, Boer, M, van der Meulen, C N, ter Steege, R W F, Tack, G, Kuyvenhoven, J, Jharap, B, Vu, M K, Vogelaar, L, West, R L, van der Marel, S, Römkens, T, Mujagic, Z, Hoentjen, F, van Bodegraven, A A, van Schaik, F D M, de Vries, A C, Dijkstra, G, van der Meulen-de Jong, A E

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DOP75 Effectiveness and Safety of tofacitinib versus vedolizumab in Patients with Ulcerative Colitis; A Nationwide, ICC Registry study von Straatmijer, T, Visschedijk, M, de Vries, A, Hoentjen, F, van Bodegraven, A A, Bodelier, A G L, de Boer, N K H, Dijkstra, G, Festen, E A M, Horjus, C, Jansen, J M, Jharap, B, Mares, W, Oldenburg, B, Ponsioen, C Y, Romkens, T E H, Srivastava, N, van der Voorn, M M, West, R L, van der Woude, J C, Wolvers, M D J, Pierik, M, van der Meulen, A E, Duijvestein, M

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P284 Prophylactic medication for the prevention of endoscopic recurrence after ileocolonic resection in Crohn’s disease: a prospective study based on clinical risk stratification von Arkenbosch, J H, Beelen, E M J, Dijkstra, G, Romberg-Camps, M, Duijvestein, M, Hoentjen, F, van der Marel, S, Maljaars, P W J, Jansen, S, de Boer, N K, West, R, Horjus, C, Stassen, L P S, van Schaik, F, van Ruler, O, Jharap, B J H, Erler, N E, Doukas, M, Ooms, A H A G, Kats-Ugurlu, G, van der Woude, J, De Vries, A C

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P228 Prehabilitation strategies prior to ileocolonic resection in Crohn’s disease in a prospective cohort study: a missed window of opportunity? von Ruiterkamp, M, Arkenbosch, J, van Ruler, O, van der Marel, S, van Dongen, K, Maljaars, P W J, Hoentjen, F, West, R, Jharap, B, Dijkstra, G, Campmans-Kuijpers, M, Jansen, S, Romberg-Camps, M, Stassen, L, van der Woude, C J, de Vries, A

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Vulvar and vaginal neoplasia in women with inflammatory bowel disease von Rouvroye, Maxine D., Tack, Greetje J., Mom, Constantijne H., Lissenberg-Witte, Birgit I., Pierik, Marieke J., Neefjes-Borst, E. Andra, de Boer, Nanne K.H., Löwenberg, M., Bodelier, A., Verbeek, W.H., Schoon, E., Witteman, E.M., Herwaarden, M.A., Van Der Woude, C.J., Lutgens, M., Kouw, E., Van Der Veek, P.J., van der Hulst, R.W., Sipkema, H., Nissen, L.H.C., Bus, P.J., van der Meulen, A.E., De Bruijne, F.H., van der Waaij, L.A., Noomen, C.G., Jharap, B., Schmittgens, S., Jansen, J.M., Hoentjen, F., Lammertink, M.H.A., Houben, G.M.P., Minderhoud, I.M., Dijkstra, G., Oldenburg, B., Sikkens, M.S.G., Van Tuyl, S.A., van Bodegraven, A.A.

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