Gemtuzumab ozogamicin plus midostaurin in conjunction with standard intensive therapy for FLT3 - mutated acute myeloid leukemia patients - Czech center experience von Weinbergerová, Barbora, Čerňan, Martin, Kabut, Tomáš, Semerád, Lukáš, Podstavková, Natália, Szotkowski, Tomáš, Ježíšková, Ivana, Mayer, Jiří

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Why are not all eligible chronic myeloid leukemia patients willing to attempt tyrosine kinase inhibitor discontinuation? A Czech nationwide analysis related to the TKI stopping tri... von Žáčková, Daniela, Semerád, Lukáš, Faber, Edgar, Klamová, Hana, Stejskal, Lukáš, Bělohlávková, Petra, Karas, Michal, Cmunt, Eduard, Černá, Olga, Procházková, Jiřina, Čičátková, Petra, Kvetková, Anežka, Horňák, Tomáš, Skoumalová, Ivana, Srbová, Dana, Šálek, Cyril, Buffa, David, Voglová, Jaroslava, Jurček, Tomáš, Folta, Adam, Ježíšková, Ivana, Žižková, Hana, Machová Poláková, Kateřina, Papajík, Tomáš, Žák, Pavel, Jindra, Pavel, Svobodník, Adam, Štěpánová, Radka, Mayer, Jiří

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MethScore as a new comprehensive DNA methylation-based value refining the prognosis in acute myeloid leukemia von Šestáková, Šárka, Šálek, Cyril, Kundrát, Dávid, Cerovská, Ela, Vydra, Jan, Ježíšková, Ivana, Folta, Adam, Mayer, Jiří, Cetkovský, Petr, Remešová, Hana

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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR von Robesova, Blanka, Drncova, Marie, Folta, Adam, Krejci, Marta, Folber, Frantisek, Sustkova, Zuzana, Mayer, Jiri, Jeziskova, Ivana

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Mutations in myeloid transcription factors and activated signaling genes predict chronic myeloid leukemia outcomes von Perusini, Maria Agustina, Žáčková, Daniela, Kim, Taehyung, Pagnano, Katia, Pavlovsky, Carolina, Ježíšková, Ivana, Kvetková, Anežka, Jurček, Tomáš, Kim, Jaeyoon, Yoo, Youngseok, Yi, Seongyoon, Lee, Hyewon, Kim, Kyoung Ha, Chang, Myunghee, Capo-Chichi, Jose-Mario, Medeiros, Jessie J. F., Arruda, Andrea, Minden, Mark, Zhang, Zhaolei, Abelson, Sagi, Mayer, Jiri, Hwan Kim, Dennis Dong

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Clinical efficacy and safety of first‐line nilotinib or imatinib therapy in patients with chronic myeloid leukemia—Nationwide real life data von Belohlavkova, Petra, Zackova, Daniela, Klamova, Hana, Faber, Edgar, Karas, Michal, Stejskal, Lukas, Cmunt, Eduard, Cerna, Olga, Jeziskova, Ivana, Machova Polakova, Katerina, Zak, Pavel, Jurkova, Tereza, Chrapava, Marika, Mayer, Jiri

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A validation study of potential prognostic DNA methylation biomarkers in patients with acute myeloid leukemia using a custom DNA methylation sequencing panel von Šestáková, Šárka, Cerovská, Ela, Šálek, Cyril, Kundrát, Dávid, Ježíšková, Ivana, Folta, Adam, Mayer, Jiří, Ráčil, Zdeněk, Cetkovský, Petr, Remešová, Hana

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Distribution of mutations in DNMT3A gene and the suitability of mutations in R882 codon for MRD monitoring in patients with AML von Jeziskova, Ivana, Musilova, Milena, Culen, Martin, Foltankova, Veronika, Dvorakova, Dana, Mayer, Jiri, Racil, Zdenek

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The influence of mutational status and biological characteristics of acute myeloid leukemia on xenotransplantation outcomes in NOD SCID gamma mice von Culen, Martin, Kosarova, Zdenka, Jeziskova, Ivana, Folta, Adam, Chovancova, Jana, Loja, Tomas, Tom, Nikola, Bystry, Vojtech, Janeckova, Veronika, Dvorakova, Dana, Mayer, Jiri, Racil, Zdenek

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P669: ANALYSIS OF FACTORS INFLUENCING THE DECISION TO STOP TKI TREATMENT IN CML PATIENTS IN DEEP MOLECULAR RESPONSE von Semerad, Lukas, Žáčková, Daniela, Belohlavkova, Petra, Voglova, Jaroslava, Žák, Pavel, Faber, Edgar, Papajik, Tomas, Skoumalova, Ivana, Karas, Michal, Jindra, Pavel, Klamová, Hana, Salek, Cyril, Srbová, Dana, Zizkova, Hana, Stejskal, Lukas, Cerna, Olga, Cmunt, Eduard, Cicatkova, Petra, Kvetkova, Anezka, Hornak, Tomas, Jeziskova, Ivana, Jurcek, Tomas, Weinbergerová, Barbora, Prochazkova, Jirina, Machova Polakova, Katerina, Svobodnik, Adam, Stepanova, Radka, Mayer, Jiri

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Palbociclib and Ponatinib Suppress Acute Myeloid Leukemia in Patient-Derived Xenograft von Busa, Daniel, Loja, Tomas, Jeziskova, Ivana, Folta, Adam, Mayer, Jiri, Culen, Martin

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Methscore As a New Prognostic Tool for Complex DNA Methylation Changes Assessment in Patients with Acute Myeloid Leukemia von Sestakova, Sarka, Šálek, Cyril, Kundrát, Dávid, Ježíšková, Ivana, Mayer, Jiří, Ráčil, Zdeněk, Cetkovský, Petr, Remešová, Hana

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A Comparison of Two Standardized Quantitative RT-PCRs with CE IVD Kit for Digital PCR in CML Patients with Different Level of BCR-ABL1 Transcripts von Folta, Adam, Jurcek, Tomas, Kubesova, Blanka, Zackova, Daniela, Mayer, Jiri, Jeziskova, Ivana

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Effective NPM1 plasmid standards selection for minimal/measurable residual disease monitoring in acute myeloid leukemia von Folta, Adam, Sasinkova, Marketa, Durinikova, Anna, Drncova, Marie, Weinbergerova, Barbora, Mayer, Jiri, Jeziskova, Ivana

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New Pattern of Emerging Somatic Mutations in Optimal Responders Following Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukemia Patients Evidenced from Mutational Kinetic A... von Gupta, Gopila, Chiu, May, Al-Shaibani, Eshrak, Perusini, Maria Agustina, Lucero, Josephine, Zackova, Daniela, Jeziskova, Ivana, Kvetkova, Anezka, Jurcek, Tomas, Kim, Jaeyoon John, Pyne, Danielle, Travas, Anthea, Ambalavanan, Amirthagowri, Mayer, Jiri, Medeiros, Jessie, Abelson, Sagi, Kim, Dennis Dong Hwan

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Clonal hierarchy of main molecular lesions in acute myeloid leukaemia von Herudkova, Zdenka, Culen, Martin, Folta, Adam, Jeziskova, Ivana, Cerna, Jana, Loja, Tomas, Tom, Nikola, Smejkal, Jiri, Semerad, Lukas, Dvorakova, Dana, Mayer, Jiri, Racil, Zdenek

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Real World Population- Based Data from Nationwide Registry Support the Existence of Accelerated Phase in Newly Diagnosed Chronic Myeloid Leukemia (CML) Patients Even in Tyrosine Ki... von Hornak, Tomas, Mayer, Jiri, Cicatkova, Petra, Semerad, Lukas, Kvetkova, Anezka, Klamova, Hana, Faber, Edgar, Belohlavkova, Petra, Karas, Michal, Stejskal, Lukas, Cmunt, Eduard, Cerna, Olga, Srbova, Dana, Zizkova, Hana, Vrablova, Lucia, Skoumalova, Ivana, Voglova, Jaroslava, Jurkova, Tereza, Chrapava, Marika, Jurcek, Tomas, Jeziskova, Ivana, Jarosova, Marie, Machova Polakova, Katerina, Papajik, Tomas, Zak, Pavel, Jindra, Pavel, Zackova, Daniela

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Somatic Mutations in Myeloid Transcription Factors and in Activated Signaling Pathway, but Not in Epigenetic Modifier Pathway, Predict the Risk of Treatment Failure and Progression... von Kim, Taehyung, Žácková, Daniela, Ježíšková, Ivana, Kvetková, Anežka, Jurček, Tomáš, Yoo, Young Seok, Lee, Hyewon, Kim, Kyoung Ha, Chang, Myung Hee, Yi, Seong Yoon, Medeiros, Jessie J.F., Abelson, Sagi, Kim, Dennis

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Final Report: Somatic Mutations and HMGCLL1 Haplotype Are Not Associated with Molecular Relapse-Free Survival in Patients with Chronic Myeloid Leukemia Who Attempt Treatment-Free R... von Perusini, Maria Agustina, Pagnano, Katia, Pavlovsky, Carolina, Moiraghi, Beatriz, Varela, Ana, Bianchini, Michele, Fava, Carmen, Mayer, Jiří, Žáčková, Daniela, Kvetková, Anežka, Jurček, Tomáš, Ježíšková, Ivana, Lopes, Ana Beatriz Pascoal, Oliveira, Gislaine Borba, De Souza, Carmino, Ambalavanan, Amirthagowri, Travas, Anthea, Kim, Jaeyoon John, Pyne, Danielle, Medeiros, Jessie, Abelson, Sagi, Kim, Dennis Dong Hwan

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De novo accelerated phase of chronic myeloid leukemia should be recognized even in the era of tyrosine kinase inhibitors von Hornak, Tomas, Mayer, Jiri, Cicatkova, Petra, Semerad, Lukas, Kvetkova, Anezka, Klamova, Hana, Faber, Edgar, Belohlavkova, Petra, Karas, Michal, Stejskal, Lukas, Cmunt, Eduard, Cerna, Olga, Srbova, Dana, Zizkova, Hana, Vrablova, Lucia, Skoumalova, Ivana, Voglova, Jaroslava, Jurkova, Tereza, Chrapava, Marika, Jurcek, Tomas, Jeziskova, Ivana, Jarosova, Marie, Machova Polakova, Katerina, Papajik, Tomas, Zak, Pavel, Jindra, Pavel, Zackova, Daniela

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