Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma von Tsang, Tiffany, Posimo, Jessica M., Gudiel, Andrea A., Cicchini, Michelle, Feldser, David M., Brady, Donita C.

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Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism von Chung, Clive Yik-Sham, Posimo, Jessica M., Lee, Sumin, Tsang, Tiffany, Davis, Julianne M., Brady, Donita C., Chang, Christopher J.

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Synergistic stress exacerbation in hippocampal neurons: Evidence favoring the dual-hit hypothesis of neurodegeneration von Heinemann, Scott D., Posimo, Jessica M., Mason, Daniel M., Hutchison, Daniel F., Leak, Rehana K.

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Neocortex and allocortex respond differentially to cellular stress in vitro and aging in vivo von Posimo, Jessica M, Titler, Amanda M, Choi, Hailey J H, Unnithan, Ajay S, Leak, Rehana K

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Inhibition of BCL2 Family Members Increases the Efficacy of Copper Chelation in BRAFV600E-Driven Melanoma von Kim, Ye-Jin, Tsang, Tiffany, Anderson, Grace R., Posimo, Jessica M., Brady, Donita C.

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Loss of p19Arf promotes fibroblast survival during leucine deprivation von Roby, Kerry C, Lieberman, Allyson, Kim, Bang-Jin, Rodríguez, Nicole Zaragoza, Posimo, Jessica M, Tsang, Tiffany, Verginadis, Ioannis I, Puré, Ellen, Brady, Donita C, Koumenis, Constantinos, Ryeom, Sandra

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CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation von Rasool, Reyaz Ur, Natesan, Ramakrishnan, Deng, Qu, Aras, Shweta, Lal, Priti, Sander Effron, Samuel, Mitchell-Velasquez, Erick, Posimo, Jessica M, Carskadon, Shannon, Baca, Sylvan C, Pomerantz, Mark M, Siddiqui, Javed, Schwartz, Lauren E, Lee, Daniel J, Palanisamy, Nallasivam, Narla, Goutham, Den, Robert B, Freedman, Matthew L, Brady, Donita C, Asangani, Irfan A

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BRAFV600E-Driven Lung Adenocarcinoma Requires Copper to Sustain Autophagic Signaling and Processing von Tsang, Tiffany, Gu, Xingxing, Davis, Caroline I, Posimo, Jessica M, Miller, Zoey A, Brady, Donita C

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Copper chaperone ATOX1 is required for MAPK signaling and growth in BRAF mutation-positive melanoma von Kim, Ye-Jin, Bond, Gavin J, Tsang, Tiffany, Posimo, Jessica M, Busino, Luca, Brady, Donita C

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α-synucleinopathy exerts sex-dimorphic effects on the multipurpose DNA repair/redox protein APE1 in mice and humans von Miner, Kristin M., Jamenis, Anuj S., Bhatia, Tarun N., Clark, Rachel N., Rajasundaram, Dhivyaa, Sauvaigo, Sylvie, Mason, Daniel M., Posimo, Jessica M., Abraham, Nevil, DeMarco, Brett A., Hu, Xiaoming, Stetler, R. Anne, Chen, Jun, Sanders, Laurie H., Luk, Kelvin C., Leak, Rehana K.

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YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma von Rivera-Reyes, Adrian, Ye, Shuai, E. Marino, Gloria, Egolf, Shaun, E. Ciotti, Gabrielle, Chor, Susan, Liu, Ying, Posimo, Jessica M., Park, Paul M. C., Pak, Koreana, Babichev, Yael, Sostre-Colón, Jaimarie, Tameire, Feven, Leli, Nektaria Maria, Koumenis, Constantinos, C. Brady, Donita, Mancuso, Anthony, Weber, Kristy, Gladdy, Rebecca, Qi, Jun, Eisinger-Mathason, T. S. Karin

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Astrocyte plasticity revealed by adaptations to severe proteotoxic stress von Titler, Amanda M, Posimo, Jessica M, Leak, Rehana K

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Astrocytes Surviving Severe Stress Can Still Protect Neighboring Neurons from Proteotoxic Injury von Gleixner, Amanda M., Posimo, Jessica M., Pant, Deepti B., Henderson, Matthew P., Leak, Rehana K.

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N-Acetyl cysteine prevents synergistic, severe toxicity from two hits of oxidative stress von Unnithan, Ajay S., Jiang, Yiran, Rumble, Jennifer L., Pulugulla, Sree H., Posimo, Jessica M., Gleixner, Amanda M., Leak, Rehana K.

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Heat shock protein responses to aging and proteotoxicity in the olfactory bulb von Crum, Tyler S., Gleixner, Amanda M., Posimo, Jessica M., Mason, Daniel M., Broeren, Matthew T., Heinemann, Scott D., Wipf, Peter, Brodsky, Jeffrey L., Leak, Rehana K.

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Heat shock protein defenses in the neocortex and allocortex of the telencephalon von Posimo, Jessica M, Weilnau, Justin N, Gleixner, Amanda M, Broeren, Matthew T, Weiland, Nicole L, Brodsky, Jeffrey L, Wipf, Peter, Leak, Rehana K

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Viability assays for cells in culture von Posimo, Jessica M, Unnithan, Ajay S, Gleixner, Amanda M, Choi, Hailey J, Jiang, Yiran, Pulugulla, Sree H, Leak, Rehana K

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Correction: Neocortex and Allocortex Respond Differentially to Cellular Stress In Vitro and Aging In Vivo von Posimo, Jessica M., Titler, Amanda M., Choi, Hailey J. H., Unnithan, Ajay S., Leak, Rehana K.

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Rescue from a two hit, high-throughput model of neurodegeneration with N-acetyl cysteine von Unnithan, Ajay S., Choi, Hailey J.H., Titler, Amanda M., Posimo, Jessica M., Leak, Rehana K.

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Abstract 1262: Targeting transcriptional addiction in anti-androgen refractory castration-resistant prostate cancer von Rasool, Reyaz ur, Natesan, Ramakrishnan, Deng, Qu, Aras, Shweta, Effron, Samuel Sander, Velasquez, Erick Mitchell, Posimo, Jessica M., Lal, Priti, Brady, Donita C., Asangani, Irfan A.

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