B50 TUBERCULOSIS: CASE REPORTS: Pott's Disease, A Diagnosis That Should Not Be Missed von Jessamy, K, Kaul, V, Ojevwe, F, Anozie, O, Shepherd, Z

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Targeting glutamine transport to suppress melanoma cell growth von Wang, Qian, Beaumont, Kimberley A., Otte, Nicholas J., Font, Josep, Bailey, Charles G., Geldermalsen, Michelle, Sharp, Danae M., Tiffen, Jessamy C., Ryan, Renae M., Jormakka, Mika, Haass, Nikolas K., Rasko, John E.J., Holst, Jeff

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POT1 loss-of-function variants predispose to familial melanoma von Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J, Aoude, Lauren G, Quesada, Víctor, Ding, Zhihao, Pooley, Karen A, Pritchard, Antonia L, Tiffen, Jessamy C, Petljak, Mia, Palmer, Jane M, Symmons, Judith, Johansson, Peter, Stark, Mitchell S, Gartside, Michael G, Snowden, Helen, Montgomery, Grant W, Martin, Nicholas G, Liu, Jimmy Z, Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M, Dunning, Alison M, Keane, Thomas M, López-Otín, Carlos, Gruis, Nelleke A, Hayward, Nicholas K, Bishop, D Timothy, Newton-Bishop, Julia A, Adams, David J

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The Epigenetic Regulator I-BET151 Induces BIM-Dependent Apoptosis and Cell Cycle Arrest of Human Melanoma Cells von Gallagher, Stuart J., Mijatov, Branka, Gunatilake, Dilini, Tiffen, Jessamy C., Gowrishankar, Kavitha, Jin, Lei, Pupo, Gulietta M., Cullinane, Carleen, Prinjha, Rab K., Smithers, Nicholas, McArthur, Grant A., Rizos, Helen, Hersey, Peter

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Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes von Tiffen, Jessamy C, Gunatilake, Dilini, Gallagher, Stuart J, Gowrishankar, Kavitha, Heinemann, Anja, Cullinane, Carleen, Dutton-Regester, Ken, Pupo, Gulietta M, Strbenac, Dario, Yang, Jean Y, Madore, Jason, Mann, Graham J, Hayward, Nicholas K, McArthur, Grant A, Filipp, Fabian V, Hersey, Peter

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HDAC inhibitors restore BRAF‐inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma von Gallagher, Stuart J., Gunatilake, Dilini, Beaumont, Kimberley A., Sharp, Danae M., Tiffen, Jessamy C., Heinemann, Anja, Weninger, Wolfgang, Haass, Nikolas K., Wilmott, James S., Madore, Jason, Ferguson, Peter M., Rizos, Helen, Hersey, Peter

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Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling von Heinemann, Anja, Cullinane, Carleen, De Paoli-Iseppi, Ricardo, Wilmott, James S, Gunatilake, Dilini, Madore, Jason, Strbenac, Dario, Yang, Jean Y, Gowrishankar, Kavitha, Tiffen, Jessamy C, Prinjha, Rab K, Smithers, Nicholas, McArthur, Grant A, Hersey, Peter, Gallagher, Stuart J

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Valuing nature: lessons learned and future research directions von Turner, R.Kerry, Paavola, Jouni, Cooper, Philip, Farber, Stephen, Jessamy, Valma, Georgiou, Stavros

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Lancet COVID-19 Commission Statement on the occasion of the 75th session of the UN General Assembly von Sachs, Jeffrey D, Abdool Karim, Salim, Aknin, Lara, Allen, Joseph, Brosbøl, Kirsten, Cuevas Barron, Gabriela, Daszak, Peter, Espinosa, María Fernanda, Gaspar, Vitor, Gaviria, Alejandro, Haines, Andy, Hotez, Peter, Koundouri, Phoebe, Larraín Bascuñán, Felipe, Lee, Jong-Koo, Pate, Muhammad, Polman, Paul, Reddy, Srinath, Serageldin, Ismail, Shah, Raj, Thwaites, John, Vike-Freiberga, Vaira, Wang, Chen, Were, Miriam Khamadi, Xue, Lan, Zhu, Min, Bahadur, Chandrika, Bottazzi, Maria Elena, Ben Amor, Yanis, Barredo, Lauren, Karadag Caman, Ozge, Lafortune, Guillaume, Torres, Emma, Ethridge, Ismini, Bartels, Juliana G E

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Co‐targeting bromodomain and extra‐terminal proteins and MCL1 induces synergistic cell death in melanoma von Tseng, Hsin‐Yi, Dreyer, Jan, Emran, Abdullah Al, Gunatilake, Dilini, Pirozyan, Mehdi, Cullinane, Carleen, Dutton‐Regester, Ken, Rizos, Helen, Hayward, Nicholas K., McArthur, Grant, Hersey, Peter, Tiffen, Jessamy, Gallagher, Stuart

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Achieving justice in implementation: the Lancet Commission on Evidence-Based Implementation in Global Health von Peterson, Herbert B, Dube, Queen, Lawn, Joy E, Haidar, Joumana, Bagenal, Jessamy, Horton, Richard

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Chromo-pancreatoscopy for preoperative evaluation of main duct intraductal pancreatic mucinous neoplasm von Kadkhodayan, Kambiz, Viana, Artur, Singh, Sanmeet, Kegan, Jessamy, Amawi, Yusuf, Jain, Deepanshu, Yang, Dennis, Arain, Mustafa, Cosgrove, Natalie, Shayan, Irani, Hasan, Muhammad K.

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Landslide Hazard Assessment for National Rail Network von Freeborough, K.A., Diaz Doce, D., Lethbridge, R., Jessamy, G., Dashwood, C., Pennington, C., Reeves, H.J.

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Abstract 20: POT1 mutations predispose to familial melanoma von Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J., Aoude, Lauren G., Quesada, Victor, Ding, Zhihao, Pooley, Karen A., Pritchard, Antonia L., Tiffen, Jessamy C., Petljak, Mia, Palmer, Jane M., Symmons, Judith, Johansson, Peter, Stark, Mitchell S., Gartside, Michael G., Snowden, Helen, Montgomery, Grant W., Martin, Nicholas G., Liu, Jimmy Z., Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M., Dunning, Alison M., Keane, Thomas M., Lopez-Otin, Carlos, Gruis, Nelleke A., Hayward, Nicholas K., Bishop, D. Timothy, Newton-Bishop, Julia A., Adams, David J.

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Economic Reasons for Conserving Wild Nature von Balmford, Andrew, Bruner, Aaron, Cooper, Philip, Costanza, Robert, Farber, Stephen, Green, Rhys E., Jenkins, Martin, Jefferiss, Paul, Jessamy, Valma, Madden, Joah, Munro, Kat, Myers, Norman, Naeem, Shahid, Paavola, Jouni, Rayment, Matthew, Rosendo, Sergio, Roughgarden, Joan, Trumper, Kate, Turner, R. Kerry

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POT1 loss-of-function variants predispose to familial melanoma von Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J, Aoude, Lauren G, Quesada, Víctor, Ding, Zhihao, Pooley, Karen A, Pritchard, Antonia L, Tiffen, Jessamy C, Petljak, Mia, Palmer, Jane M, Symmons, Judith, Johansson, Peter, Stark, Mitchell S, Gartside, Michael G, Snowden, Helen, Montgomery, Grant W, Martin, Nicholas G, Liu, Jimmy Z, Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M, Dunning, Alison M, Keane, Thomas M, López-Otín, Carlos, Gruis, Nelleke A, Hayward, Nicholas K, Bishop, D Timothy, Newton-Bishop, Julia A, Adams, David J

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