MTXPK.org: A Clinical Decision Support Tool Evaluating High‐Dose Methotrexate Pharmacokinetics to Inform Post‐Infusion Care and Use of Glucarpidase von Taylor, Zachary L., Mizuno, Tomoyuki, Punt, Nieko C., Baskaran, Balaji, Navarro Sainz, Adriana, Shuman, William, Felicelli, Nicholas, Vinks, Alexander A., Heldrup, Jesper, Ramsey, Laura B.

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Response-Guided Induction Therapy in Pediatric Acute Myeloid Leukemia With Excellent Remission Rate von ABRAHAMSSON, Jonas, FORESTIER, Erik, HELDRUP, Jesper, JAHNUKAINEN, Kirsi, JONSSON, Olafur G, LAUSEN, Birgitte, PALLE, Josefine, ZELLER, Bernward, HASLE, Henrik

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Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia von Paulsson, Kajsa, Forestier, Erik, Lilljebjörn, Henrik, Heldrup, Jesper, Behrendtz, Mikael, Young, Bryan D., Johansson, Bertil, Rowley, Janet D.

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Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia von Borssén, Magnus, Palmqvist, Lars, Karrman, Kristina, Abrahamsson, Jonas, Behrendtz, Mikael, Heldrup, Jesper, Forestier, Erik, Roos, Göran, Degerman, Sofie

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Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia von Paulsson, Kajsa, Horvat, Andrea, Strömbeck, Bodil, Nilsson, Fredrik, Heldrup, Jesper, Behrendtz, Mikael, Forestier, Erik, Andersson, Anna, Fioretos, Thoas, Johansson, Bertil

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Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study von Sandahl, Julie Damgaard, Kjeldsen, Eigil, Abrahamsson, Jonas, Ha, Shau-Yin, Heldrup, Jesper, Jahnukainen, Kirsi, Jónsson, Ólafur G., Lausen, Birgitte, Palle, Josefine, Zeller, Bernward, Forestier, Erik, Hasle, Henrik

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Trisomy 8 in pediatric acute myeloid leukemia: A NOPHO-AML study von Laursen, Anne Cathrine Lund, Sandahl, Julie Damgaard, Kjeldsen, Eigil, Abrahamsson, Jonas, Asdahl, Peter, Ha, Shau-Yin, Heldrup, Jesper, Jahnukainen, Kirsi, Jónsson, Ólafur G., Lausen, Birgitte, Palle, Josefine, Zeller, Bernward, Forestier, Erik, Hasle, Henrik

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Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries von Wennström, Lovisa, Edslev, Pernille Wendtland, Abrahamsson, Jonas, Nørgaard, Jan Maxwell, Fløisand, Yngvar, Forestier, Erik, Gustafsson, Göran, Heldrup, Jesper, Hovi, Liisa, Jahnukainen, Kirsi, Jonsson, Olafur Gisli, Lausen, Birgitte, Palle, Josefine, Zeller, Bernward, Holmberg, Erik, Juliusson, Gunnar, Stockelberg, Dick, Hasle, Henrik

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Molecular Signatures in Childhood Acute Leukemia and Their Correlations to Expression Patterns in Normal Hematopoietic Subpopulations von Anna Andersson, Tor Olofsson, David Lindgren, Nilsson, Björn, Cecilia Ritz, Patrik Edén, Carin Lassen, Johan Råde, Magnus Fontes, Helena Mörse, Jesper Heldrup, Mikael Behrendtz, Mitelman, Felix, Höglund, Mattias, Johansson, Bertil, Thoas Fioretos

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Simultaneous determination of folate and methotrexate metabolites in serum by LC-MS/MS during high-dose methotrexate therapy von Hansson, Karin, Orrling, Henrik, Blomgren, Anders, Isaksson, Anders, Schliamser, Gloria, Heldrup, Jesper, Pronk, Cornelis Jan

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Hypoalbuminemia in children with acute lymphoblastic leukemia: relation to asparaginase therapy and impact on high dose methotrexate elimination von Christensen, Sophie Rex, Jensen, Christina Friis, Heldrup, Jesper, Taylor, Zachary, Ramsey, Laura B., Rosthøj, Steen

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Consensus Guideline for Use of Glucarpidase in Patients with High‐Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance von Ramsey, Laura B., Balis, Frank M., O'Brien, Maureen M., Schmiegelow, Kjeld, Pauley, Jennifer L., Bleyer, Archie, Widemann, Brigitte C., Askenazi, David, Bergeron, Sharon, Shirali, Anushree, Schwartz, Stefan, Vinks, Alexander A., Heldrup, Jesper

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Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004 von Hasle, Henrik, Abrahamsson, Jonas, Forestier, Erik, Ha, Shau-Yin, Heldrup, Jesper, Jahnukainen, Kirsi, Jónsson, Ólafur Gísli, Lausen, Birgitte, Palle, Josefine, Zeller, Bernward

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Extracorporeal Treatment for Methotrexate Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup von Ghannoum, Marc, Roberts, Darren M, Goldfarb, David S, Heldrup, Jesper, Anseeuw, Kurt, Galvao, Tais F, Nolin, Thomas D, Hoffman, Robert S, Lavergne, Valery, Meyers, Paul, Gosselin, Sophie, Botnaru, Tudor, Mardini, Karine, Wood, David M

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Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing von Ibarra, Manuel, Combs, Ryan, Taylor, Zachary L., Ramsey, Laura B., Mikkelsen, Torben, Buddington, Randal K., Heldrup, Jesper, Barreto, Jason N., Guscott, Martin, Lowe, Jennifer, Hurmiz, Charles, Marada, Suresh, Howard, Scott C., Schaiquevich, Paula

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Plasma creatinine as predictor of delayed elimination of high‐dose methotrexate in childhood acute lymphoblastic leukemia: A Danish population‐based study von Schmidt, Diana, Kristensen, Kim, Schroeder, Henrik, Wehner, Peder Skov, Rosthøj, Steen, Heldrup, Jesper, Damsgaard, Linn, Schmiegelow, Kjeld, Mikkelsen, Torben Stamm

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Delayed elimination of high‐dose methotrexate and use of carboxypeptidase G2 in pediatric patients during treatment for acute lymphoblastic leukemia von Svahn, Thommy, Mellgren, Karin, Harila‐Saari, Arja, Åsberg, Ann, Kanerva, Jukka, Jónsson, Ólafur, Vaitkeviciene, Goda, Stamm Mikkelssen, Torben, Schmiegelow, Kjeld, Heldrup, Jesper

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The DNA methylome of pediatric acute lymphoblastic leukemia von Davidsson, Josef, Lilljebjörn, Henrik, Andersson, Anna, Veerla, Srinivas, Heldrup, Jesper, Behrendtz, Mikael, Fioretos, Thoas, Johansson, Bertil

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Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status von ANDERSSON, A, RITZ, C, BEHRENDTZ, M, HÖGLUND, M, JOHANSSON, B, FIORETOS, T, LINDGREN, D, EDEN, P, LASSEN, C, HELDRUP, J, OLOFSSON, T, RADE, J, FONTES, M, PORWIT-MACDONALD, A

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Efficacy and Toxicity of Intrathecal Liposomal Cytarabine in First-line Therapy of Childhood Acute Lymphoblastic Leukemia von Levinsen, Mette, Harila-Saari, Arja, Grell, Kathrine, Jonsson, Olafur Gisli, Taskinen, Mervi, Abrahamsson, Jonas, Vettenranta, Kim, Åsberg, Ann, Risteli, Juha, Heldrup, Jesper, Schmiegelow, Kjeld

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