Tumor-initiating capacity of CD138− and CD138+ tumor cells in the 5T33 multiple myeloma model von Van Valckenborgh, E, Matsui, W, Agarwal, P, Lub, S, Dehui, X, De Bruyne, E, Menu, E, Empsen, C, van Grunsven, L, Agarwal, J, Wang, Q, Jernberg-Wiklund, H, Vanderkerken, K

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Tracing leachates at waste sites using geophysical and geochemical modelling von OLOFSSON, Bo, JERNBERG, Hillevie, ROSENQVIST, Andreas

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Taming the cancer cell von Jernberg Wiklund, H., Westermark, B.

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Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy von Karlsson, S C H, Lindqvist, A C, Fransson, M, Paul-Wetterberg, G, Nilsson, B, Essand, M, Nilsson, K, Frisk, P, Jernberg-Wiklund, H, Loskog, S I A

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SUMO‐modified insulin‐like growth factor 1 receptor (IGF‐1R) increases cell cycle progression and cell proliferation von Lin, Yingbo, Liu, Hongyu, Waraky, Ahmed, Haglund, Felix, Agarwal, Prasoon, Jernberg‐Wiklund, Helena, Warsito, Dudi, Larsson, Olle

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Taming the cancer cell: Introduction von Jernberg Wiklund, Helena, Westermark, Bengt

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EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions von Alzrigat, Mohammad, Párraga, Alba Atienza, Agarwal, Prasoon, Zureigat, Hadil, Österborg, Anders, Nahi, Hareth, Ma, Anqi, Jin, Jian, Nilsson, Kenneth, Öberg, Fredrik, Kalushkova, Antonia, Jernberg-Wiklund, Helena

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Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy von Karlsson, S C H, Lindqvist, A C, Fransson, M, Paul-wetterberg, G, Nilsson, B, Essand, M, Nilsson, K, Frisk, P, Jernberg-wiklund, H, Loskog, S I A

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Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cells von PETTERSSON, M, JERNBERG-WIKLUND, H, LARSSON, L.-G, SUNDSTRÖM, C, TSUJIMOTO, Y, NILSSON, K

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Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia von Mansouri, Larry, Sutton, Lesley-Ann, Ljungström, Viktor, Bondza, Sina, Arngården, Linda, Bhoi, Sujata, Larsson, Jimmy, Cortese, Diego, Kalushkova, Antonia, Plevova, Karla, Young, Emma, Gunnarsson, Rebeqa, Falk-Sörqvist, Elin, Lönn, Peter, Muggen, Alice F, Yan, Xiao-Jie, Sander, Birgitta, Enblad, Gunilla, Smedby, Karin E, Juliusson, Gunnar, Belessi, Chrysoula, Rung, Johan, Chiorazzi, Nicholas, Strefford, Jonathan C, Langerak, Anton W, Pospisilova, Sarka, Davi, Frederic, Hellström, Mats, Jernberg-Wiklund, Helena, Ghia, Paolo, Söderberg, Ola, Stamatopoulos, Kostas, Nilsson, Mats, Rosenquist, Richard

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Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma von Borgenvik, Anna, Holmberg, Karl O, Bolin, Sara, Zhao, Miao, Savov, Vasil, Rosén, Gabriela, Hutter, Sonja, Garancher, Alexandra, Rahmanto, Aldwin Suryo, Bergström, Tobias, Olsen, Thale Kristin, Mainwaring, Oliver J, Sattanino, Damiana, Verbaan, Annemieke D, Rusert, Jessica M, Sundström, Anders, Bravo, Mar Ballester, Dang, Yonglong, Wenz, Amelie S, Richardson, Stacey, Fotaki, Grammatiki, Hill, Rebecca M, Dubuc, Adrian M, Kalushkova, Antonia, Remke, Marc, Čančer, Matko, Jernberg-Wiklund, Helena, Giraud, Géraldine, Chen, Xingqi, Taylor, Michael D, Sangfelt, Olle, Clifford, Steven C, Schüller, Ulrich, Wechsler-Reya, Robert J, Weishaupt, Holger, Swartling, Fredrik J

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Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential t... von Agarwal, Prasoon, Alzrigat, Mohammad, Párraga, Alba Atienza, Enroth, Stefan, Singh, Umashankar, Ungerstedt, Johanna, Österborg, Anders, Brown, Peter J, Ma, Anqi, Jin, Jian, Nilsson, Kenneth, Öberg, Fredrik, Kalushkova, Antonia, Jernberg-Wiklund, Helena

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One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies von Kalushkova, Antonia, Nylund, Patrick, Párraga, Alba Atienza, Lennartsson, Andreas, Jernberg-Wiklund, Helena

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Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9 von Deng, Hua, Lin, Yingbo, Badin, Margherita, Vasilcanu, Daiana, Strömberg, Thomas, Jernberg-Wiklund, Helena, Sehat, Bita, Larsson, Olle

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Polycomb target genes are silenced in multiple myeloma von Kalushkova, Antonia, Fryknäs, Mårten, Lemaire, Miguel, Fristedt, Charlotte, Agarwal, Prasoon, Eriksson, Maria, Deleu, Sarah, Atadja, Peter, Osterborg, Anders, Nilsson, Kenneth, Vanderkerken, Karin, Oberg, Fredrik, Jernberg-Wiklund, Helena

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P01-24 The combination of the IGF-1 receptor inhibitor picropodophylin (PPP) and the BH3 mimetic ABT-737 has synergistic anti-myeloma activity von Bieghs, L, Maes, K, Van Valckenborgh, E, Menu, E, Johnsen, H.E, Nyegaard, M, Overgaard, M.T, Larson, O, Jernberg-Wiklund, H, Vanderkerken, K, De Bruyne, E

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The G(-248)A polymorphism in the promoter region of the Bax gene does not correlate with prognostic markers or overall survival in chronic lymphocytic leukemia von Skogsberg, Å, Tobin, G, Kröber, A, Kienle, D, Thunberg, U, Åleskog, A, Karlsson, K, Laurell, A, Merup, M, Vilpo, J, Sundström, C, Roos, G, Jernberg-Wiklund, H, Döhner, H, Nilsson, K, Stilgenbauer, S, Rosenquist, R

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The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomains von Alzrigat, Mohammad, Párraga, Alba Atienza, Majumder, Muntasir Mamun, Ma, Anqi, Jin, Jian, Österborg, Anders, Nahi, Hareth, Nilsson, Kenneth, Heckman, Caroline A, Öberg, Fredrik, Kalushkova, Antonia, Jernberg-Wiklund, Helena

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Sorafenib Has Potent Antitumor Activity against Multiple Myeloma In Vitro, Ex Vivo, and In Vivo in the 5T33MM Mouse Model von KHARAZIHA, Pedram, DE RAEVE, Hendrik, ZHIVOTOVSKY, Boris, JERNBERG-WIKLUND, Helena, GRANDER, Dan, CELSING, Fredrik, BJÖRKHOLM, Magnus, VANDERKERKEN, Karin, PANARETAKIS, Theocharis, FRISTEDT, Charlotte, QIAO LI, GRUBER, Astrid, JOHNSSON, Per, KOKARAKI, Georgia, PANZAR, Maria, LAANE, Edward, ÖSTERBORG, Anders

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IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells von Strömberg, Thomas, Ekman, Simon, Girnita, Leonard, Dimberg, Lina Y., Larsson, Olle, Axelson, Magnus, Lennartsson, Johan, Hellman, Ulf, Carlson, Kristina, Österborg, Anders, Vanderkerken, Karin, Nilsson, Kenneth, Jernberg-Wiklund, Helena

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