The Structural Basis of Pathogenic Subgenomic Flavivirus RNA (sfRNA) Production von Chapman, Erich G., Costantino, David A., Rabe, Jennifer L., Moon, Stephanie L., Wilusz, Jeffrey, Nix, Jay C., Kieft, Jeffrey S.

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Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors von Higa, Kelly C, Goodspeed, Andrew, Chavez, James S, De Dominici, Marco, Danis, Etienne, Zaberezhnyy, Vadym, Rabe, Jennifer L, Tenen, Daniel G, Pietras, Eric M, DeGregori, James

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New hypotheses derived from the structure of a flaviviral Xrn1-resistant RNA: Conservation, folding, and host adaptation von Kieft, Jeffrey S, Rabe, Jennifer L, Chapman, Erich G

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Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling von Pollyea, Daniel A, Harris, Chelsea, Rabe, Jennifer L, Hedin, Brenna R, De Arras, Lesly, Katz, Sigrid, Wheeler, Emily, Bejar, Rafael, Walter, Matthew J, Jordan, Craig T, Pietras, Eric M, Alper, Scott

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CD34 and EPCR coordinately enrich functional murine hematopoietic stem cells under normal and inflammatory conditions von Rabe, Jennifer L., Hernandez, Giovanny, Chavez, James S., Mills, Taylor S., Nerlov, Claus, Pietras, Eric M.

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PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress von Chavez, James S, Rabe, Jennifer L, Loeffler, Dirk, Higa, Kelly C, Hernandez, Giovanny, Mills, Taylor S, Ahmed, Nouraiz, Gessner, Rachel L, Ke, Zhonghe, Idler, Beau M, Niño, Katia E, Kim, Hyunmin, Myers, Jason R, Stevens, Brett M, Davizon-Castillo, Pavel, Jordan, Craig T, Nakajima, Hideaki, Ashton, John, Welner, Robert S, Schroeder, Timm, DeGregori, James, Pietras, Eric M

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Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis von Hernandez, Giovanny, Mills, Taylor S, Rabe, Jennifer L, Chavez, James S, Kuldanek, Susan, Kirkpatrick, Gregory, Noetzli, Leila, Jubair, Widian K, Zanche, Michelle, Myers, Jason R, Stevens, Brett M, Fleenor, Courtney J, Adane, Biniam, Dinarello, Charles A, Ashton, John, Jordan, Craig T, Di Paola, Jorge, Hagman, James R, Holers, V Michael, Kuhn, Kristine A, Pietras, Eric M

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hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition von Peddigari, Suresh, Li, Patrick Wai-Lun, Rabe, Jennifer L, Martin, Sandra L

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PU.1 Expression Defines Distinct Functional Activities in the Phenotypic HSC Compartment of a Murine Inflammatory Stress Model von Chavez, James S, Rabe, Jennifer L, Hernandez, Giovanny, Mills, Taylor S, Niño, Katia E, Davizon-Castillo, Pavel, Pietras, Eric M

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Zinc Finger Protein 521 Regulates Early Hematopoiesis through Cell-Extrinsic Mechanisms in the Bone Marrow Microenvironment von Fleenor, Courtney J., Arends, Tessa, Lei, Hong, Åhsberg, Josefine, Okuyama, Kazuki, Kuruvilla, Jacob, Cristobal, Susana, Rabe, Jennifer L., Pandey, Ahwan, Danhorn, Thomas, Straign, Desiree, Espinosa, Joaquin M., Warming, Søren, Pietras, Eric M., Sigvardsson, Mikael, Hagman, James R.

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IL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression von Rabe, Jennifer L, Gardner, Lori, Hunter, Rae, Fonseca, Jairo A, Dougan, Jodi, Gearheart, Christy M, Leibowitz, Michael S, Lee-Miller, Cathy, Baturin, Dmitry, Fosmire, Susan P, Zelasko, Susan E, Jones, Courtney L, Slansky, Jill E, Rupji, Manali, Dwivedi, Bhakti, Henry, Curtis J, Porter, Christopher C

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PU.1 is required to restrain myelopoiesis during chronic inflammatory stress von Chavez, James S, Rabe, Jennifer L, Niño, Katia E, Wells, Harrison H, Gessner, Rachel L, Mills, Taylor S, Hernandez, Giovanny, Pietras, Eric M

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Siglec-15 Promotes Evasion of Adaptive Immunity in B-cell Acute Lymphoblastic Leukemia von Pillsbury, Claire E, Dougan, Jodi, Rabe, Jennifer L, Fonseca, Jairo A, Zhou, Chengjing, Evans, Alyssa N, Abukharma, Hasan, Ichoku, Ona, Gonzalez-Flamenco, Gloria, Park, Sunita I, Aljudi, Ahmed, DeRyckere, Deborah, Castellino, Sharon M, Rafiq, Sarwish, Langermann, Solomon, Liu, Linda N, Henry, Curtis J, Porter, Christopher C

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Altered HSC fate underlies aberrant blood phenotypes in rheumatoid arthritis von Pietras, Eric, Hernandez, Giovanny, Kuldanek, Susan, Jennifer, Rabe, Kirkpatrick, Gregory, Noetzli, Leila, Acharya, Sumitra, Adane, Biniam, Jordan, Craig, DiPaola, Jorge, Holers, Michael, Banda, Nirmal

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Identification of a Hematopoietic Stem Cell Fraction That Retains Normal Function Following Chronic Inflammation von Rabe, Jennifer L, Hernandez, Giovanny, Pietras, Eric Martin

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Abstract 4151: Siglec-15 is a novel immunomodulatory effector of adaptive immune evasion in acute lymphoblastic leukemia von Pillsbury, Claire, Fonseca, Jairo A., Dougan, Jodi, Gardner, Lori, Rabe, Jennifer, Gearheart, Christy, Porter, Chris C.

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INTERLEUKIN-1 RESTRICTS HSC PROLIFERATION VIA A PU.1-DEPENDENT MECHANISM von Pietras, Eric, Rabe, Jennifer, Chavez, James, Higa, Kelly, Loeffler, Dirk, Mills, Taylor, Nerlov, Claus, Schroeder, Timm, DeGregori, James

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Abstract 4146: Calcineurin represses IL-12 secretion in acute lymphoblastic leukemia von Hunter, Rae, Fonseca, Jairo, Dougan, Jodi, Gardner, Lori A., Rabe, Jennifer, Rupji, Manali, Dwivedi, Bhakti, Henry, Curtis J., Porter, Christopher C.

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IL-1 Drives Clonal Hematopoiesis via Selective Induction of Growth Arrest in Normal HSC von Pietras, Eric, Rabe, Jennifer, Higa, Kelly, Chavez, James, Mills, Taylor, Nemkov, Travis, Nerlov, Claus, Dinarello, Charles, D'Alessandro, Angelo, DeGregori, James

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3137 - IL-1 Drives Clonal Hematopoiesis via Selective Induction of Growth Arrest in Normal HSC von Pietras, Eric, Rabe, Jennifer, Higa, Kelly, Chavez, James, Mills, Taylor, Nemkov, Travis, Nerlov, Claus, Dinarello, Charles, D'Alessandro, Angelo, DeGregori, James

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