Identifying compound efficacy targets in phenotypic drug discovery von Schirle, Markus, Jenkins, Jeremy L.

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Large-scale prediction and testing of drug activity on side-effect targets von Lounkine, Eugen, Keiser, Michael J., Whitebread, Steven, Mikhailov, Dmitri, Hamon, Jacques, Jenkins, Jeremy L., Lavan, Paul, Weber, Eckhard, Doak, Allison K., Côté, Serge, Shoichet, Brian K., Urban, Laszlo

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Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide von Fischer, Eric S., Böhm, Kerstin, Lydeard, John R., Yang, Haidi, Stadler, Michael B., Cavadini, Simone, Nagel, Jane, Serluca, Fabrizio, Acker, Vincent, Lingaraju, Gondichatnahalli M., Tichkule, Ritesh B., Schebesta, Michael, Forrester, William C., Schirle, Markus, Hassiepen, Ulrich, Ottl, Johannes, Hild, Marc, Beckwith, Rohan E. J., Harper, J. Wade, Jenkins, Jeremy L., Thomä, Nicolas H.

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Using Information from Historical High-Throughput Screens to Predict Active Compounds von Riniker, Sereina, Wang, Yuan, Jenkins, Jeremy L, Landrum, Gregory A

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Evidence-Based and Quantitative Prioritization of Tool Compounds in Phenotypic Drug Discovery von Wang, Yuan, Cornett, Allen, King, Fred J., Mao, Yi, Nigsch, Florian, Paris, C. Gregory, McAllister, Gregory, Jenkins, Jeremy L.

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DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery von Ye, Chaoyang, Ho, Daniel J., Neri, Marilisa, Yang, Chian, Kulkarni, Tripti, Randhawa, Ranjit, Henault, Martin, Mostacci, Nadezda, Farmer, Pierre, Renner, Steffen, Ihry, Robert, Mansur, Leandra, Keller, Caroline Gubser, McAllister, Gregory, Hild, Marc, Jenkins, Jeremy, Kaykas, Ajamete

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Ten simple rules to power drug discovery with data science von Ferrero, Enrico, Brachat, Sophie, Jenkins, Jeremy L., Marc, Philippe, Skewes-Cox, Peter, Altshuler, Robert C., Gubser Keller, Caroline, Kauffmann, Audrey, Sassaman, Erik K., Laramie, Jason M., Schoeberl, Birgit, Borowsky, Mark L., Stiefl, Nikolaus

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From in silico target prediction to multi-target drug design: Current databases, methods and applications von Koutsoukas, Alexios, Simms, Benjamin, Kirchmair, Johannes, Bond, Peter J., Whitmore, Alan V., Zimmer, Steven, Young, Malcolm P., Jenkins, Jeremy L., Glick, Meir, Glen, Robert C., Bender, Andreas

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Prediction of Biological Targets for Compounds Using Multiple-Category Bayesian Models Trained on Chemogenomics Databases von Nidhi, Glick, Meir, Davies, John W, Jenkins, Jeremy L

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Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK von Tan, Ceryl, Ginzberg, Miriam B., Webster, Rachel, Iyengar, Seshu, Liu, Shixuan, Papadopoli, David, Concannon, John, Wang, Yuan, Auld, Douglas S., Jenkins, Jeremy L., Rost, Hannes, Topisirovic, Ivan, Hilfinger, Andreas, Derry, W. Brent, Patel, Nish, Kafri, Ran

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Integrating high-content screening and ligand-target prediction to identify mechanism of action von Jenkins, Jeremy L, Feng, Yan, Young, Daniel W, Bender, Andreas, Hoyt, Jonathan, McWhinnie, Elizabeth, Chirn, Gung-Wei, Tao, Charles Y, Tallarico, John A, Labow, Mark, Mitchison, Timothy J

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Compound Activity Prediction with Dose-Dependent Transcriptomic Profiles and Deep Learning von Godinez, William J., Trifonov, Vladimir, Fang, Bin, Kuzu, Guray, Pei, Luying, Guiguemde, W. Armand, Martin, Eric J., King, Frederick J., Jenkins, Jeremy L., Skewes-Cox, Peter

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Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off-Target Effects from Chemical Structure von Bender, Andreas, Scheiber, Josef, Glick, Meir, Davies, John W., Azzaoui, Kamal, Hamon, Jacques, Urban, Laszlo, Whitebread, Steven, Jenkins, Jeremy L.

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Learning epistatic gene interactions from perturbation screens von Elmes, Kieran, Schmich, Fabian, Szczurek, Ewa, Jenkins, Jeremy, Beerenwinkel, Niko, Gavryushkin, Alex

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Pocket Crafter: a 3D generative modeling based workflow for the rapid generation of hit molecules in drug discovery von Shen, Lingling, Fang, Jian, Liu, Lulu, Yang, Fei, Jenkins, Jeremy L., Kutchukian, Peter S., Wang, He

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Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length von Liu, Shixuan, Ginzberg, Miriam Bracha, Patel, Nish, Hild, Marc, Leung, Bosco, Li, Zhengda, Chen, Yen-Chi, Chang, Nancy, Wang, Yuan, Tan, Ceryl, Diena, Shulamit, Trimble, William, Wasserman, Larry, Jenkins, Jeremy L, Kirschner, Marc W, Kafri, Ran

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Quantitative Prioritization of Tool Compounds for Phenotypic Screening von Wang, Yuan, Jenkins, Jeremy L.

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How Similar Are Similarity Searching Methods? A Principal Component Analysis of Molecular Descriptor Space von Bender, Andreas, Jenkins, Jeremy L, Scheiber, Josef, Sukuru, Sai Chetan K, Glick, Meir, Davies, John W

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Drug discovery: Rethinking cellular drug response von Jenkins, Jeremy L

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Systematic Chemogenetic Library Assembly von Canham, Stephen M., Wang, Yuan, Cornett, Allen, Auld, Douglas S., Baeschlin, Daniel K., Patoor, Maude, Skaanderup, Philip R., Honda, Ayako, Llamas, Luis, Wendel, Greg, Mapa, Felipa A., Aspesi, Peter, Labbé-Giguère, Nancy, Gamber, Gabriel G., Palacios, Daniel S., Schuffenhauer, Ansgar, Deng, Zhan, Nigsch, Florian, Frederiksen, Mathias, Bushell, Simon M., Rothman, Deborah, Jain, Rishi K., Hemmerle, Horst, Briner, Karin, Porter, Jeffery A., Tallarico, John A., Jenkins, Jeremy L.

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