Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening von Tan, Jenille, Martin, Scott E

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Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens von Fortin, Jean-Philippe, Tan, Jenille, Gascoigne, Karen E, Haverty, Peter M, Forrest, William F, Costa, Michael R, Martin, Scott E

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Abstract 73: Exploring arrayed synthetic CRISPR for functional genomic screening von Tan, Jenille M., Martin, Scott E.

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ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer von Vartanian, Steffan, Lee, James, Klijn, Christiaan, Gnad, Florian, Bagniewska, Maria, Schaefer, Gabriele, Zhang, Donglu, Tan, Jenille, Watson, Sara A, Liu, Liling, Chen, Honglin, Liang, Yuxin, Watanabe, Colin, Cuellar, Trinna, Kan, David, Hartmaier, Ryan J, Lau, Ted, Costa, Michael R, Martin, Scott E, Merchant, Mark, Haley, Benjamin, Stokoe, David

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Gene Trap Disruption of the Mouse Heparan Sulfate 6-O-Endosulfatase Gene, Sulf2 von Lum, David H., Tan, Jenille, Rosen, Steven D., Werb, Zena

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines von Mygland, Line, Brinch, Shoshy Alam, Strand, Martin Frank, Olsen, Petter Angell, Aizenshtadt, Aleksandra, Lund, Kaja, Solberg, Nina Therese, Lycke, Max, Thorvaldsen, Tor Espen, Espada, Sandra, Misaghian, Dorna, Page, Christian M., Agafonov, Oleg, Nygård, Ståle, Chi, Nai-Wen, Lin, Eva, Tan, Jenille, Yu, Yihong, Costa, Mike, Krauss, Stefan, Waaler, Jo

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Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate von Chang, Tsun-Kai, Lawrence, David A., Lu, Min, Tan, Jenille, Harnoss, Jonathan M., Marsters, Scot A., Liu, Peter, Sandoval, Wendy, Martin, Scott E., Ashkenazi, Avi

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Reproducible pharmacogenomic profiling of cancer cell line panels von Haverty, Peter M., Lin, Eva, Tan, Jenille, Yu, Yihong, Lam, Billy, Lianoglou, Steve, Neve, Richard M., Martin, Scott, Settleman, Jeff, Yauch, Robert L., Bourgon, Richard

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Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies von Newton, Kim, Matsumoto, Marissa L., Wertz, Ingrid E., Kirkpatrick, Donald S., Lill, Jennie R., Tan, Jenille, Dugger, Debra, Gordon, Nathaniel, Sidhu, Sachdev S., Fellouse, Frederic A., Komuves, Laszlo, French, Dorothy M., Ferrando, Ronald E., Lam, Cynthia, Compaan, Deanne, Yu, Christine, Bosanac, Ivan, Hymowitz, Sarah G., Kelley, Robert F., Dixit, Vishva M.

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Abstract 5388: Triple-threat: Inavolisib and giredestrant combine with palbociclib to achieve sustained cell cycle arrest in ER-positive breast cancer models von Marohl, Taylor, Tan, Jenille, Zhou, Wei, Guan, Jane, Carlos, Sandra Melo, Xie, Shiqi, Hafner, Marc, Metcalfe, Ciara

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Abstract 3141: Epiregulon infers single-cell transcription factor activity to dissect mechanisms of lineage plasticity and drug response von Wlodarczyk, Tomasz, Tan, Jenille, Seidel, Kerstin, Wu, Diana, Chen, Shang-Yang, Chlebowski, Aleksander, Keyes, Timothy, Guo, Yu, Lun, Aaron, Siebel, Christopher, Xie, Shiqi, Yao, Xiaosai

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Reproducible pharmacogenomics profiling of cancer cell line panels von Haverty, Peter M, Lin, Eva, Tan, Jenille, Yu, Yihong, Lam, Billy, Lianoglou, Steve, Neve, Richard M, Martin, Scott, Settleman, Jeff, Yauch, Robert L, Bourgon, Richard

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Abstract 944: Development of predictive and pharmacodynamic biomarker strategies for GDC-0425, a checkpoint kinase 1 inhibitor, in combination with gemcitabine von Mahrus, Sami, DuPree, Kelly, Kowanetz, Kaska, Tan, Jenille, Tremayne, Jarrod, Jakubiak, Diana, Haverty, Peter, Zhu, Yuda, Peale, Franklin, Blackwood, Elizabeth, Bourgon, Richard, Yauch, Robert, Lackner, Mark, Evangelista, Marie

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines von Mygland, Line, Mahmuda, Shoshy, Strand, Martin Frank, Olsen, Petter Angell, Aizenshtadt, Aleksandra, Lund, Kaja, Solberg, Nina, Lycke, Eric Maximilian, Thorvaldsen, Tor Espen, Espada, Sandra, Misaghian, Dorna, Page, Christian Magnus, Agafonov, Oleg, Nygård, Ståle, Chi, Nai-Wen, Lin, Eva, Tan, Jenille, Yu, Yihong, Costa, Mike, Krauss, Stefan, Waaler, Jo

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines von Mygland, Line, Mahmuda, Shoshy, Strand, Martin Frank, Olsen, Petter Angell, Aizenshtadt, Aleksandra, Lund, Kaja, Solberg, Nina, Lycke, Eric Maximilian, Thorvaldsen, Tor Espen, Espada, Sandra, Misaghian, Dorna, Page, Christian Magnus, Agafonov, Oleg, Nygård, Ståle, Chi, Nai-Wen, Lin, Eva, Tan, Jenille, Yu, Yihong, Costa, Mike, Krauss, Stefan, Waaler, Jo

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines von Mygland, Line, Mahmuda, Shoshy, Strand, Martin Frank, Olsen, Petter Angell, Aizenshtadt, Aleksandra, Lund, Kaja, Solberg, Nina, Lycke, Eric Maximilian, Thorvaldsen, Tor Espen, Espada, Sandra, Misaghian, Dorna, Page, Christian Magnus, Agafonov, Oleg, Nygård, Ståle, Chi, Nai-Wen, Lin, Eva, Tan, Jenille, Yu, Yihong, Costa, Mike, Krauss, Stefan, Waaler, Jo

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines von Mygland, Line, Mahmuda, Shoshy, Strand, Martin Frank, Olsen, Petter Angell, Aizenshtadt, Aleksandra, Lund, Kaja, Solberg, Nina, Lycke, Eric Maximilian, Thorvaldsen, Tor Espen, Espada, Sandra, Misaghian, Dorna, Page, Christian Magnus, Agafonov, Oleg, Nygård, Ståle, Chi, Nai-Wen, Lin, Eva, Tan, Jenille, Yu, Yihong, Costa, Mike, Krauss, Stefan, Waaler, Jo

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Additional file 9 of Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens von Jean-Philippe Fortin, Jenille Tan, Gascoigne, Karen E., Haverty, Peter M., Forrest, William F., Costa, Michael R., Martin, Scott E.

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Additional file 8 of Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens von Jean-Philippe Fortin, Jenille Tan, Gascoigne, Karen E., Haverty, Peter M., Forrest, William F., Costa, Michael R., Martin, Scott E.

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Additional file 4 of Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens von Jean-Philippe Fortin, Jenille Tan, Gascoigne, Karen E., Haverty, Peter M., Forrest, William F., Costa, Michael R., Martin, Scott E.

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