Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis von Tobe, Brian T. D., Crain, Andrew M., Winquist, Alicia M., Calabrese, Barbara, Makihara, Hiroko, Zhao, Wen-ning, Lalonde, Jasmin, Nakamura, Haruko, Konopaske, Glenn, Sidor, Michelle, Pernia, Cameron D., Yamashita, Naoya, Wada, Moyuka, Inoue, Yuuka, Nakamura, Fumio, Sheridan, Steven D., Logan, Ryan W., Brandel, Michael, Wu, Dongmei, Hunsberger, Joshua, Dorsett, Laurel, Duerr, Cordulla, Basa, Ranor C. B., McCarthy, Michael J., Udeshi, Namrata D., Mertins, Philipp, Carr, Steven A., Rouleau, Guy A., Mastrangelo, Lina, Li, Jianxue, Gutierrez, Gustavo J., Brill, Laurence M., Venizelos, Nikolaos, Chen, Guang, Nye, Jeffrey S., Manji, Husseini, Price, Jeffrey H., McClung, Colleen A., Akiskal, Hagop S., Alda, Martin, Chuang, De-Maw M., Coyle, Joseph T., Liu, Yang, Teng, Yang D., Ohshima, Toshio, Mikoshiba, Katsuhiko, Sidman, Richard L., Halpain, Shelley, Haggarty, Stephen J., Goshima, Yoshio, Snyder, Evan Y.

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Topiramate for Migraine Prevention in Adolescents: A Pooled Analysis of Efficacy and Safety von Winner, Paul, Gendolla, Astrid, Stayer, Catherine, Wang, Steven, Yuen, Eric, Battisti, Wendy P., Nye, Jeffrey S.

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Long-Term Open-Label Study of Adjunctive Topiramate in Infants With Refractory Partial-Onset Seizures von Puri, Vinay, Ness, Seth, Sattaluri, Sita Jayalakshmi, Wang, Steven, Todd, Mike, Yuen, Eric, Eerdekens, Marielle, Nye, Jeffrey S., Manitpisitkul, Prasarn, Shalayda, Kevin, Ford, Lisa

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Adaptive Behavior Outcomes in Infants Treated With Adjunctive Topiramate von Ness, Seth, MD, PhD, FAAP, Todd, Mike J., MS, Wang, Steven, PhD, Eerdekens, Marielle, MD, MBA, Nye, Jeffrey S., MD, PhD, Ford, Lisa, MD

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Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain von Gaiano, Nicholas, Nye, Jeffrey S., Fishell, Gord

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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells von Hitoshi, Seiji, Alexson, Tania, Tropepe, Vincent, Donoviel, Dorit, Elia, Andrew J, Nye, Jeffrey S, Conlon, Ronald A, Mak, Tak W, Bernstein, Alan, van der Kooy, Derek

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Intracellular Retention of Caveolin 1 in Presenilin-deficient Cells von Wood, Douglas R., Nye, Jeffrey S., Lamb, Ned J.C., Fernandez, Anne, Kitzmann, Magali

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Alzheimer's disease research and development: a call for a new research roadmap von Feldman, Howard H., Haas, Magali, Gandy, Sam, Schoepp, Darryle D., Cross, Alan J., Mayeux, Richard, Sperling, Reisa A., Fillit, Howard, van de Hoef, Diana L., Dougal, Sonya, Nye, Jeffrey S.

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Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer's disease von Hager, Klaus, Baseman, Alan S, Nye, Jeffrey S, Brashear, H Robert, Han, John, Sano, Mary, Davis, Bonnie, Richards, Henry M

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Identification and Characterization of Presenilin-independent Notch Signaling von Berechid, Bridget E., Kitzmann, Magali, Foltz, Daniel R., Roach, Arthur H., Seiffert, Dietmar, Thompson, Lorin A., Olson, Richard E., Bernstein, Alan, Donoviel, Dorit B., Nye, Jeffrey S.

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Effect of concomitant use of memantine on mortality and efficacy outcomes of galantamine-treated patients with Alzheimer's disease: post-hoc analysis of a randomized placebo-contro... von Hager, Klaus, Baseman, Alan S, Nye, Jeffrey S, Brashear, H Robert, Han, John, Sano, Mary, Davis, Bonnie, Richards, Henry M

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Pharmacokinetic–pharmacodynamic assessment of topiramate dosing regimens for children with epilepsy 2 to <10 years of age von Girgis, Ihab G., Nandy, Partha, Nye, Jeffrey S., Ford, Lisa, Mohanty, Surya, Wang, Steven, Ochalski, Stefan, Eerdekens, Marielle, Cox, Eugène

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Changes in gamma-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1 von Carter, Donald B, Dunn, Edwige, Pauley, Adele M, McKinley, Denise D, Fleck, Timothy J, Ellerbrook, Brenda R, Stratman, Nancy C, Zhou, Xiangdong, Himes, Carol S, Nye, Jeffrey S, Tomasselli, Alfredo, Yan, Riqiang

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Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells von Tobe, Brian TD, Snyder, Evan Y, Nye, Jeffrey S

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Evaluation of JNJ-26489112 in patients with photosensitive epilepsy: A placebo-controlled, exploratory study von Di Prospero, Nicholas A, Gambale, Jay J, Pandina, Gahan, Ford, Lisa, Girgis, Suzette, Moyer, John A, Xi, Liwen, Nye, Jeffrey S, Kasteleijn-Nolst Trenité, Dorothée

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The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized con... von Prins, Niels D, van der Flier, Wiesje A, Knol, Dirk L, Fox, Nick C, Brashear, H Robert, Nye, Jeffrey S, Barkhof, Frederik, Scheltens, Philip

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Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors von Chambers, C B, Peng, Y, Nguyen, H, Gaiano, N, Fishell, G, Nye, J S

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Signal Transduction by Activated mNotch: Importance of Proteolytic Processing and its Regulation by the Extracellular Domain von Kopan, Raphael, Schroeter, Eric H., Weintraub, Harold, Nye, Jeffrey S.

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The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD von KOPAN, R, NYE, J. S, WEINTRAUB, H

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Implications and limitations of cellular reprogramming for psychiatric drug development von Tobe, Brian T D, Brandel, Michael G, Nye, Jeffrey S, Snyder, Evan Y

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