Pathophysiology of Type 2 Diabetes Mellitus von Galicia-Garcia, Unai, Benito-Vicente, Asier, Jebari, Shifa, Larrea-Sebal, Asier, Siddiqi, Haziq, Uribe, Kepa B., Ostolaza, Helena, Martin, Cesar

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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles von Madsen, Thomas D., Hansen, Lasse H., Hintze, John, Ye, Zilu, Jebari, Shifa, Andersen, Daniel B., Joshi, Hiren J., Ju, Tongzhong, Goetze, Jens P., Martin, Cesar, Rosenkilde, Mette M., Holst, Jens J., Kuhre, Rune E., Goth, Christoffer K., Vakhrushev, Sergey Y., Schjoldager, Katrine T.

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Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease von Benito-Vicente, Asier, Uribe, Kepa B, Jebari, Shifa, Galicia-Garcia, Unai, Ostolaza, Helena, Martin, Cesar

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Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple‐Cell 2D Atherosclerosis Model von Jebari‐Benslaiman, Shifa, Uribe, Kepa B., Benito‐Vicente, Asier, Galicia‐Garcia, Unai, Larrea‐Sebal, Asier, Santin, Izortze, Alloza, Iraide, Vandenbroeck, Koen, Ostolaza, Helena, Martín, César

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Statin Treatment-Induced Development of Type 2 Diabetes: From Clinical Evidence to Mechanistic Insights von Galicia-Garcia, Unai, Jebari, Shifa, Larrea-Sebal, Asier, Uribe, Kepa B., Siddiqi, Haziq, Ostolaza, Helena, Benito-Vicente, Asier, Martin, Cesar

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Pathophysiology of Atherosclerosis von Jebari-Benslaiman, Shifa, Galicia-García, Unai, Larrea-Sebal, Asier, Olaetxea, Javier Rekondo, Alloza, Iraide, Vandenbroeck, Koen, Benito-Vicente, Asier, Martín, César

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Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants von Benito-Vicente, Asier, Uribe, Kepa B, Jebari, Shifa, Galicia-Garcia, Unai, Ostolaza, Helena, Martin, Cesar

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Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR von Galicia-Garcia, Unai, Benito-Vicente, Asier, Uribe, Kepa B., Jebari, Shifa, Larrea-Sebal, Asier, Alonso-Estrada, Rocio, Aguilo-Arce, Joseba, Ostolaza, Helena, Palacios, Lourdes, Martin, Cesar

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Cardiovascular Disease, Atherosclerosis and Familial Hypercholesterolemia: From Molecular Mechanisms Causing Pathogenicity to New Therapeutic Approaches von Jebari-Benslaiman, Shifa, Larrea-Sebal, Asier, Benito-Vicente, Asier, Martín, César

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OptiMo‐LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic Residues von Larrea‐Sebal, Asier, Sasiain, Iñaki, Jebari‐Benslaiman, Shifa, Galicia‐Garcia, Unai, Uribe, Kepa B., Benito‐Vicente, Asier, Gracia‐Rubio, Irene, Bediaga‐Bañeres, Harbil, Arrasate, Sonia, Cenarro, Ana, Civeira, Fernando, González‐Díaz, Humberto, Martín, Cesar

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Leu22_Leu23 Duplication at the Signal Peptide of PCSK9 Promotes Intracellular Degradation of LDLr and Autosomal Dominant Hypercholesterolemia von Benito-Vicente, Asier, Uribe, Kepa B., Larrea-Sebal, Asier, Palacios, Lourdes, Cenarro, Ana, Calle, Xabier, Galicia-Garcia, Unai, Jebari-Benslaiman, Shifa, Sánchez-Hernández, Rosa M., Stef, Marianne, Lambert, Gilles, Civeira, Fernando, Martín, Cesar

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Functional Characterization of p.(Arg160Gln) PCSK9 Variant Accidentally Found in a Hypercholesterolemic Subject von Larrea-Sebal, Asier, Trenti, Chiara, Jebari-Benslaiman, Shifa, Bertolini, Stefano, Calandra, Sebastiano, Negri, Emanuele A, Bonelli, Efrem, Benito-Vicente, Asier, Uraga-Gracianteparaluceta, Leire, Martín, César, Fasano, Tommaso

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miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression von Benito-Vicente, Asier, Uribe, Kepa B., Rotllan, Noemi, Ramirez, Cristina M., Jebari-Benslaiman, Shifa, Goedeke, Leigh, Canfran-Duque, Alberto, Galicia-Garcia, Unai, Saenz De Urturi, Diego, Aspichueta, Patricia, Suarez, Yajaira, Fernandez-Hernando, Carlos, Martin, Cesar

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Age, Origin and Functional Study of the Prevalent LDLR Mutation Causing Familial Hypercholesterolaemia in Gran Canaria von Suárez, Nicolás M, Jebari-Benslaiman, Shifa, Jiménez-Monzón, Roberto, Benito-Vicente, Asier, Brito-Casillas, Yeray, Garcés, Laida, González-Lleo, Ana M, Tugores, Antonio, Boronat, Mauro, Martin, César, Wägner, Ana M, Sánchez-Hernández, Rosa M

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Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells von Vado, Yerai, Puras, Gustavo, Rosique, Melania, Martin, Cesar, Pedraz, Jose Luis, Jebari-Benslaiman, Shifa, de Pancorbo, Marian M., Zarate, Jon, Perez de Nanclares, Guiomar

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Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition von Jebari-Benslaiman, Shifa, Uribe, Kepa B., Benito-Vicente, Asier, Galicia-Garcia, Unai, Larrea-Sebal, Asier, Alloza, Iraide, Vandenbroeck, Koen, Ostolaza, Helena, Martin, Cesar

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Leu22_Leu23 Duplication at the Signal Peptide of PCSK9 Promotes Intracellular Degradation of LDLr and Autosomal Dominant Hypercholesterolemia von Benito-Vicente, Asier, Uribe, Kepa B., Larrea-Sebal, Asier, Palacios, Lourdes, Cenarro, Ana, Calle, Xabier, Galicia-Garcia, Unai, Jebari, Shifa, Sánchez-Hernández, Rosa M., Stef, Marianne, Lambert, Gilles, Civeira, Fernando, Martín, Cesar

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The Arg499His gain-of-function mutation in the C-terminal domain of PCSK9 von Sánchez-Hernández, Rosa M., Di Taranto, Maria Donata, Benito-Vicente, Asier, Uribe, Kepa B., Lamiquiz-Moneo, Itziar, Larrea-Sebal, Asier, Jebari, Shifa, Galicia-Garcia, Unai, Nóvoa, F. Javier, Boronat, Mauro, Wägner, Ana M., Civeira, Fernando, Martín, César, Fortunato, Giuliana

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Functional characterization of LDL receptor missense variants located in the first cysteine-rich repeat in ligand binding domain of low density lipoprotein receptor von Siddiqi, Haziq, Benito, Asier, Jebari, Shifa, Etxebarria, Aitor, Uribe, Kepa, Galicia, Unai, Larrea, Asier, Palacios, Lourdes, Stef, Marianne, Ostalaza, Helena, Martin, Cesar

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Optimo-LDLr: An integrated in silico model with enhanced predictive power for LDL receptor variants, unraveling hot spot pathogenic residues von Larrea-Sebal, Asier, Sasiain, Iñaki, Jebari-Benslaiman, Shifa, Garcia, Unai Galicia, Uribe, Kepa Belloso, Benito-Vicente, Asier, Fernandez, Jorge, Gracia-Rubio, Irene, Arraste, Sonia, Lagunas, Ana Cenarro, Murillo, Fernando Civeira, Gonzalez-Diaz, Humberto, Martin, Cesar

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