Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass von Spinelli, Jessica B., Yoon, Haejin, Ringel, Alison E., Jeanfavre, Sarah, Clish, Clary B., Haigis, Marcia C.

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Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis von Brown, Eric M., Ke, Xiaobo, Hitchcock, Daniel, Jeanfavre, Sarah, Avila-Pacheco, Julian, Nakata, Toru, Arthur, Timothy D., Fornelos, Nadine, Heim, Cortney, Franzosa, Eric A., Watson, Nicki, Huttenhower, Curtis, Haiser, Henry J., Dillow, Glen, Graham, Daniel B., Finlay, B. Brett, Kostic, Aleksandar D., Porter, Jeffrey A., Vlamakis, Hera, Clish, Clary B., Xavier, Ramnik J.

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Identification of sequence changes in myosin II that adjust muscle contraction velocity von Johnson, Chloe A., McGreig, Jake E., Jeanfavre, Sarah T., Walklate, Jonathan, Vera, Carlos D., Farre, Marta, Mulvihill, Daniel P., Baines, Anthony J., Ridout, Martin, Leinwand, Leslie A., Wass, Mark N., Geeves, Michael A.

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REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors von Qiao, Shuxi, Koh, Siang-Boon, Vivekanandan, Varunika, Salunke, Devika, Patra, Krushna Chandra, Zaganjor, Elma, Ross, Kenneth, Mizukami, Yusuke, Jeanfavre, Sarah, Chen, Athena, Mino-Kenudson, Mari, Ramaswamy, Sridhar, Clish, Clary, Haigis, Marcia, Bardeesy, Nabeel, Ellisen, Leif W.

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Circulating amino acids and amino acid-related metabolites and risk of breast cancer among predominantly premenopausal women von Zeleznik, Oana A., Balasubramanian, Raji, Zhao, Yibai, Frueh, Lisa, Jeanfavre, Sarah, Avila-Pacheco, Julian, Clish, Clary B., Tworoger, Shelley S., Eliassen, A. Heather

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Intrapersonal Stability of Plasma Metabolomic Profiles over 10 Years among Women von Zeleznik, Oana A, Wittenbecher, Clemens, Deik, Amy, Jeanfavre, Sarah, Avila-Pacheco, Julian, Rosner, Bernard, Rexrode, Kathryn M, Clish, Clary B, Hu, Frank B, Eliassen, A Heather

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Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia von Mondal, Anupam K., Brock, Daniel C., Rowan, Sheldon, Yang, Zhi-Hong, Rojulpote, Krishna Vamsi, Smith, Kelsey M., Francisco, Sarah G., Bejarano, Eloy, English, Milton A., Deik, Amy, Jeanfavre, Sarah, Clish, Clary B., Remaley, Alan T., Taylor, Allen, Swaroop, Anand

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Human hematopoietic stem cell vulnerability to ferroptosis von Zhao, Jiawei, Jia, Yuemeng, Mahmut, Dilnar, Deik, Amy A., Jeanfavre, Sarah, Clish, Clary B., Sankaran, Vijay G.

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Size Specific Trapping at a Convergent Stagnation Point von Jeanfavre, Sarah, Pearce, Jennifer

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A Prospective Analysis of Circulating Plasma Metabolites Associated with Ovarian Cancer Risk von Zeleznik, Oana A., Eliassen, A. Heather, Kraft, Peter, Poole, Elizabeth M., Rosner, Bernard A., Jeanfavre, Sarah, Deik, Amy A., Bullock, Kevin, Hitchcock, Daniel S., Avila-Pacheco, Julian, Clish, Clary B., Tworoger, Shelley S.

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Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes von O'Sullivan, John F, Morningstar, Jordan E, Yang, Qiong, Zheng, Baohui, Gao, Yan, Jeanfavre, Sarah, Scott, Justin, Fernandez, Celine, Zheng, Hui, O'Connor, Sean, Cohen, Paul, Vasan, Ramachandran S, Long, Michelle T, Wilson, James G, Melander, Olle, Wang, Thomas J, Fox, Caroline, Peterson, Randall T, Clish, Clary B, Corey, Kathleen E, Gerszten, Robert E

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Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria von Li, Chenhao, Stražar, Martin, Mohamed, Ahmed M.T., Pacheco, Julian A., Walker, Rebecca L., Lebar, Tina, Zhao, Shijie, Lockart, Julia, Dame, Andrea, Thurimella, Kumar, Jeanfavre, Sarah, Brown, Eric M., Ang, Qi Yan, Berdy, Brittany, Sergio, Dallis, Invernizzi, Rachele, Tinoco, Antonio, Pishchany, Gleb, Vasan, Ramachandran S., Balskus, Emily, Huttenhower, Curtis, Vlamakis, Hera, Clish, Clary, Shaw, Stanley Y., Plichta, Damian R., Xavier, Ramnik J.

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Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course von Schirmer, Melanie, Stražar, Martin, Avila-Pacheco, Julian, Rojas-Tapias, Daniel F., Brown, Eric M., Temple, Emily, Deik, Amy, Bullock, Kevin, Jeanfavre, Sarah, Pierce, Kerry, Jin, Shen, Invernizzi, Rachele, Pust, Marie-Madlen, Costliow, Zach, Mack, David R., Griffiths, Anne M., Walters, Thomas, Boyle, Brendan M., Kugathasan, Subra, Vlamakis, Hera, Hyams, Jeffrey, Denson, Lee, Clish, Clary B., Xavier, Ramnik J.

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Effect of 1-year lifestyle intervention with energy-reduced Mediterranean diet and physical activity promotion on the gut metabolome and microbiota: a randomized clinical trial von García-Gavilán, Jesús F, Atzeni, Alessandro, Babio, Nancy, Liang, Liming, Belzer, Clara, Vioque, Jesús, Corella, Dolores, Fitó, Montserrat, Vidal, Josep, Moreno-Indias, Isabel, Torres-Collado, Laura, Coltell, Oscar, Toledo, Estefanía, Clish, Clary, Hernando, Javier, Yun, Huan, Hernández-Cacho, Adrián, Jeanfavre, Sarah, Dennis, Courtney, Gómez-Pérez, Ana M., Martínez, Maria Angeles, Ruiz-Canela, Miguel, Tinahones, Francisco J., Hu, Frank B., Salas-Salvadó, Jordi

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Vaginal Lactobacillus fatty acid response mechanisms reveal a metabolite-targeted strategy for bacterial vaginosis treatment von Zhu, Meilin, Frank, Matthew W., Radka, Christopher D., Jeanfavre, Sarah, Xu, Jiawu, Tse, Megan W., Pacheco, Julian Avila, Kim, Jae Sun, Pierce, Kerry, Deik, Amy, Hussain, Fatima Aysha, Elsherbini, Joseph, Hussain, Salina, Xulu, Nondumiso, Khan, Nasreen, Pillay, Vanessa, Mitchell, Caroline M., Dong, Krista L., Ndung'u, Thumbi, Clish, Clary B., Rock, Charles O., Blainey, Paul C., Bloom, Seth M., Kwon, Douglas S.

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Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis von Bjornevik, Kjetil, Zhang, Zhongli, OʼReilly, Éilis J, Berry, James D, Clish, Clary B, Deik, Amy, Jeanfavre, Sarah, Kato, Ikuko, Kelly, Rachel S, Kolonel, Laurence N, Liang, Liming, Marchand, Loic Le, McCullough, Marjorie L, Paganoni, Sabrina, Pierce, Kerry A, Schwarzschild, Michael A, Shadyab, Aladdin H, Wactawski-Wende, Jean, Wang, Dong D, Wang, Ying, Manson, JoAnn E, Ascherio, Alberto

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Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults von Chou, Chih‐Hung, Mohanty, Subhasis, Kang, Heather A., Kong, Lingjia, Avila‐Pacheco, Julian, Joshi, Samit R., Ueda, Ikuyo, Devine, Lesley, Raddassi, Khadir, Pierce, Kerry, Jeanfavre, Sarah, Bullock, Kevin, Meng, Hailong, Clish, Clary, Santori, Fabio R., Shaw, Albert C., Xavier, Ramnik J.

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Prediagnostic plasma branched-chain amino acids and the risk of amyotrophic lateral sclerosis von Bjornevik, Kjetil, OʼReilly, Éilis J, Berry, James D, Clish, Clary B, Jeanfavre, Sarah, Kato, Ikuko, Kolonel, Laurence N, Le Marchand, Loic, McCullough, Marjorie L, Paganoni, Sabrina, Schwarzschild, Michael A, Talbott, Evelyn O, Wallace, Robert B, Zhang, Zhongli, Manson, JoAnn E, Ascherio, Alberto

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Branched-Chain Amino Acids and Risk of Breast Cancer von Zeleznik, Oana A, Balasubramanian, Raji, Ren, Yumeng, Tobias, Deirdre K, Rosner, Bernard A, Peng, Cheng, Bever, Alaina M, Frueh, Lisa, Jeanfavre, Sarah, Avila-Pacheco, Julian, Clish, Clary B, Mora, Samia, Hu, Frank B, Eliassen, A Heather

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Abstract 13814: DMGV is a Novel Marker of Liver Fat and Predicts Future Development of Type 2 Diabetes von O’Sullivan, John F, Morningstar, Jordan E, Zheng, Baohui, Jeanfavre, Sarah, Scott, Justin, Yang, Qiong, Fernandez, Celine, Vasan, Rakmachandran S, Long, Michelle T, Melander, Olle, Wang, Thomas J, Fox, Caroline, Peterson, Randall T, Clish, Clary, Corey, Kathleen, Gerszten, Robert E

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