A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia von Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.

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Analysis of the androgen receptor–regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression von Zhang, Yajia, Pitchiaya, Sethuramasundaram, Cieślik, Marcin, Niknafs, Yashar S., Tien, Jean C.-Y., Hosono, Yasuyuki, Iyer, Matthew K., Yazdani, Sahr, Subramaniam, Shruthi, Shukla, Sudhanshu K., Jiang, Xia, Wang, Lisha, Liu, Tzu-Ying, Uhl, Michael, Gawronski, Alexander R., Qiao, Yuanyuan, Xiao, Lanbo, Dhanasekaran, Saravana M., Juckette, Kristin M., Kunju, Lakshmi P., Cao, Xuhong, Patel, Utsav, Batish, Mona, Shukla, Girish C., Paulsen, Michelle T., Ljungman, Mats, Jiang, Hui, Mehra, Rohit, Backofen, Rolf, Sahinalp, Cenk S., Freier, Susan M., Watt, Andrew T., Guo, Shuling, Wei, John T., Feng, Felix Y., Malik, Rohit, Chinnaiyan, Arul M.

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Tracing the origins of relapse in acute myeloid leukaemia to stem cells von Shlush, Liran I., Mitchell, Amanda, Heisler, Lawrence, Abelson, Sagi, Ng, Stanley W. K., Trotman-Grant, Aaron, Medeiros, Jessie J. F., Rao-Bhatia, Abilasha, Jaciw-Zurakowsky, Ivana, Marke, Rene, McLeod, Jessica L., Doedens, Monica, Bader, Gary, Voisin, Veronique, Xu, ChangJiang, McPherson, John D., Hudson, Thomas J., Wang, Jean C. Y., Minden, Mark D., Dick, John E.

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A 17-gene stemness score for rapid determination of risk in acute leukaemia von Ng, Stanley W. K., Mitchell, Amanda, Kennedy, James A., Chen, Weihsu C., McLeod, Jessica, Ibrahimova, Narmin, Arruda, Andrea, Popescu, Andreea, Gupta, Vikas, Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., Bullinger, Lars, Herold, Tobias, Görlich, Dennis, Büchner, Thomas, Hiddemann, Wolfgang, Berdel, Wolfgang E., Wörmann, Bernhard, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Metzeler, Klaus, Buske, Christian, Löwenberg, Bob, Valk, Peter J. M., Zandstra, Peter W., Minden, Mark D., Dick, John E., Wang, Jean C. Y.

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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia von Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin, Zelent, Arthur

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Perspective of Positron Annihilation Spectroscopy in Polymers von Jean, Y. C., Van Horn, J. David, Hung, Wei-Song, Lee, Kuier-Rarn

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Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia von Škrtić, Marko, Sriskanthadevan, Shrivani, Jhas, Bozhena, Gebbia, Marinella, Wang, Xiaoming, Wang, Zezhou, Hurren, Rose, Jitkova, Yulia, Gronda, Marcela, Maclean, Neil, Lai, Courteney K., Eberhard, Yanina, Bartoszko, Justyna, Spagnuolo, Paul, Rutledge, Angela C., Datti, Alessandro, Ketela, Troy, Moffat, Jason, Robinson, Brian H., Cameron, Jessie H., Wrana, Jeffery, Eaves, Connie J., Minden, Mark D., Wang, Jean C.Y., Dick, John E., Humphries, Keith, Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.

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CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells von Surka, Christine, Jin, Liqing, Mbong, Nathan, Lu, Chin-Chun, Jang, In Sock, Rychak, Emily, Mendy, Derek, Clayton, Thomas, Tindall, Elizabeth, Hsu, Christy, Fontanillo, Celia, Tran, Eileen, Contreras, Adrian, Ng, Stanley W.K., Matyskiela, Mary, Wang, Kai, Chamberlain, Philip, Cathers, Brian, Carmichael, James, Hansen, Joshua, Wang, Jean C.Y., Minden, Mark D., Fan, Jinhong, Pierce, Daniel W., Pourdehnad, Michael, Rolfe, Mark, Lopez-Girona, Antonia, Dick, John E., Lu, Gang

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Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells von Notta, Faiyaz, Mullighan, Charles G., Wang, Jean C. Y., Poeppl, Armando, Doulatov, Sergei, Phillips, Letha A., Ma, Jing, Minden, Mark D., Downing, James R., Dick, John E.

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NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis von LI QIN, WU, Ye-Lin, ZHIHUI YANG, YAN XU, THEISSEN, Sarah M, YI LI, YOUNG, Leonie, JIANMING XU, TONEFF, Michael J, DABING LI, LAN LIAO, XIUHUA GAO, BANE, Fiona T, TIEN, Jean C.-Y, YIXIANG XU, ZHEN FENG

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Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties von Boutzen, Héléna, Murison, Alex, Oriecuia, Alexa, Bansal, Suraj, Arlidge, Christopher, Wang, Jean C. Y., Lupien, Mathieu, Kaufmann, Kerstin B., Dick, John E.

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TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding von Petrova, Penka S, Viller, Natasja Nielsen, Wong, Mark, Pang, Xinli, Lin, Gloria H Y, Dodge, Karen, Chai, Vien, Chen, Hui, Lee, Vivian, House, Violetta, Vigo, Noel T, Jin, Debbie, Mutukura, Tapfuma, Charbonneau, Marilyse, Truong, Tran, Viau, Stephane, Johnson, Lisa D, Linderoth, Emma, Sievers, Eric L, Maleki Vareki, Saman, Figueredo, Rene, Pampillo, Macarena, Koropatnick, James, Trudel, Suzanne, Mbong, Nathan, Jin, Liqing, Wang, Jean C Y, Uger, Robert A

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Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study von Castelo-Branco, Pedro, PhD, Choufani, Sanaa, PhD, Mack, Stephen, BSc, Gallagher, Denis, PhD, Zhang, Cindy, MSc, Lipman, Tatiana, MSc, Zhukova, Nataliya, MD, Walker, Erin J, PhD, Martin, Dianna, PhD, Merino, Diana, MSc, Wasserman, Jonathan D, MD, Elizabeth, Cynthia, MSc, Alon, Noa, BSc, Zhang, Libo, PhD, Hovestadt, Volker, MSc, Kool, Marcel, PhD, Jones, David TW, PhD, Zadeh, Gelareh, MD, Croul, Sidney, Prof, Hawkins, Cynthia, MD, Hitzler, Johann, MD, Wang, Jean CY, MD, Baruchel, Sylvain, Prof, Dirks, Peter B, Prof, Malkin, David, Prof, Pfister, Stefan, MD, Taylor, Michael D, MD, Weksberg, Rosanna, Prof, Tabori, Uri, Dr

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Myelodysplastic syndromes: the complexity of stem-cell diseases von Corey, Seth J., Minden, Mark D., Barber, Dwayne L., Kantarjian, Hagop, Wang, Jean C. Y., Schimmer, Aaron D.

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Mapping the cellular origin and early evolution of leukemia in Down syndrome von Wagenblast, Elvin, Araújo, Joana, Gan, Olga I, Cutting, Sarah K, Murison, Alex, Krivdova, Gabriela, Azkanaz, Maria, McLeod, Jessica L, Smith, Sabrina A, Gratton, Blaise A, Marhon, Sajid A, Gabra, Martino, Medeiros, Jessie J F, Manteghi, Sanaz, Chen, Jian, Chan-Seng-Yue, Michelle, Garcia-Prat, Laura, Salmena, Leonardo, De Carvalho, Daniel D, Abelson, Sagi, Abdelhaleem, Mohamed, Chong, Karen, Roifman, Maian, Shannon, Patrick, Wang, Jean C Y, Hitzler, Johann K, Chitayat, David, Dick, John E, Lechman, Eric R

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Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells von Takenaka, Katsuto, Prasolava, Tatiana K, Wang, Jean C Y, Mortin-Toth, Steven M, Khalouei, Sam, Gan, Olga I, Dick, John E, Danska, Jayne S

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Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia von Cole, Alicia, Wang, Zezhou, Coyaud, Etienne, Voisin, Veronique, Gronda, Marcela, Jitkova, Yulia, Mattson, Rachel, Hurren, Rose, Babovic, Sonja, Maclean, Neil, Restall, Ian, Wang, Xiaoming, Jeyaraju, Danny V., Sukhai, Mahadeo A., Prabha, Swayam, Bashir, Shaheena, Ramakrishnan, Ashwin, Leung, Elisa, Qia, Yi Hua, Zhang, Nianxian, Combes, Kevin R., Ketela, Troy, Lin, Fengshu, Houry, Walid A., Aman, Ahmed, Al-awar, Rima, Zheng, Wei, Wienholds, Erno, Xu, Chang Jiang, Dick, John, Wang, Jean C.Y., Moffat, Jason, Minden, Mark D., Eaves, Connie J., Bader, Gary D., Hao, Zhenyue, Kornblau, Steven M., Raught, Brian, Schimmer, Aaron D.

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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells von Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.

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Molecular design of the cellulose ester-based forward osmosis membranes for desalination von Zhang, Sui, Wang, Kai Yu, Chung, Tai-Shung, Jean, Y.C., Chen, Hongmin

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A survey study of the psychological impact of COVID-19 pandemic on physician parents von Lo, Jean C. Y., Walters, E. Lea, Bengiamin, Deena I., Spivey, Emma M., Wegrzyn, Katelyyn C., Reibling, Ellen

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