MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration von Lee, Eunju, Hwang, Inhwa, Park, Sangjun, Hong, Sujeong, Hwang, Boreum, Cho, Yoeseph, Son, Junghyun, Yu, Je-Wook

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SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease von Kim, So Ra, Lee, Sang-Guk, Kim, Soo Hyun, Kim, Jin Hee, Choi, Eunhye, Cho, Wonhee, Rim, John Hoon, Hwang, Inhwa, Lee, Chan Joo, Lee, Minyoung, Oh, Chang-Myung, Jeon, Justin Y., Gee, Heon Yung, Kim, Jeong-Ho, Lee, Byung-Wan, Kang, Eun Seok, Cha, Bong-Soo, Lee, Myung-Shik, Yu, Je-Wook, Cho, Jin Won, Kim, Jung-Sun, Lee, Yong-ho

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Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance von Yu, Je-Wook, Lee, Myung-Shik

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA von Fernandes-Alnemri, Teresa, Yu, Je-Wook, Datta, Pinaki, Wu, Jianghong, Alnemri, Emad S.

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Distinct Features of Brain-Resident Macrophages: Microglia and Non-Parenchymal Brain Macrophages von Lee, Eunju, Eo, Jun-Cheol, Lee, Changjun, Yu, Je-Wook

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Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation von Won, Ji-Hee, Park, Sangjun, Hong, Sujeong, Son, Seunghwan, Yu, Je-Wook

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PGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis von Nam, Bo Young, Jhee, Jong Hyun, Park, Jimin, Kim, Seonghun, Kim, Gyuri, Park, Jung Tak, Yoo, Tae-Hyun, Kang, Shin-Wook, Yu, Je-Wook, Han, Seung Hyeok

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Defective mitochondrial fission augments NLRP3 inflammasome activation von Park, Sangjun, Won, Ji-Hee, Hwang, Inhwa, Hong, Sujeong, Lee, Heung Kyu, Yu, Je-Wook

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SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models von Kwon, Oh‐Chan, Song, Jae‐Jin, Yang, Yunseon, Kim, Seong‐Hoon, Kim, Ji Young, Seok, Min‐Jong, Hwang, Inhwa, Yu, Je‐Wook, Karmacharya, Jenisha, Maeng, Han‐Joo, Kim, Jiyoung, Jho, Eek‐hoon, Ko, Seung Yeon, Son, Hyeon, Chang, Mi‐Yoon, Lee, Sang‐Hun

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Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome von Juliana, Christine, Fernandes-Alnemri, Teresa, Wu, Jianghong, Datta, Pinaki, Solorzano, Leobaldo, Yu, Je-Wook, Meng, Rong, Quong, Andrew A., Latz, Eicke, Scott, Charles P., Alnemri, Emad S.

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Advanced glycation end products impair NLRP3 inflammasome–mediated innate immune responses in macrophages von Son, Seunghwan, Hwang, Inhwa, Han, Seung Hyeok, Shin, Jeon-Soo, Shin, Ok Sarah, Yu, Je-Wook

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The AIM2 inflammasome is critical for innate immunity to Francisella tularensis von Fernandes-Alnemri, Teresa, Datta, Pinaki, Huang, Lan, Juliana, Christine, Eisenlohr, Laurence, Yu, Je-Wook, Landel, Carlisle P, Alnemri, Emad S, Kang, Seokwon, Solorzano, Leobaldo, McCormick, Margaret, Wu, Jianghong, McDermott, Erin

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25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome von Jang, Jiho, Park, Sangjun, Jin Hur, Hye, Cho, Hyun-Ju, Hwang, Inhwa, Pyo Kang, Yun, Im, Isak, Lee, Hyunji, Lee, Eunju, Yang, Wonsuk, Kang, Hoon-Chul, Won Kwon, Sung, Yu, Je-Wook, Kim, Dong-Wook

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Histone deacetylase 6 negatively regulates NLRP3 inflammasome activation von Hwang, Inhwa, Lee, Eunju, Jeon, Seon-A, Yu, Je-Wook

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Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling von Yang, Jungmin, Hwang, Inhwa, Lee, Eunju, Shin, Sung Jae, Lee, Eun-Jin, Rhee, Joon Haeng, Yu, Je-Wook

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Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa von Oh, Ji Eun, Kim, Byoung-Chan, Chang, Dong-Ho, Kwon, Meehyang, Lee, Sun Young, Kang, Dukjin, Kim, Jin Young, Hwang, Inhwa, Yu, Je-Wook, Nakae, Susumu, Lee, Heung Kyu

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Neutrophils Facilitate Prolonged Inflammasome Response in the DAMP-Rich Inflammatory Milieu von Son, Seunghwan, Yoon, Sung-Hyun, Chae, Byeong Jun, Hwang, Inhwa, Shim, Do-Wan, Choe, Young Ho, Hyun, Young-Min, Yu, Je-Wook

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Varicella zoster virus glycoprotein E facilitates PINK1/Parkin-mediated mitophagy to evade STING and MAVS-mediated antiviral innate immunity von Oh, Soo-Jin, Yu, Je-Wook, Ahn, Jin-Hyun, Choi, Seok Tae, Park, Hosun, Yun, Jeanho, Shin, Ok Sarah

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Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation von Son, Seunghwan, Shim, Do-Wan, Hwang, Inhwa, Park, Jong-Hwan, Yu, Je-Wook

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Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis von Shim, Do-Wan, Eo, Jun-Cheol, Kim, Saeyoung, Hwang, Inhwa, Nam, BoYoung, Shin, Jae-Eun, Han, Seung Hyeok, Yu, Je-Wook

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