The ubiquitin-proteasome pathway and proteasome inhibitors von Myung, Jayhyuk, Kim, Kyung Bo, Crews, Craig M.

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Lack of Proteasome Active Site Allostery as Revealed by Subunit-Specific Inhibitors von Myung, Jayhyuk, Kim, Kyung Bo, Lindsten, Kristina, Dantuma, Nico P, Crews, Craig M

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856 - INTERIM DATA FROM THE FIRST-IN-HUMAN PHASE 1/2A TRIAL OF ICM-203, AN INTRA-ARTICULAR, AAV GENE THERAPY FOR OSTEOARTHRITIS - SAFETY, TOLERABILITY, AND PRELIMINARY EVALUATION O... von Heald, Alison E., Solomon, Lucien B., Page, Richard, Ahn, Yoenhee, Yum, Young Na, Myung, Jayhyuk, Collins, Jamie E., Guermazi, Ali, Kim, Dae-Won

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INTERIM DATA FROM THE FIRST-IN-HUMAN PHASE 1/2A TRIAL OF ICM-203, AN INTRA-ARTICULAR, AAV GENE THERAPY FOR OSTEOARTHRITIS - SAFETY, TOLERABILITY, AND PRELIMINARY EVALUATION OF CLIN... von Heald, Alison E., Solomon, Lucien B., Page, Richard, Ahn, Yoenhee, Yum, Young Na, Myung, Jayhyuk, Collins, Jamie E., Guermazi, Ali, Kim, Dae-Won

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Cells Adapted to the Proteasome Inhibitor 4-Hydroxy-5-Iodo-3-Nitrophenylacetyl-Leu-Leu-Leucinal-Vinyl Sulfone Require Enzymatically Active Proteasomes for Continued Survival von Princiotta, Michael F., Schubert, Ulrich, Chen, Weisan, Bennink, Jack R., Myung, Jayhyuk, Crew, Craig M., Yewdell, Jonathan W.

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Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: Insights into specificity and potency von Kim, Kyung Bo, Myung, Jayhyuk, Sin, Ny, Crews, Craig M.

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Abstract 6044: BR101801: A potent and selective inhibitor of DNA-PK, potentiates the activity of topoisomerase II inhibitor in vitro and causes tumor inhibition in cancer models von Son, Mi Kwon, Wang, Seungho, Lee, Bo Ram, Jeon, Byeongwook, Kim, Soo jung, Yang, Enhui, Park, Min, Lee, Joo han, Myung, Jayhyuk

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Abstract 655: BR101801: A first-in-class triple-inhibitor of PI3K gamma/delta and DNA-PK targeting non-Hodgkin's lymphoma von Lee, Bo Ram, Wang, Seungho, Son, Mi kwon, Jeon, Byeongwook, Kim, Soo Jung, Yang, Eunhui, Park, Min, Lee, Joo Han, Myung, Jayhyuk

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Abstract 4439: BR101801 triggers anti-tumor immunity and enhances efficacy of immune checkpoint antibodies in syngeneic model von Wang, Seungho, Son, Mi kwon, Lee, Bo Ram, Jeon, Byeongwook, Kim, Soo Jung, Yang, Eunhui, Park, Min, Lee, Joo Han, Myung, Jayhyuk

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Abstract 871: BR101801: A first-in-class dual inhibitor of PI3Kδ and DNA-PK in non-Hodgkin's lymphoma von Son, Mi Kwon, Jeon, Byeongwook, Wang, Jin Sang, Kim, Baek kyung, Lee, Bo Ram, Choi, Yeon seo, Kim, Nam-Hoon, Myung, Jayhyuk, Kim, Dal-Hyun

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Abstract 1939: BR101801, a first-in-class dual target inhibitor of DNA protein kinase (DNA-PK) and phosphoinositide 3-kinase delta (PI3Kδ), triggers antitumor immunity von Jeon, Byeongwook, Wang, Jin Sang, Kim, Baek kyung, Lee, Bo Ram, Son, Mi kwon, Choi, Yeon seo, Kim, Nam-Hoon, Myung, Jayhyuk, Kim, Dal-Hyun

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Combination of BR101801 and Venetoclax Demonstrates Synergistic Activity in DLBCL Cell Lines Harboring Double Hit and Double Expressor Alterations von Jung, Hahn-Sun, Kim, Nam Hoon, Wang, Jinsang, Son, Mi Kwon, Kim, Baek-Kyung, Jeon, Byeongwook, Choi, Yeonseo, Myung, Jayhyuk, Kim, Dal-Hyun

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Discovery of BR102375, a new class of non-TZD PPARγ full agonist for the treatment of type 2 diabetes von Choung, Wonken, Yang, Deokmo, Kim, Hakdo, Choi, Hyukjoon, Lee, Bo Ram, Park, Min, Jang, Su Min, Lim, Jae Soo, Kim, Woo Sik, Kim, Kyung-Hee, Chin, Jungwook, Jung, Kyungjin, Lee, Geumwoo, Hong, Eunmi, Jang, Tae-ho, Joo, Jeongmin, Hwang, Hayoung, Myung, Jayhyuk, Kim, Seong Heon

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Identification of BR101549 as a lead candidate of non-TZD PPARγ agonist for the treatment of type 2 diabetes: Proof-of-concept evaluation and SAR von Choung, Wonken, Jung, Hui Jin, Yang, Deokmo, Nam, Eun Hye, Choi, Hyukjoon, Lee, Bo Ram, Park, Min, Jang, Su Min, Lim, Jae Soo, Kim, Woo Sik, Kim, Kyung-Hee, Chin, Jungwook, Jung, Kyungjin, Lee, Geumwoo, Hong, Eunmi, Jang, Tae-ho, Myung, Jayhyuk, Kim, Seong Heon

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Population Pharmacokinetic Modeling of the Enterohepatic Recirculation of Fimasartan in Rats, Dogs, and Humans von Kim, Tae Hwan, Shin, Soyoung, Landersdorfer, Cornelia B., Chi, Yong Ha, Paik, Soo Heui, Myung, Jayhyuk, Yadav, Rajbharan, Horkovics-Kovats, Stefan, Bulitta, Jürgen B., Shin, Beom Soo

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Monoclonal antibodies against autocrine motility factor suppress gastric cancer von Jung, Hahn-Sun, Lee, Su In, Kang, Seung-Hoon, Wang, Jin Sang, Yang, Eun Hee, Jeon, Byungwook, Myung, Jayhyuk, Baek, Ji Young, Park, Song-Kyu

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Calcium ATPase of sarcoplasmic reticulum has four binding sites for calcium von Jencks, William P, Yang, Tong, Peisach, Daniel, Myung, Jayhyuk

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High-Throughput Screening by Mass Spectrometry: Comparison with the Scintillation Proximity Assay with a Focused-File Screen of AKT1/PKBα von Quercia, Andrea K., Lamarr, William A., Myung, Jayhyuk, Özbal, Can C., Landro, James A., Lumb, Kevin J.

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Corrigendum to “A high-throughput competitive scintillation proximity aminoacyl–tRNA synthetase charging assay to measure amino acid concentration” [Anal. Biochem. 363 (2007) 246–2... von Forbes, Chris D., Myung, Jayhyuk, Szewczak, Alexander A., Landro, James A.

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A high-throughput competitive scintillation proximity aminoacyl–tRNA synthetase charging assay to measure amino acid concentration von Forbes, Chris D., Myung, Jayhyuk, Landro, James A.

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