In search of a new paradigm for protective immunity to TB von Nunes-Alves, Cláudio, Booty, Matthew G., Carpenter, Stephen M., Jayaraman, Pushpa, Rothchild, Alissa C., Behar, Samuel M.

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TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts von Grauel, Angelo L., Nguyen, Beverly, Ruddy, David, Laszewski, Tyler, Schwartz, Stephanie, Chang, Jonathan, Chen, Julie, Piquet, Michelle, Pelletier, Marc, Yan, Zheng, Kirkpatrick, Nathaniel D., Wu, Jincheng, deWeck, Antoine, Riester, Markus, Hims, Matt, Geyer, Felipe Correa, Wagner, Joel, MacIsaac, Kenzie, Deeds, James, Diwanji, Rohan, Jayaraman, Pushpa, Yu, Yenyen, Simmons, Quincey, Weng, Shaobu, Raza, Alina, Minie, Brian, Dostalek, Mirek, Chikkegowda, Pavitra, Ruda, Vera, Iartchouk, Oleg, Chen, Naiyan, Thierry, Raphael, Zhou, Joseph, Pruteanu-Malinici, Iulian, Fabre, Claire, Engelman, Jeffrey A., Dranoff, Glenn, Cremasco, Viviana

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Emerging Tim-3 functions in antimicrobial and tumor immunity von Sakuishi, Kaori, Jayaraman, Pushpa, Behar, Samuel M, Anderson, Ana C, Kuchroo, Vijay K

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TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection von Jayaraman, Pushpa, Jacques, Miye K, Zhu, Chen, Steblenko, Katherine M, Stowell, Britni L, Madi, Asaf, Anderson, Ana C, Kuchroo, Vijay K, Behar, Samuel M

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iNKT cell production of GM-CSF controls Mycobacterium tuberculosis von Rothchild, Alissa C., Jayaraman, Pushpa, Alves, Cláudio, Behar, Samuel M.

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Tim3 binding to galectin-9 stimulates antimicrobial immunity von Jayaraman, Pushpa, Sada-Ovalle, Isabel, Beladi, Sarah, Anderson, Ana C, Dardalhon, Valerie, Hotta, Chie, Kuchroo, Vijay K, Behar, Samuel M

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Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques von Ng, Cherie T, Jaworski, J Pablo, Jayaraman, Pushpa, Sutton, William F, Delio, Patrick, Kuller, LaRene, Anderson, David, Landucci, Gary, Richardson, Barbra A, Burton, Dennis R, Forthal, Donald N, Haigwood, Nancy L

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IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection von Booty, Matthew G., Barreira-Silva, Palmira, Carpenter, Stephen M., Nunes-Alves, Cláudio, Jacques, Miye K., Stowell, Britni L., Jayaraman, Pushpa, Beamer, Gillian, Behar, Samuel M.

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Continuous Viral Escape and Selection by Autologous Neutralizing Antibodies in Drug-Naïve Human Immunodeficiency Virus Controllers von MAHALANABIS, Madhumita, JAYARAMAN, Pushpa, MIURA, Toshiyuki, PEREYRA, Florencia, CHESTER, E. Michael, RICHARDSON, Barbra, WALKER, Bruce, HAIGWOOD, Nancy L

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1438 Stromal hypersialylation within colorectal tumors contributes to immunosuppression of T cell adaptive immunity in the tumor microenvironment von Treacy, Oliver, Che, Jenny, Gatlin, Wayne, Cao, Lizhi, Egan, Hannah, O’Neill, Aoise, O’Dwyer, Michael, Jayaraman, Pushpa, Peng, Li, Ryan, Aideen E

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Requirement for Invariant Chain in Macrophages for Mycobacterium tuberculosis Replication and CD1d Antigen Presentation von Sillé, Fenna C M, Martin, Constance, Jayaraman, Pushpa, Rothchild, Alissa, Fortune, Sarah, Besra, Gurdyal S, Behar, Samuel M, Boes, Marianne

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Evidence for Persistent, Occult Infection in Neonatal Macaques following Perinatal Transmission of Simian-Human Immunodeficiency Virus SF162P3 von JAYARAMAN, Pushpa, TUOFU ZHU, HAIGWOOD, Nancy L, MISHER, Lynda, MOHAN, Deepika, KULLER, Larene, POLACINO, Patricia, RICHARDSON, Barbra A, BIELEFELDT-OHMANN, Helle, ANDERSON, David, HU, Shiu-Lok

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IL-1β promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation von Jayaraman, Pushpa, Sada-Ovalle, Isabel, Nishimura, Tomoyasu, Anderson, Ana C, Kuchroo, Vijay K, Remold, Heinz G, Behar, Samuel M

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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment von Egan, Hannah, Treacy, Oliver, Lynch, Kevin, Leonard, Niamh A., O’Malley, Grace, Reidy, Eileen, O’Neill, Aoise, Corry, Shania M., De Veirman, Kim, Vanderkerken, Karin, Egan, Laurence J., Ritter, Thomas, Hogan, Aisling M., Redmond, Keara, Peng, Li, Che, Jenny, Gatlin, Wayne, Jayaraman, Pushpa, Sheehan, Margaret, Canney, Aoife, Hynes, Sean O., Kerr, Emma M., Dunne, Philip D., O’Dwyer, Michael E., Ryan, Aideen E.

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SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms von Wang, Ye, Mohseni, Morvarid, Grauel, Angelo, Diez, Javier Estrada, Guan, Wei, Liang, Simon, Choi, Jiyoung Elizabeth, Pu, Minying, Chen, Dongshu, Laszewski, Tyler, Schwartz, Stephanie, Gu, Jane, Mansur, Leandra, Burks, Tyler, Brodeur, Lauren, Velazquez, Roberto, Kovats, Steve, Pant, Bhavesh, Buruzula, Giri, Deng, Emily, Chen, Julie T., Sari-Sarraf, Farid, Dornelas, Christina, Varadarajan, Malini, Yu, Haiyan, Liu, Chen, Lim, Joanne, Hao, Huai-Xiang, Jiang, Xiaomo, Malamas, Anthony, LaMarche, Matthew J., Geyer, Felipe Correa, McLaughlin, Margaret, Costa, Carlotta, Wagner, Joel, Ruddy, David, Jayaraman, Pushpa, Kirkpatrick, Nathaniel D., Zhang, Pu, Iartchouk, Oleg, Aardalen, Kimberly, Cremasco, Viviana, Dranoff, Glenn, Engelman, Jeffrey A., Silver, Serena, Wang, Hongyun, Hastings, William D., Goldoni, Silvia

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Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: Immunity interruptus von Behar, Samuel M, Carpenter, Stephen M, Booty, Matthew G, Barber, Daniel L, Jayaraman, Pushpa

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Abstract 5640: Targeting tumor-promoting inflammation (TPI) via the IL-1βpathway for cancer immunotherapy von Jayaraman, Pushpa, Rodrik-Outmezguine, Vanessa, Millholland, John, O'Brien, Neil, Wong, Connie, Diwanji, Rohan, Wang, Muchun, Choi, Elizabeth, Linnartz, Ronald, Rose, Kristine, Pelletier, Marc, Savchenko, Alexander, Luo, Tong, Rezek, Valerie, Kitchen, Scott, Baum, Jason, Sabatos-Peyton, Catherine, Martin, Anne-Marie, Dranoff, Glenn

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Multiple Inflammatory Cytokines Converge To Regulate CD8+ T Cell Expansion and Function during Tuberculosis von Booty, Matthew G, Nunes-Alves, Cláudio, Carpenter, Stephen M, Jayaraman, Pushpa, Behar, Samuel M

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The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis von Sada-Ovalle, Isabel, Chávez-Galán, Leslie, Torre-Bouscoulet, Luis, Nava-Gamiño, Lourdes, Barrera, Lourdes, Jayaraman, Pushpa, Torres-Rojas, Martha, Salazar-Lezama, Miguel Angel, Behar, Samuel M

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Defining the contribution of T cell exhaustion to failed immunity during TB von Jacques, Miye K, Jayaraman, Pushpa, Kuchroo, Vijay K, Behar, Samuel M

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