The IMpact of PerioperAtive KeTamine on Enhanced Recovery after Abdominal Surgery (IMPAKT ERAS): protocol for a pragmatic, randomized, double-blinded, placebo-controlled trial von Raymond, Britany L, Allen, Brian F S, Freundlich, Robert E, Parrish, Crystal G, Jayaram, Jennifer E, Wanderer, Jonathan P, Rice, Todd W, Lindsell, Christopher J, Scharfman, Kevin H, Dear, Mary L, Gao, Yue, Hiser, William D, McEvoy, Matthew D

Volltext

Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10 von Maeder, Morgan L., Stefanidakis, Michael, Wilson, Christopher J., Baral, Reshica, Barrera, Luis Alberto, Bounoutas, George S., Bumcrot, David, Chao, Hoson, Ciulla, Dawn M., DaSilva, Jennifer A., Dass, Abhishek, Dhanapal, Vidya, Fennell, Tim J., Friedland, Ari E., Giannoukos, Georgia, Gloskowski, Sebastian W., Glucksmann, Alexandra, Gotta, Gregory M., Jayaram, Hariharan, Haskett, Scott J., Hopkins, Bei, Horng, Joy E., Joshi, Shivangi, Marco, Eugenio, Mepani, Rina, Reyon, Deepak, Ta, Terence, Tabbaa, Diana G., Samuelsson, Steven J., Shen, Shen, Skor, Maxwell N., Stetkiewicz, Pam, Wang, Tongyao, Yudkoff, Clifford, Myer, Vic E., Albright, Charles F., Jiang, Haiyan

Volltext

Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials von Albrecht, Brian K, Gehling, Victor S, Hewitt, Michael C, Vaswani, Rishi G, Côté, Alexandre, Leblanc, Yves, Nasveschuk, Christopher G, Bellon, Steve, Bergeron, Louise, Campbell, Robert, Cantone, Nico, Cooper, Michael R, Cummings, Richard T, Jayaram, Hariharan, Joshi, Shivangi, Mertz, Jennifer A, Neiss, Adrianne, Normant, Emmanuel, O’Meara, Michael, Pardo, Eneida, Poy, Florence, Sandy, Peter, Supko, Jeffrey, Sims, Robert J, Harmange, Jean-Christophe, Taylor, Alexander M, Audia, James E

Volltext

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Opioid Minimization in Opioid-Naïve Patients von Wu, Christopher L., King, Adam B., Geiger, Timothy M., Grant, Michael C., Grocott, Michael P. W., Gupta, Ruchir, Hah, Jennifer M., Miller, Timothy E., Shaw, Andrew D., Gan, Tong J., Thacker, Julie K. M., Mythen, Michael G., McEvoy, Matthew D.

Volltext

American Society for Enhanced Recovery and Perioperative Quality Initiative-4 Joint Consensus Statement on Persistent Postoperative Opioid Use: Definition, Incidence, Risk Factors,... von Kent, Michael L., Hurley, Robert W., Oderda, Gary M., Gordon, Debra B., Sun, Eric, Mythen, Monty, Miller, Timothy E., Shaw, Andrew D., Gan, Tong J., Thacker, Julie K. M., McEvoy, Matthew D.

Volltext

Data transparency and demographic representation in approval packages of FDA-approved oncology drugs from 2012-2021 von Liu, Jingyi, Jayaram, Gowri, Varma, Tanvee, Sammut, Stephen, Guerra, Carmen, Miller, Jennifer E.

Volltext

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Management of Patients on Preoperative Opioid Therapy von Edwards, David A., Hedrick, Traci L., Jayaram, Jennifer, Argoff, Charles, Gulur, Padma, Holubar, Stefan D., Gan, Tong J., Mythen, Michael G., Miller, Timothy E., Shaw, Andrew D., Thacker, Julie K. M., McEvoy, Matthew D.

Volltext

Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990–2019: results from the Global Burden of Disease Study 2019 von Ma, Jianing, Novotney, Amanda, Biehl, Molly H, Ross, Jennifer M, Adnani, Qorinah Estiningtyas Sakilah, Ahmad, Sajjad Ahmad, Alipour, Vahid, Alvis-Guzman, Nelson, Amini, Saeed, Androudi, Sofia, Arabloo, Jalal, Arja, Asrat, Asemahagn, Mulusew A, Atre, Sachin R, Babar, Zaheer-Ud-Din, Baig, Atif Amin, Barrow, Amadou, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bijani, Ali, Briko, Nikolay Ivanovich, Carvalho, Felix, Chatterjee, Souranshu, Christopher, Devasahayam J, Dagnew, Amare Belachew, Dai, Xiaochen, Dhamnetiya, Deepak, Dianatinasab, Mostafa, Emami, Amir, Farzadfar, Farshad, Fernandes, Eduarda, Ferro Desideri, Lorenzo, Fischer, Florian, Frank, Tahvi D, Garcia-Basteiro, Alberto L, Ghadiri, Keyghobad, Goodridge, Amador, Gupta, Bhawna, Gupta, Vivek Kumar, Haider, Mohammad Rifat, Hamidi, Samer, Haque, Shafiul, Harapan, Harapan, Hassan, Shoaib, Hayat, Khezar, Househ, Mowafa, Irvani, Seyed Sina Naghibi, Itumalla, Ramaiah, Jayaram, Shubha, Joukar, Farahnaz, Kanchan, Tanuj, Kandel, Himal, Kim, Yun Jin, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Koyanagi, Ai, Lak, Hassan Mehmood, Lin, Christine, Madhava Kunjathur, Shilpashree, Madi, Deepak, Memish, Ziad A, Mendoza, Walter, Mesregah, Mohamed Kamal, Misra, Sanjeev, Moghadaszadeh, Masoud, Moni, Mohammad Ali, Montasir, Ahmed Al, Nair, Suma, Naqvi, Atta Abbas, Nayak, Biswa Prakash, Neupane Kandel, Sandhya, Nguyen, Trang Huyen, P A, Mahesh, Pashazadeh Kan, Fatemeh, Pirestani, Majid, Postma, Maarten J, Prashant, Akila, Pribadi, Dimas Ria Angga, Rafiei, Alireza, Rawaf, David Laith, Rezaei, Nima, Rezapour, Aziz, Samadi Kafil, Hossein, Samy, Abdallah M, Seylani, Allen, Shafaat, Omid, Silva, João Pedro, Thapar, Rekha, Tleyjeh, Imad I, Vo, Bay, Walters, Magdalene K, Yiğit, Vahit, Yu, Chuanhua, Yunusa, Ismaeel, Zastrozhina, Anasthasia, Zhang, Zhi-Jiang, Zumla, Alimuddin, Salomon, Joshua A, Vos, Theo, Murray, Christopher J L

Volltext

Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors von Gehling, Victor S, Hewitt, Michael C, Vaswani, Rishi G, Leblanc, Yves, Côté, Alexandre, Nasveschuk, Christopher G, Taylor, Alexander M, Harmange, Jean-Christophe, Audia, James E, Pardo, Eneida, Joshi, Shivangi, Sandy, Peter, Mertz, Jennifer A, Sims, Robert J, Bergeron, Louise, Bryant, Barbara M, Bellon, Steve, Poy, Florence, Jayaram, Hariharan, Sankaranarayanan, Ravichandran, Yellapantula, Sreegouri, Bangalore Srinivasamurthy, Nandana, Birudukota, Swarnakumari, Albrecht, Brian K

Volltext

Taste dysfunction in multiple sclerosis von Doty, Richard L., Tourbier, Isabelle A., Pham, Dzung L., Cuzzocreo, Jennifer L., Udupa, Jayaram K., Karacali, Bilge, Beals, Evan, Fabius, Laura, Leon-Sarmiento, Fidias E., Moonis, Gul, Kim, Taehoon, Mihama, Toru, Geckle, Rena J., Yousem, David M.

Volltext

Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition von Ghosh, Srimoyee, Taylor, Alexander, Chin, Melissa, Huang, Hon-Ren, Conery, Andrew R., Mertz, Jennifer A., Salmeron, Andres, Dakle, Pranal J., Mele, Deanna, Cote, Alexandre, Jayaram, Hari, Setser, Jeremy W., Poy, Florence, Hatzivassiliou, Georgia, DeAlmeida-Nagata, Denise, Sandy, Peter, Hatton, Charlie, Romero, F. Anthony, Chiang, Eugene, Reimer, Thornik, Crawford, Terry, Pardo, Eneida, Watson, Venita G., Tsui, Vickie, Cochran, Andrea G., Zawadzke, Laura, Harmange, Jean-Christophe, Audia, James E., Bryant, Barbara M., Cummings, Richard T., Magnuson, Steven R., Grogan, Jane L., Bellon, Steve F., Albrecht, Brian K., Sims, Robert J., Lora, Jose M.

Volltext

Expanding CRISPR Genome Editing Strategies in Hematopoietic Stem and Progenitor Cells for the Treatment of Hematologic Diseases von deDreuzy, Edouard, Chalishazar, Aditi, Heath, Jack, Margulies, Carrie M, Labella, John, Viswanathan, Ramya, Loveluck, Katherine, Chang, KaiHsin, Jayaram, Hariharan, Zuris, John A, Myer, Vic E, Albright, Charlie, Cotta-Ramusino, Cecilia, Gori, Jennifer L

Volltext

Development of methyl isoxazoleazepines as inhibitors of BET von Hewitt, Michael C, Leblanc, Yves, Gehling, Victor S, Vaswani, Rishi G, Côté, Alexandre, Nasveschuk, Christopher G, Taylor, Alexander M, Harmange, Jean-Christophe, Audia, James E, Pardo, Eneida, Cummings, Rich, Joshi, Shivangi, Sandy, Peter, Mertz, Jennifer A, Sims, 3rd, Robert J, Bergeron, Louise, Bryant, Barbara M, Bellon, Steve, Poy, Florence, Jayaram, Hariharan, Jayaran, Hariharan, Tang, Yong, Albrecht, Brian K

Volltext

Discovery of Benzotriazolo[4,3‑d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains von Taylor, Alexander M, Vaswani, Rishi G, Gehling, Victor S, Hewitt, Michael C, Leblanc, Yves, Audia, James E, Bellon, Steve, Cummings, Richard T, Côté, Alexandre, Harmange, Jean-Christophe, Jayaram, Hari, Joshi, Shivangi, Lora, Jose M, Mertz, Jennifer A, Neiss, Adrianne, Pardo, Eneida, Nasveschuk, Christopher G, Poy, Florence, Sandy, Peter, Setser, Jeremy W, Sims, Robert J, Tang, Yong, Albrecht, Brian K

Volltext

Corrigendum to “Development of methyl isoxazoleazepines as inhibitors of BET” [Bioorg. Med. Chem. Lett. 25/9 (2015) 1842–1848] von Hewitt, Michael C., Leblanc, Yves, Gehling, Victor S., Vaswani, Rishi G., Côté, Alexandre, Nasveschuk, Christopher G., Taylor, Alexander M., Harmange, Jean-Christophe, Audia, James E., Pardo, Eneida, Cummings, Rich, Joshi, Shivangi, Sandy, Peter, Mertz, Jennifer A., Sims, Robert J., Bergeron, Louise, Bryant, Barbara M., Bellon, Steve, Poy, Florence, Jayaram, Hariharan, Tang, Yong, Albrecht, Brian K.

Volltext

Scaling down an insect-size microrobot, HAMR-VI into HAMR-Jr von Jayaram, Kaushik, Shum, Jennifer, Castellanos, Samantha, Helbling, E. Farrell, Wood, Robert J

Volltext bestellen

Synthesis and structure-activity relationships of M2-selective muscarinic receptor ligands in the 1-[4-(4-arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family von MCCOMBIE, Stuart W, LIN, Sue-Ing, RUPERTO, Vilma B, DUFFY, Ruth A, LACHOWICZ, Jean E, TAGAT, Jayaram R, NAZARENO, Dennis, VICE, Susan, FORD, Jennifer, ASBEROM, Theodros, LEONE, Daria, KOZLOWSKI, Joseph A, GUOWEI ZHOU

Volltext

Scaling down an insect-size microrobot, HAMR-VI into HAMR-Jr von Jayaram, Kaushik, Shum, Jennifer, Castellanos, Samantha, E Farrell Helbling, Wood, Robert J

Volltext

Synthesis and structure-activity relationships of M(2)-selective muscarinic receptor ligands in the 1-[4-(4-arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family von McCombie, Stuart W, Lin, Sue Ing, Tagat, Jayaram R, Nazareno, Dennis, Vice, Susan, Ford, Jennifer, Asberom, Theodros, Leone, Daria, Kozlowski, Joseph A, Zhou, Guowei, Ruperto, Vilma B, Duffy, Ruth A, Lachowicz, Jean E

Volltext

Synthesis and structure–Activity relationships of M 2-Selective muscarinic receptor ligands in the 1-[4-(4-Arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family von McCombie, Stuart W, Lin, Sue-Ing, Tagat, Jayaram R, Nazareno, Dennis, Vice, Susan, Ford, Jennifer, Asberom, Theodros, Leone, Daria, Kozlowski, Joseph A, Zhou, Guowei, Ruperto, Vilma B, Duffy, Ruth A, Lachowicz, Jean E

Volltext