Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease von Forner, Stefania, Kawauchi, Shimako, Balderrama-Gutierrez, Gabriela, Kramár, Enikö A., Matheos, Dina P., Phan, Jimmy, Javonillo, Dominic I., Tran, Kristine M., Hingco, Edna, da Cunha, Celia, Rezaie, Narges, Alcantara, Joshua A., Baglietto-Vargas, David, Jansen, Camden, Neumann, Jonathan, Wood, Marcelo A., MacGregor, Grant R., Mortazavi, Ali, Tenner, Andrea J., LaFerla, Frank M., Green, Kim N.

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Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology von Baglietto-Vargas, David, Forner, Stefania, Cai, Lena, Martini, Alessandra C., Trujillo-Estrada, Laura, Swarup, Vivek, Nguyen, Marie Minh Thu, Do Huynh, Kelly, Javonillo, Dominic I., Tran, Kristine Minh, Phan, Jimmy, Jiang, Shan, Kramár, Enikö A., Nuñez-Diaz, Cristina, Balderrama-Gutierrez, Gabriela, Garcia, Franklin, Childs, Jessica, Rodriguez-Ortiz, Carlos J., Garcia-Leon, Juan Antonio, Kitazawa, Masashi, Shahnawaz, Mohammad, Matheos, Dina P., Ma, Xinyi, Da Cunha, Celia, Walls, Ken C., Ager, Rahasson R., Soto, Claudio, Gutierrez, Antonia, Moreno-Gonzalez, Ines, Mortazavi, Ali, Tenner, Andrea J., MacGregor, Grant R., Wood, Marcelo, Green, Kim N., LaFerla, Frank M.

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Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease von Javonillo, Dominic I, Tran, Kristine M, Phan, Jimmy, Hingco, Edna, Kramár, Enikö A, da Cunha, Celia, Forner, Stefania, Kawauchi, Shimako, Milinkeviciute, Giedre, Gomez-Arboledas, Angela, Neumann, Jonathan, Banh, Crystal E, Huynh, Michelle, Matheos, Dina P, Rezaie, Narges, Alcantara, Joshua A, Mortazavi, Ali, Wood, Marcelo A, Tenner, Andrea J, MacGregor, Grant R, Green, Kim N, LaFerla, Frank M

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A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques von Tran, Kristine M, Kawauchi, Shimako, Kramár, Enikö A, Rezaie, Narges, Liang, Heidi Yahan, Sakr, Jasmine S, Gomez-Arboledas, Angela, Arreola, Miguel A, Cunha, Celia da, Phan, Jimmy, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai-Xuan, Neumann, Jonathan, Filimban, Ghassan, Shi, Zechuan, Milinkeviciute, Giedre, Javonillo, Dominic I, Tran, Katelynn, Gantuz, Magdalena, Forner, Stefania, Swarup, Vivek, Tenner, Andrea J, LaFerla, Frank M, Wood, Marcelo A, Mortazavi, Ali, MacGregor, Grant R, Green, Kim N

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BIN1 K358R variant in 5xFAD mice ameliorates AB pathology and microgliosis von Tran, Katelynn, Milinkeviciute, Giedre, Tran, Kristine M, Phan, Jimmy, Da Cunha, Celia, Javonillo, Dominic I, Kawauchi, Shimako, Tenner, Andrea J, LaFerla, Frank, MacGregor, Grant R, Green, Kim N

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Late‐onset AD risk mutation PICALM H458R prevents plaque generation in 5xFAD mice von Gomez‐Arboledas, Angela, Tran, Kristine M, Javonillo, Dominic I, Phan, Jimmy, Milinkeviciute, Giedre, Da Cunha, Celia, Forner, Stefania, Kawauchi, Shimako, Tenner, Andrea J, LaFerla, Frank, MacGregor, Grant R, Green, Kim N

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The Clu‐rs2279590_h2kb variant increases axonal and neuritic damage in 5xFAD mice von Milinkeviciute, Giedre, Tran, Katelynn, Tran, Kristine M, Phan, Jimmy, Da Cunha, Celia, Javonillo, Dominic I, Neumann, Jonathan, Alcantara, Joshua A, Walker, Amber, Kawauchi, Shimako, Tenner, Andrea J, LaFerla, Frank, MacGregor, Grant R, Green, Kim N

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ABCA7V1599M variant in 5xFAD mice mediates differences in amyloid‐beta pathology and reactive gliosis von Butler, Claire Ann, Javonillo, Dominic I, Houchin, Lauren A, Kawauchi, Shimako, Phan, Jimmy, Da Cunha, Celia, Tran, Katelynn, Milinkeviciute, Giedre, Tenner, Andrea J, LaFerla, Frank, MacGregor, Grant R, Green, Kim N

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Late‐onset AD risk mutation PICALMH458R prevents plaque generation in 5xFAD mice von Gomez‐Arboledas, Angela, Tran, Kristine M, Javonillo, Dominic I, Phan, Jimmy, Milinkeviciute, Giedre, Da Cunha, Celia, Forner, Stefania, Kawauchi, Shimako, Tenner, Andrea J, LaFerla, Frank, MacGregor, Grant R, Green, Kim N

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Trem2 R47H NSS; 5xFAD mice display age/disease progression‐dependent changes in plaques and plaque‐associated microglia, and increased plasma neurofilament light chain von Tran, Kristine M, Kawauchi, Shimako, Javonillo, Dominic I, Da Cunha, Celia, Phan, Jimmy, Rezaie, Narges, Liang, Heidi Yahan, Milinkeviciute, Giedre, Gomez‐Arboledas, Angela, Forner, Stefania, Mortazavi, Ali, Tenner, Andrea J, LaFerla, Frank, MacGregor, Grant R, Green, Kim N

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Accumulation of periodic‐acid Schiff granules is increased in the presence of humanized amyloid beta von Forner, Stefania, Javonillo, Dominic I, Tran, Kristine M, Phan, Jimmy, Da Cunha, Celia, Baglietto‐Vargas, David, Kawauchi, Shimako, Tenner, Andrea J, LaFerla, Frank, MacGregor, Grant R, Green, Kim N

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A Trem2 R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques von Tran, Kristine M, Kawauchi, Shimako, Kramár, Enikö A, Rezaie, Narges, Liang, Heidi Yahan, Sakr, Jasmine S, Gomez-Arboledas, Angela, Arreola, Miguel A, Cunha, Celia da, Phan, Jimmy, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai-Xuan, Neumann, Jonathan, Filimban, Ghassan, Shi, Zechuan, Milinkeviciute, Giedre, Javonillo, Dominic I, Tran, Katelynn, Gantuz, Magdalena, Forner, Stefania, Swarup, Vivek, Tenner, Andrea J, LaFerla, Frank M, Wood, Marcelo A, Mortazavi, Ali, MacGregor, Grant R, Green, Kim N

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A Trem2 R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques von Kristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine S. Sakr, Angela Gomez-Arboledas, Miguel A. Arreola, Celia da Cunha, Jimmy Phan, Shuling Wang, Sherilyn Collins, Amber Walker, Kai-Xuan Shi, Jonathan Neumann, Ghassan Filimban, Zechuan Shi, Giedre Milinkeviciute, Dominic I. Javonillo, Katelynn Tran, Magdalena Gantuz, Stefania Forner, Vivek Swarup, Andrea J. Tenner, Frank M. LaFerla, Marcelo A. Wood, Ali Mortazavi, Grant R. MacGregor, Kim N. Green

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Additional file 1 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques von Tran, Kristine M., Kawauchi, Shimako, Kramár, Enikö A., Rezaie, Narges, Liang, Heidi Yahan, Sakr, Jasmine S., Gomez-Arboledas, Angela, Arreola, Miguel A., Cunha, Celia da, Phan, Jimmy, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai-Xuan, Neumann, Jonathan, Filimban, Ghassan, Shi, Zechuan, Milinkeviciute, Giedre, Javonillo, Dominic I., Tran, Katelynn, Gantuz, Magdalena, Forner, Stefania, Swarup, Vivek, Tenner, Andrea J., LaFerla, Frank M., Wood, Marcelo A., Mortazavi, Ali, MacGregor, Grant R., Green, Kim N.

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SPG302 Reverses Synaptic and Cognitive Deficits Without Altering Amyloid or Tau Pathology in a Transgenic Model of Alzheimer’s Disease von Trujillo-Estrada, Laura, Vanderklish, Peter W., Nguyen, Marie Minh Thu, Kuang, Run Rong, Nguyen, Caroline, Huynh, Eric, da Cunha, Celia, Javonillo, Dominic Ibarra, Forner, Stefania, Martini, Alessandra C., Sarraf, Stella T., Simmon, Vincent F., Baglietto-Vargas, David, LaFerla, Frank M.

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Ablation of microglia following infection of the central nervous system with a neurotropic murine coronavirus infection leads to increased demyelination and impaired remyelination von Cheng, Yuting, Javonillo, Dominic Ibarra, Pachow, Collin, Scarfone, Vanessa M., Fernandez, Kellie, Walsh, Craig M., Green, Kim N., Lane, Thomas E.

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Amyloid-beta impairs TOM1-mediated IL-1R1 signaling von Martini, Alessandra Cadete, Gomez-Arboledas, Angela, Forner, Stefania, Rodriguez-Ortiz, Carlos J., McQuade, Amanda, Danhash, Emma, Phan, Jimmy, Javonillo, Dominic, Ha, Jordan-Vu, Tram, Melanie, Trujillo-Estrada, Laura, da Cunha, Celia, Ager, Rahasson R., Davila, Jose C., Kitazawa, Masashi, Blurton-Jones, Mathew, Gutierrez, Antonia, Baglietto-Vargas, David, Medeiros, Rodrigo, LaFerla, Frank M.

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The Abca7 V1613M variant reduces Aβ generation, plaque load, and neuronal damage von Butler, Claire A, Mendoza Arvilla, Adrian, Milinkeviciute, Giedre, Da Cunha, Celia, Kawauchi, Shimako, Rezaie, Narges, Liang, Heidi Y, Javonillo, Dominic, Thach, Annie, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai-Xuan, Neumann, Jonathan, Gomez-Arboledas, Angela, Henningfield, Caden M, Hohsfield, Lindsay A, Mapstone, Mark, Tenner, Andrea J, LaFerla, Frank M, Mortazavi, Ali, MacGregor, Grant R, Green, Kim N

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The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage von Butler, Claire A., Mendoza Arvilla, Adrian, Milinkeviciute, Giedre, Da Cunha, Celia, Kawauchi, Shimako, Rezaie, Narges, Liang, Heidi Y., Javonillo, Dominic, Thach, Annie, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai‐Xuan, Neumann, Jonathan, Gomez‐Arboledas, Angela, Henningfield, Caden M., Hohsfield, Lindsay A., Mapstone, Mark, Tenner, Andrea J., LaFerla, Frank M., Mortazavi, Ali, MacGregor, Grant R., Green, Kim N.

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Genetic diversity promotes resilience in a mouse model of Alzheimer's disease von Soni, Neelakshi, Hohsfield, Lindsay A., Tran, Kristine M., Kawauchi, Shimako, Walker, Amber, Javonillo, Dominic, Phan, Jimmy, Matheos, Dina, Da Cunha, Celia, Uyar, Asli, Milinkeviciute, Giedre, Gomez‐Arboledas, Angela, Tran, Katelynn, Kaczorowski, Catherine C., Wood, Marcelo A., Tenner, Andrea J., LaFerla, Frank M., Carter, Gregory W., Mortazavi, Ali, Swarup, Vivek, MacGregor, Grant R., Green, Kim N.

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