Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators von Kruegel, Andrew C, Gassaway, Madalee M, Kapoor, Abhijeet, Váradi, András, Majumdar, Susruta, Filizola, Marta, Javitch, Jonathan A, Sames, Dalibor

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Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors von Sykes, David A., Moore, Holly, Stott, Lisa, Holliday, Nicholas, Javitch, Jonathan A., Lane, J. Robert, Charlton, Steven J.

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Single-molecule analysis of ligand efficacy in β2AR–G-protein activation von Gregorio, G. Glenn, Masureel, Matthieu, Hilger, Daniel, Terry, Daniel S., Juette, Manuel, Zhao, Hong, Zhou, Zhou, Perez-Aguilar, Jose Manuel, Hauge, Maria, Mathiasen, Signe, Javitch, Jonathan A., Weinstein, Harel, Kobilka, Brian K., Blanchard, Scott C.

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Roles of the Akt/GSK-3 and Wnt Signaling Pathways in Schizophrenia and Antipsychotic Drug Action von Freyberg, Zachary, Ferrando, Stephen J, Javitch, Jonathan A

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The role of kinetic context in apparent biased agonism at GPCRs von Klein Herenbrink, Carmen, Sykes, David A., Donthamsetti, Prashant, Canals, Meritxell, Coudrat, Thomas, Shonberg, Jeremy, Scammells, Peter J., Capuano, Ben, Sexton, Patrick M., Charlton, Steven J., Javitch, Jonathan A., Christopoulos, Arthur, Lane, J. Robert

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CrossTalk opposing view: Weighing the evidence for class A GPCR dimers, the jury is still out von Lambert, Nevin A., Javitch, Jonathan A.

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Potentiating SLC transporter activity: Emerging drug discovery opportunities von Rives, Marie-Laure, Javitch, Jonathan A., Wickenden, Alan D.

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The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na + and Substrate Is Triggered by Substrate in a Second Binding Site von Shi, Lei, Quick, Matthias, Zhao, Yongfang, Weinstein, Harel, Javitch, Jonathan A.

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Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum von Gallo, Eduardo F., Meszaros, Jozsef, Sherman, Jeremy D., Chohan, Muhammad O., Teboul, Eric, Choi, Claire S., Moore, Holly, Javitch, Jonathan A., Kellendonk, Christoph

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What can crystal structures of aminergic receptors tell us about designing subtype-selective ligands? von Michino, Mayako, Beuming, Thijs, Donthamsetti, Prashant, Newman, Amy Hauck, Javitch, Jonathan A, Shi, Lei

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Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation von Javitch, Jonathan A, Han, Yang, Moreira, Irina S, Urizar, Eneko, Weinstein, Harel

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Elucidating the molecular logic of a metabotropic glutamate receptor heterodimer von Lin, Xin, Provasi, Davide, Niswender, Colleen M., Asher, Wesley B., Javitch, Jonathan A.

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Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor von Donthamsetti, Prashant C, Broichhagen, Johannes, Vyklicky, Vojtech, Stanley, Cherise, Fu, Zhu, Visel, Meike, Levitz, Joshua L, Javitch, Jonathan A, Trauner, Dirk, Isacoff, Ehud Y

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Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain von Serafini, Randal A, Estill, Molly, Pekarskaya, Elizabeth A, Sakloth, Farhana, Shen, Li, Javitch, Jonathan A, Zachariou, Venetia

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Single-molecule dynamics of gating in a neurotransmitter transporter homologue von Blanchard, Scott C, Javitch, Jonathan A, Zhao, Yongfang, Terry, Daniel, Shi, Lei, Weinstein, Harel

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The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter von Shan, Jufang, Javitch, Jonathan A, Shi, Lei, Weinstein, Harel

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Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist von Donthamsetti, Prashant C, Winter, Nils, Schönberger, Matthias, Levitz, Joshua, Stanley, Cherise, Javitch, Jonathan A, Isacoff, Ehud Y, Trauner, Dirk

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Dopamine D2 receptors form higher order oligomers at physiological expression levels von Guo, Wen, Urizar, Eneko, Kralikova, Michaela, Mobarec, Juan Carlos, Shi, Lei, Filizola, Marta, Javitch, Jonathan A

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Monitoring the function of membrane transport proteins in detergent-solubilized form von Quick, Matthias, Javitch, Jonathan A

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Conformational dynamics of ligand-dependent alternating access in LeuT von Kazmier, Kelli, Sharma, Shruti, Quick, Matthias, Islam, Shahidul M, Roux, Benoît, Weinstein, Harel, Javitch, Jonathan A, Mchaourab, Hassane S

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