Myeloma CAR-T CRS Management With IL-1R Antagonist Anakinra von Jatiani, Shashidhar S., Aleman, Adolfo, Madduri, Deepu, Chari, Ajai, Cho, Hearn Jay, Richard, Shambavi, Richter, Joshua, Brody, Joshua, Jagannath, Sundar, Parekh, Samir

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SOX11 augments BCR signaling to drive MCL-like tumor development von Kuo, Pei-Yu, Jatiani, Shashidhar S., Rahman, Adeeb H., Edwards, Donna, Jiang, Zewei, Ahr, Katya, Perumal, Deepak, Leshchenko, Violetta V., Brody, Joshua, Shaknovich, Rita, Ye, B. Hilda, Parekh, Samir

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SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma von Jatiani, Shashidhar S., Christie, Stephanie, Leshchenko, Violetta V., Jain, Rinku, Kapoor, Abhijeet, Bisignano, Paola, Lee, Clement, Kaniskan, H. Umit, Edwards, Donna, Meng, Fanye, Lagana, Alessandro, Youssef, Youssef, Wiestner, Adrian, Alinari, Lapo, Jin, Jian, Filizola, Marta, Aggarwal, Aneel K., Parekh, Samir

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Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies von Jatiani, Shashidhar S, Baker, Stacey J, Silverman, Lewis R, Reddy, E Premkumar

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Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2) von Reddy, M.V. Ramana, Akula, Balireddy, Jatiani, Shashidhar, Vasquez-Del Carpio, Rodrigo, Billa, Vinay K., Mallireddigari, Muralidhar R., Cosenza, Stephen C., Venkata Subbaiah, D.R.C., Bharathi, E. Vijaya, Pallela, Venkat R., Ramkumar, Poornima, Jain, Rinku, Aggarwal, Aneel K., Reddy, E. Premkumar

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Design, synthesis and evaluation of ( E)-α-benzylthio chalcones as novel inhibitors of BCR-ABL kinase von Reddy, M.V. Ramana, Pallela, Venkat R., Cosenza, Stephen C., Mallireddigari, Muralidhar R., Patti, Revathi, Bonagura, Marie, Truongcao, May, Akula, Balaiah, Jatiani, Shashidhar S., Reddy, E. Premkumar

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Dynamin Interacts with Members of the Sumoylation Machinery von Mishra, Ram Kumar, Jatiani, Shashidhar S, Kumar, Ashutosh, Simhadri, Venkateswara Rao, Hosur, Ramakrishna V, Mittal, Rohit

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A Non-ATP-Competitive Dual Inhibitor of JAK2 and BCR-ABL Kinases: Elucidation of a Novel Therapeutic Spectrum Based on Substrate Competitive Inhibition von Jatiani, Shashidhar S, Cosenza, Stephen C, Reddy, M V Ramana, Ha, Ji Hee, Baker, Stacey J, Samanta, Ajoy K, Olnes, Matthew J, Pfannes, Loretta, Sloand, Elaine M, Arlinghaus, Ralph B, Reddy, E Premkumar

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Expression of the antiviral protein MxA in cells transiently perturbs endocytosis von Jatiani, Shashidhar S., Mittal, Rohit

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Aberrant Cell Cycle Programming Confers Rapid Lethality in the EuSOX11+ CCND1 MCL Mouse Model von Edwards, Donna R, Kuo, Pei-yu, Lagana, Alessandro, Park, Seongjee, Nedumaran, Pavithra, Leshchenko, Violetta, Christie, Stephanie, Jatiani, Shashidhar, Teruya-Feldstein, Julie, Parekh, Samir

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SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma von Jatiani, Shashidhar S., Christie, Stephanie, Leshchenko, Violetta V., Jain, Rinku, Kapoor, Abhijeet, Bisignano, Paola, Lee, Clement, Kaniskan, H. uemit, Edwards, Donna, Meng, Fanye, Lagana, Alessandro, Youssef, Youssef, Wiestner, Adrian, Alinari, Lapo, Jin, Jian, Filizola, Marta, Aggarwal, Aneel K., Parekh, Samir

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SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma von Jatiani, Shashidhar S., Christie, Stephanie, Leshchenko, Violetta V., Jain, Rinku, Kapoor, Abhijeet, Bisignano, Paola, Lee, Clement, Kaniskan, H. Umit, Edwards, Donna, Meng, Fanye, Lagana, Alessandro, Youssef, Youssef, Wiestner, Adrian, Alinari, Lapo, Jin, Jian, Filizola, Marta, Aggarwal, Aneel K., Parekh, Samir

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Inhibiting SOX11-DNA Interaction in Mantle Cell Lymphoma von Christie, Stephanie, Jatiani, Shashidhar, Kuo, Pei-Yu, Leshchenko, Violetta, Kapoor, Abhijeet, Bisignano, Paola, Aggarwal, Aneel, Filizola, Marta, Parekh, Samir

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Conformational analysis of the GTP-binding protein MxA using limited proteolysis von Varne, Anjali, Muthukumaraswamy, Karthika, Jatiani, Shashidhar S, Mittal, Rohit

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Abstract 2450: Identifying novel substrates of PLK2 using a chemical genetics approach von Ramkumar, Poornima, Levin, Rebecca S., Sansó, Miriam, Jatiani, Shashidhar, Dar, Arvin C., Fisher, Robert P., Shokat, Kevan M., Reddy, E Premkumar

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Abstract 4537: Pharmacokinetics of PLK2 inhibitor GBO-006-1, developed as a novel first-in-class molecule to treat triple negative breast cancer von ROYCHOWDHURY, ARNAB, DURAISWAMY, ATHISAYAMANI JEYARAJ, MADDI, SRINIVASARAO, DEB, CHANDRA, MITRA, SAYAN, REDDY, RAMANA, MANIAR, MANOJ, JATIANI, SHASHIDHAR, COSENZA, STEPHEN C., PADGAONKAR, AMOL, REDDY, PREMKUMAR

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Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyri d o[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2) von Reddy, MVRamana, Akula, Balireddy, Jatiani, Shashidhar, Carpio, Rodrigo Vasquez-Del, Billa, Vinay K, Mallireddigari, Muralidhar R, Cosenza, Stephen C, Subbaiah, DRCVenkata, Bharathi, EVijaya, Pallela, Venkat R, Ramkumar, Poornima, Jain, Rinku, Aggarwal, Aneel K, Reddy, EPremkumar

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Abstract 643: Targeting cancer with a selective ATP-mimetic inhibitor of polo like kinase-2 von Jatiani, Shashidhar S., Cosenza, Stephen C., Billa, Vinay K., Reddy, M.V. Ramana, Reddy, E Premkumar

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A Non-ATP-Competitive Dual Inhibitor of JAK2V617F and BCR-ABLT315I Kinases: Elucidation of a Novel Therapeutic Spectrum Based on Substrate Competitive Inhibition von Jatiani, S. S., Cosenza, S. C., Reddy, M. V. R., Ha, J. H., Baker, S. J., Samanta, A. K., Olnes, M. J., Pfannes, L., Sloand, E. M., Arlinghaus, R. B., Reddy, E. P.

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SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA von QIN, Lihuai, FILIZOLA, Marta, JATIANI, Shashidhar, S, PAREKH, Samir, HU, Jianping, KUMAR, Prashasti, JAIN, Rinku, JIN, Jian, YU, Xufen, MENG, Fanye, SHEN, Yudao, ZHANG, Chengwei, KAPOOR, Abhijeet, KANISKAN, H., Umit, HAN, Yulin, AGGARWAL, Aneel, LEE, Clement

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