Ionizing radiation sensitizes tumors to PD-L1 immune checkpoint blockade in orthotopic murine head and neck squamous cell carcinoma von Oweida, Ayman, Lennon, Shelby, Calame, Dylan, Korpela, Sean, Bhatia, Shilpa, Sharma, Jaspreet, Graham, Caleb, Binder, David, Serkova, Natalie, Raben, David, Heasley, Lynn, Clambey, Eric, Nemenoff, Raphael, Karam, Sana D.

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Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions von Rushing, Blake R, Fogle, Halle M, Sharma, Jaspreet, You, Mikyoung, McCormac, Jonathan P, Molina, Sabrina, Sumner, Susan, Krupenko, Natalia I, Krupenko, Sergey A

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EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment von Bhatia, Shilpa, Nguyen, Diemmy, Darragh, Laurel B., Van Court, Benjamin, Sharma, Jaspreet, Knitz, Michael W., Piper, Miles, Bukkapatnam, Sanjana, Gadwa, Jacob, Bickett, Thomas E., Bhuvane, Shiv, Corbo, Sophia, Wu, Brian, Lee, Yichien, Fujita, Mayumi, Joshi, Molishree, Heasley, Lynn E., Ferris, Robert L., Rodriguez, Olga, Albanese, Christopher, Kapoor, Mohit, Pasquale, Elena B., Karam, Sana D.

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Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder von Krupenko, Natalia I, Sharma, Jaspreet, Pediaditakis, Peter, Helke, Kristi L, Hall, Madeline S, Du, Xiuxia, Sumner, Susan, Krupenko, Sergey A

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Knockout of Putative Tumor Suppressor Aldh1l1 in Mice Reprograms Metabolism to Accelerate Growth of Tumors in a Diethylnitrosamine (DEN) Model of Liver Carcinogenesis von Krupenko, Natalia I., Sharma, Jaspreet, Fogle, Halle M., Pediaditakis, Peter, Strickland, Kyle C., Du, Xiuxia, Helke, Kristi L., Sumner, Susan, Krupenko, Sergey A.

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Sex-Specific Metabolic Effects of Dietary Folate Withdrawal in Wild-Type and Aldh1l1 Knockout Mice von Sharma, Jaspreet, Rushing, Blake R, Hall, Madeline S, Helke, Kristi L, McRitchie, Susan L, Krupenko, Natalia I, Sumner, Susan J, Krupenko, Sergey A

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Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma von Bhatia, Shilpa, Hirsch, Kellen, Bukkapatnam, Sanjana, Baig, Nimrah A, Oweida, Ayman, Griego, Anastacia, Calame, Dylan, Sharma, Jaspreet, Donson, Andrew, Foreman, Nicholas, Albanese, Christopher, Venkataraman, Sujatha, Vibhakar, Rajeev, Karam, Sana D

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Folate pathways mediating the effects of ethanol in tumorigenesis von Sharma, Jaspreet, Krupenko, Sergey A.

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Metabolic Effects of ALDH1L1 Knockout in Diethylnitrosamine‐Induced Model of Liver Carcinogenesis von Sharma, Jaspreet, Krupenko, Natalia, Sumner, Susan, Krupenko, Sergey

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Impact of Aldh1l1 Knockout On Metabolic Phenotype in Mouse Liver von Sharma, Jaspreet, Krupenko, Natalia I., Krupenko, Sergey A.

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Abstract 2257: Effect ofALDH1L1folate enzyme on hepatocellular carcinoma inachemical carcinogenesismodel von Sharma, Jaspreet, Krupenko, Natalia I., Pediaditakis, Peter, Helke, Kristi, Strickland, Kyle C., Krupenko, Sergey A.

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Effects of Aldh1l2 Knockout on the Metabolic Profile of Mouse Liver von Sharma, Jaspreet, Krupenko, Natalia I., Sumner, Susan, Helke, Kristi L., Krupenko, Sergey A.

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Is ALDH1L1 Elevated in Lung Cancer? Comment on: Lee, S.-H.; et al. "The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung... von Krupenko, Sergey A, Sharma, Jaspreet

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Inhibition of EphB4-Ephrin-B2 Signaling Enhances Response to Cetuximab-Radiation Therapy in Head and Neck Cancers von Bhatia, Shilpa, Sharma, Jaspreet, Bukkapatnam, Sanjana, Oweida, Ayman, Lennon, Shelby, Phan, Andy, Milner, Dallin, Uyanga, Nomin, Jimeno, Antonio, Raben, David, Somerset, Hilary, Heasley, Lynn, Karam, Sana D

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Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver von Krupenko, Natalia I., Sharma, Jaspreet, Pediaditakis, Peter, Fekry, Baharan, Helke, Kristi L., Du, Xiuxia, Sumner, Susan, Krupenko, Sergey A.

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Abstract LB_B09: Loss of folate enzyme ALDH1L1 promotes cancer cell proliferation and xenograft tumor growth von Fogle, Halle M, You, Mikyoung, Sharma, Jaspreet, McCormac, Jonathan, Krupenko, Natalia I, Krupenko, Sergey A

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Effect of Folate Diet on Liver Metabolomics in Wild Type and Aldh1l1 Knockout Mice von Sharma, Jaspreet, Rushing, Blake, Krupenko, Natalia, Sumner, Susan, Krupenko, Sergey

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P10-029-23 ALDH1L2 Controls High-Fat Diet Induced Obesity-Linked Pathways in Female Mice von You, Mikyoung, Sharma, Jaspreet, Fogle, Halle, McCormac, Jonathan Parker, Krupenko, Natalia, Krupenko, Sergey

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Ephrin‐B2 overexpression predicts for poor prognosis and response to therapy in solid tumors von Oweida, Ayman, Bhatia, Shilpa, Hirsch, Kellen, Calame, Dylan, Griego, Anastacia, Keysar, Steve, Pitts, Todd, Sharma, Jaspreet, Eckhardt, Gail, Jimeno, Antonio, Wang, Xiao Jing, Parkash, Gill, Califano, Joseph, Karam, Sana D.

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Role of EphB3 Receptor in Mediating Head and Neck Tumor Growth, Cell Migration, and Response to PI3K Inhibitor von Bhatia, Shilpa, Griego, Anastacia, Lennon, Shelby, Oweida, Ayman, Sharma, Jaspreet, Rohmer, Christina, Uyanga, Nomin, Bukkapatnam, Sanjana, Van Court, Benjamin, Raben, David, Young, Christian, Heasley, Lynn, Karam, Sana D

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