27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology von Nelson, Erik R., Wardell, Suzanne E., Jasper, Jeff S., Park, Sunghee, Suchindran, Sunil, Howe, Matthew K., Carver, Nicole J., Pillai, Ruchita V., Sullivan, Patrick M., Sondhi, Varun, Umetani, Michihisa, Geradts, Joseph, McDonnell, Donald P.

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ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer von Park, Sunghee, Chang, Ching-Yi, Safi, Rachid, Liu, Xiaojing, Baldi, Robert, Jasper, Jeff S., Anderson, Grace R., Liu, Tingyu, Rathmell, Jeffrey C., Dewhirst, Mark W., Wood, Kris C., Locasale, Jason W., McDonnell, Donald P.

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The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer von Chang, Ching-yi, Kazmin, Dmitri, Jasper, Jeff S., Kunder, Rebecca, Zuercher, William J., McDonnell, Donald P.

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ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling von Wang, Jun, Rouse, Clay, Jasper, Jeff S, Pendergast, Ann Marie

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Systematic identification of signaling pathways with potential to confer anticancer drug resistance von Martz, Colin A, Ottina, Kathleen A, Singleton, Katherine R, Jasper, Jeff S, Wardell, Suzanne E, Peraza-Penton, Ashley, Anderson, Grace R, Winter, Peter S, Wang, Tim, Alley, Holly M, Kwong, Lawrence N, Cooper, Zachary A, Tetzlaff, Michael, Chen, Pei-Ling, Rathmell, Jeffrey C, Flaherty, Keith T, Wargo, Jennifer A, McDonnell, Donald P, Sabatini, David M, Wood, Kris C

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The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer von Cocce, Kimberly J., Jasper, Jeff S., Desautels, Taylor K., Everett, Logan, Wardell, Suzanne, Westerling, Thomas, Baldi, Robert, Wright, Tricia M., Tavares, Kendall, Yllanes, Alex, Bae, Yeeun, Blitzer, Jeremy T., Logsdon, Craig, Rakiec, Daniel P., Ruddy, David A., Jiang, Tiancong, Broadwater, Gloria, Hyslop, Terry, Hall, Allison, Laine, Muriel, Phung, Linda, Greene, Geoffrey L., Martin, Lesley-Ann, Pancholi, Sunil, Dowsett, Mitch, Detre, Simone, Marks, Jeffrey R., Crawford, Gregory E., Brown, Myles, Norris, John D., Chang, Ching-yi, McDonnell, Donald P.

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Distinct Receptor Tyrosine Kinase Subsets Mediate Anti-HER2 Drug Resistance in Breast Cancer von Alexander, Peter B., Chen, Rui, Gong, Chang, Yuan, Lifeng, Jasper, Jeff S., Ding, Yi, Markowitz, Geoffrey J., Yang, Pengyuan, Xu, Xin, McDonnell, Donald P., Song, Erwei, Wang, Xiao-Fan

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Delineation of a FOXA1/ERα/AGR2 regulatory loop that is dysregulated in endocrine therapy-resistant breast cancer von Wright, Tricia M, Wardell, Suzanne E, Jasper, Jeff S, Stice, James P, Safi, Rachid, Nelson, Erik R, McDonnell, Donald P

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Lysine-Specific Histone Demethylase 1 Inhibitors Control Breast Cancer Proliferation in ERα-Dependent and -Independent Manners von Pollock, Julie A, Larrea, Michelle D, Jasper, Jeff S, McDonnell, Donald P, McCafferty, Dewey G

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Abstract 312: Evidence of EZH2 dependent and independent mechanisms of tazemetostat treatment emergent resistance in models of diffuse large B cell lymphoma von Campbell, Carly T., Jasper, Jeff S., Daigle, Scott R., Ribich, Scott A., Keilhack, Heike, Smith, Jesse S., Ho, Peter T., Blakemore, Stephen J.

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Abstract B08: Tipping the balance: Factors that influence the ER signaling network in breast cancer von Jasper, Jeff S.

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The metabolic regulator ERRα, a downstream target of HER2/IGF-1, as a therapeutic target in breast cancer von Chang, Ching-yi, Kazmin, Dmitri, Jasper, Jeff S., Kunder, Rebecca, Zuercher, William J., McDonnell, Donald P.

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Coherent optical wavelength conversion via cavity optomechanics von Hill, Jeff T., Safavi-Naeini, Amir H., Chan, Jasper, Painter, Oskar

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Two-dimensional phononic-photonic band gap optomechanical crystal cavity von Safavi-Naeini, Amir H, Hill, Jeff T, Meenehan, Seán, Chan, Jasper, Gröblacher, Simon, Painter, Oskar

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Neuroimaging of the bilingual brain: Structural brain correlates of listening and speaking in a second language von Kuhl, Patricia K., Stevenson, Jeff, Corrigan, Neva M., van den Bosch, Jasper J.F., Can, Dilara Deniz, Richards, Todd

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Observation of quantum motion of a nanomechanical resonator von Safavi-Naeini, Amir H, Chan, Jasper, Hill, Jeff T, Alegre, Thiago P Mayer, Krause, Alex, Painter, Oskar

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Squeezed light from a silicon micromechanical resonator von Safavi-Naeini, Amir H., Gröblacher, Simon, Hill, Jeff T., Chan, Jasper, Aspelmeyer, Markus, Painter, Oskar

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Highly efficient coupling from an optical fiber to a nanoscale silicon optomechanical cavity von Gröblacher, Simon, Hill, Jeff T., Safavi-Naeini, Amir H., Chan, Jasper, Painter, Oskar

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Optimized optomechanical crystal cavity with acoustic radiation shield von Chan, Jasper, Safavi-Naeini, Amir H., Hill, Jeff T., Meenehan, Seán, Painter, Oskar

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Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19 von Tiruthani, Karthik, Cruz‐Teran, Carlos, Chan, Jasper F. W., Ma, Alice, McSweeney, Morgan, Wolf, Whitney, Yuan, Shoufeng, Poon, Vincent K. M., Chan, Chris C. S., Botta, Lakshmi, Farrer, Brian, Stewart, Ian, Schaefer, Alison, Edelstein, Jasmine, Kumar, Priya, Arora, Harendra, Hutchins, Jeff T., Hickey, Anthony J., Yuen, Kwok‐Yung, Lai, Samuel K.

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