Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer von Reichert, Maximilian, Bakir, Basil, Moreira, Leticia, Pitarresi, Jason R., Feldmann, Karin, Simon, Lauren, Suzuki, Kensuke, Maddipati, Ravikanth, Rhim, Andrew D., Schlitter, Anna M., Kriegsmann, Mark, Weichert, Wilko, Wirth, Matthias, Schuck, Kathleen, Schneider, Günter, Saur, Dieter, Reynolds, Albert B., Klein-Szanto, Andres J., Pehlivanoglu, Burcin, Memis, Bahar, Adsay, N. Volkan, Rustgi, Anil K.

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EMT, MET, Plasticity, and Tumor Metastasis von Bakir, Basil, Chiarella, Anna M., Pitarresi, Jason R., Rustgi, Anil K.

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MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma von Maddipati, Ravikanth, Norgard, Robert J, Baslan, Timour, Rathi, Komal S, Zhang, Amy, Saeid, Asal, Higashihara, Taku, Wu, Feng, Kumar, Angad, Annamalai, Valli, Bhattacharya, Saurav, Raman, Pichai, Adkisson, Christian A, Pitarresi, Jason R, Wengyn, Maximilian D, Yamazoe, Taiji, Li, Jinyang, Balli, David, LaRiviere, Michael J, Ngo, Tuong-Vi C, Folkert, Ian W, Millstein, Ian D, Bermeo, Jonathan, Carpenter, Erica L, McAuliffe, John C, Oktay, Maja H, Brekken, Rolf A, Lowe, Scott W, Iacobuzio-Donahue, Christine A, Notta, Faiyaz, Stanger, Ben Z

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Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer von Karakasheva, Tatiana A., Gabre, Joel T., Sachdeva, Uma M., Cruz-Acuña, Ricardo, Lin, Eric W., DeMarshall, Maureen, Falk, Gary W., Ginsberg, Gregory G., Yang, Zhaohai, Kim, Michele M., Diffenderfer, Eric S., Pitarresi, Jason R., Li, Jinyang, Muir, Amanda B., Hamilton, Kathryn E., Nakagawa, Hiroshi, Bass, Adam J., Rustgi, Anil K.

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PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability von Pitarresi, Jason R., Norgard, Robert J., Chiarella, Anna M., Suzuki, Kensuke, Bakir, Basil, Sahu, Varun, Li, Jinyang, Zhao, Jun, Marchand, Benoit, Wengyn, Maximilian D., Hsieh, Antony, Kim, Il-Kyu, Zhang, Amy, Sellin, Karine, Lee, Vivian, Takano, Shigetsugu, Miyahara, Yoji, Ohtsuka, Masayuki, Maitra, Anirban, Notta, Faiyaz, Kremer, Richard, Stanger, Ben Z., Rustgi, Anil K.

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Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains von Park, Dongju, Shakya, Reena, Koivisto, Christopher, Pitarresi, Jason R, Szabolcs, Matthias, Kladney, Raleigh, Hadjis, Ashley, Mace, Thomas A, Ludwig, Thomas

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Mutant p53 regulates Survivin to foster lung metastasis von Tang, Qiaosi, Efe, Gizem, Chiarella, Anna M., Leung, Jessica, Chen, Maoting, Yamazoe, Taiji, Su, Zhenyi, Pitarresi, Jason R., Li, Jinyang, Islam, Mirazul, Karakasheva, Tatiana, Klein-Szanto, Andres J., Pan, Samuel, Hu, Jianhua, Natsugoe, Shoji, Gu, Wei, Stanger, Ben Z., Wong, Kwok-K, Diehl, J. Alan, Bass, Adam J., Nakagawa, Hiroshi, Murphy, Maureen E., Rustgi, Anil K.

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Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice von Assouline, Benjamin, Kahn, Rachel, Hodali, Lutfi, Condiotti, Reba, Engel, Yarden, Elyada, Ela, Mordechai-Heyn, Tzlil, Pitarresi, Jason R., Atias, Dikla, Steinberg, Eliana, Bidany-Mizrahi, Tirza, Forkosh, Esther, Katz, Lior H., Benny, Ofra, Golan, Talia, Hofree, Matan, Stewart, Sheila A., Atlan, Karine A., Zamir, Gideon, Stanger, Ben Z., Berger, Michael, Ben-Porath, Ittai

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The ETS family of oncogenic transcription factors in solid tumours von Sizemore, Gina M., Pitarresi, Jason R., Balakrishnan, Subhasree, Ostrowski, Michael C.

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Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele von Wu, Jinghai, Liu, Xin, Nayak, Sunayana G, Pitarresi, Jason R, Cuitiño, Maria C, Yu, Lianbo, Hildreth, 3rd, Blake E, Thies, Katie A, Schilling, Daniel J, Fernandez, Soledad A, Leone, Gustavo, Ostrowski, Michael C

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IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer von Mace, Thomas A, Shakya, Reena, Pitarresi, Jason R, Swanson, Benjamin, McQuinn, Christopher W, Loftus, Shannon, Nordquist, Emily, Cruz-Monserrate, Zobeida, Yu, Lianbo, Young, Gregory, Zhong, Xiaoling, Zimmers, Teresa A, Ostrowski, Michael C, Ludwig, Thomas, Bloomston, Mark, Bekaii-Saab, Tanios, Lesinski, Gregory B

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Unmasking immune suppression von Pitarresi, Jason R, Fitzgerald, Katherine A

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Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia von Pitarresi, Jason R, Liu, Xin, Sharma, Sudarshana M, Cuitiño, Maria C, Kladney, Raleigh D, Mace, Thomas A, Donohue, Sydney, Nayak, Sunayana G, Qu, Chunjing, Lee, James, Woelke, Sarah A, Trela, Stefan, LaPak, Kyle, Yu, Lianbo, McElroy, Joseph, Rosol, Thomas J, Shakya, Reena, Ludwig, Thomas, Lesinski, Gregory B, Fernandez, Soledad A, Konieczny, Stephen F, Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C

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STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer von Lefler, Julia E, MarElia-Bennett, Catherine B, Thies, Katie A, Hildreth, 3rd, Blake E, Sharma, Sudarshana M, Pitarresi, Jason R, Han, Lu, Everett, Caroline, Koivisto, Christopher, Cuitino, Maria C, Timmers, Cynthia D, O'Quinn, Elizabeth, Parrish, Melodie, Romeo, Martin J, Linke, Amanda J, Hobbs, G Aaron, Leone, Gustavo, Guttridge, Denis C, Zimmers, Teresa A, Lesinski, Gregory B, Ostrowski, Michael C

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The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation von Fernandez Garcia, Emily, Paudel, Usha, Noji, Michael C., Bowman, Caitlyn E., Rustgi, Anil K., Pitarresi, Jason R., Wellen, Kathryn E., Arany, Zolt, Weissenrieder, Jillian S., Foskett, J. Kevin

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Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration von Giroux, Véronique, Lento, Ashley A., Islam, Mirazul, Pitarresi, Jason R., Kharbanda, Akriti, Hamilton, Kathryn E., Whelan, Kelly A., Long, Apple, Rhoades, Ben, Tang, Qiaosi, Nakagawa, Hiroshi, Lengner, Christopher J., Bass, Adam J., Wileyto, E. Paul, Klein-Szanto, Andres J., Wang, Timothy C., Rustgi, Anil K.

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Pancreatic plasticity: Unlocking exocrine lineage specification von Pitarresi, Jason R., Rustgi, Anil K.

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FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia von Li, Alina L., Sugiura, Kensuke, Nishiwaki, Noriyuki, Suzuki, Kensuke, Sadeghian, Dorsay, Zhao, Jun, Maitra, Anirban, Falvo, David, Chandwani, Rohit, Pitarresi, Jason R., Sims, Peter A., Rustgi, Anil K.

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PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells von Marchand, Benoît, Pitarresi, Jason R., Reichert, Maximilian, Suzuki, Kensuke, Laczkó, Dorottya, Rustgi, Anil K.

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Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration von Giroux, Véronique, Lento, Ashley A, Islam, Mirazul, Pitarresi, Jason R, Kharbanda, Akriti, Hamilton, Kathryn E, Whelan, Kelly A, Long, Apple, Rhoades, Ben, Tang, Qiaosi, Nakagawa, Hiroshi, Lengner, Christopher J, Bass, Adam J, Wileyto, E Paul, Klein-Szanto, Andres J, Wang, Timothy C, Rustgi, Anil K

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