LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response von Serganova, Inna, Cohen, Ivan J, Vemuri, Kiranmayi, Shindo, Masahiro, Maeda, Masatomo, Mane, Mayuresh, Moroz, Ekaterina, Khanin, Raya, Satagopan, Jaya, Koutcher, Jason A, Blasberg, Ronald

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Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer von Leftin, Avigdor, Ben-Chetrit, Nir, Klemm, Florian, Joyce, Johanna A, Koutcher, Jason A

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The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma von Nargund, Amrita M., Pham, Can G., Dong, Yiyu, Wang, Patricia I., Osmangeyoglu, Hatice U., Xie, Yuchen, Aras, Omer, Han, Song, Oyama, Toshinao, Takeda, Shugaku, Ray, Chelsea E., Dong, Zhenghong, Berge, Mathieu, Hakimi, A. Ari, Monette, Sebastien, Lekaye, Carl L., Koutcher, Jason A., Leslie, Christina S., Creighton, Chad J., Weinhold, Nils, Lee, William, Tickoo, Satish K., Wang, Zhong, Cheng, Emily H., Hsieh, James J.

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Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment von Simões, Rui V, Serganova, Inna S, Kruchevsky, Natalia, Leftin, Avigdor, Shestov, Alexander A, Thaler, Howard T, Sukenick, George, Locasale, Jason W, Blasberg, Ronald G, Koutcher, Jason A, Ackerstaff, Ellen

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Distinguishing metastatic triple‐negative breast cancer from nonmetastatic breast cancer using second harmonic generation imaging and resonance Raman spectroscopy von Bendau, Ethan, Smith, Jason, Zhang, Lin, Ackerstaff, Ellen, Kruchevsky, Natalia, Wu, Binlin, Koutcher, Jason A., Alfano, Robert, Shi, Lingyan

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Relationships between LDH-A, Lactate, and Metastases in 4T1 Breast Tumors von RIZWAN, Asif, SERGANOVA, Inna, KHANIN, Raya, KARABEBER, Hazem, XIAOHUI NI, THAKUR, Sunitha, ZAKIAN, Kristen L, BLASBERG, Ronald, KOUTCHER, Jason A

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Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury von Bodo, Sahra, Campagne, Cécile, Thin, Tin Htwe, Higginson, Daniel S, Vargas, H Alberto, Hua, Guoqiang, Fuller, John D, Ackerstaff, Ellen, Russell, James, Zhang, Zhigang, Klingler, Stefan, Cho, HyungJoon, Kaag, Matthew G, Mazaheri, Yousef, Rimner, Andreas, Manova-Todorova, Katia, Epel, Boris, Zatcky, Joan, Cleary, Cristian R, Rao, Shyam S, Yamada, Yoshiya, Zelefsky, Michael J, Halpern, Howard J, Koutcher, Jason A, Cordon-Cardo, Carlos, Greco, Carlo, Haimovitz-Friedman, Adriana, Sala, Evis, Powell, Simon N, Kolesnick, Richard, Fuks, Zvi

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ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer von Aytes, Alvaro, Mitrofanova, Antonina, Kinkade, Carolyn Waugh, Lefebvre, Celine, Lei, Ming, Phelan, Vanessa, LeKaye, H Carl, Koutcher, Jason A, Cardiff, Robert D, Califano, Andrea, Shen, Michael M, Abate-Shen, Cory

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Phase I Study of Intravenous Vascular Endothelial Growth Factor Trap, Aflibercept, in Patients With Advanced Solid Tumors von LOCKHART, A. Craig, ROTHENBERG, Mace L, GULTEKIN, David H, KOUTCHER, Jason A, DONNELLY, Edwin F, ANDAL, Ric, DANCY, Isabelle, SPRIGGS, David R, TEW, William P, DUPONT, Jakob, COOPER, Wendy, CHEVALIER, Paul, STERNAS, Lars, BUZENET, Giliane, KOEHLER, Elizabeth, SOSMAN, Jeffrey A, SCHWARTZ, Lawrence H

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Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment von Rattigan, Yanique I., Patel, Brijesh B., Ackerstaff, Ellen, Sukenick, George, Koutcher, Jason A., Glod, John W., Banerjee, Debabrata

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Metabolic Imaging: A Link between Lactate Dehydrogenase A, Lactate, and Tumor Phenotype von SERGANOVA, Inna, RIZWAN, Asif, XIAOHUI NI, THAKUR, Sunitha B, VIDER, Jelena, RUSSELL, James, BLASBERG, Ronald, KOUTCHER, Jason A

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Extension of the intravoxel incoherent motion model to non-gaussian diffusion in head and neck cancer von Lu, Yonggang, Jansen, Jacobus F.A., Mazaheri, Yousef, Stambuk, Hilda E., Koutcher, Jason A., Shukla-Dave, Amita

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Tumor stroma interaction is mediated by monocarboxylate metabolism von Patel, Brijesh B., Ackerstaff, Ellen, Serganova, Inna S., Kerrigan, John E., Blasberg, Ronald G., Koutcher, Jason A., Banerjee, Debabrata

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Inhibition of prostate cancer proliferation by Deferiprone von Simões, Rui V., Veeraperumal, Suresh, Serganova, Inna S., Kruchevsky, Natalia, Varshavsky, Joseph, Blasberg, Ronald G., Ackerstaff, Ellen, Koutcher, Jason A.

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Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Predictor of Outcome in Head-and-Neck Squamous Cell Carcinoma Patients With Nodal Metastases von Shukla-Dave, Amita, Ph.D, Lee, Nancy Y., M.D, Jansen, Jacobus F.A., Ph.D, Thaler, Howard T., Ph.D, Stambuk, Hilda E., M.D, Fury, Matthew G., M.D, Patel, Snehal G., M.D, Moreira, Andre L., M.D, Sherman, Eric, M.D, Karimi, Sasan, M.D, Wang, Ya, M.S, Kraus, Dennis, M.D, Shah, Jatin P., M.D, Pfister, David G., M.D, Koutcher, Jason A., M.D., Ph.D

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Pten dose dictates cancer progression in the prostate von Trotman, Lloyd C, Niki, Masaru, Dotan, Zohar A, Koutcher, Jason A, Di Cristofano, Antonio, Xiao, Andrew, Khoo, Alan S, Roy-Burman, Pradip, Greenberg, Norman M, Van Dyke, Terry, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo

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Towards multidimensional radiotherapy (MD-CRT): biological imaging and biological conformality von Ling, C.Clifton, Humm, John, Larson, Steven, Amols, Howard, Fuks, Zvi, Leibel, Steven, Koutcher, Jason A

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Discrimination of Benign and Malignant Breast Lesions by Using Shutter-Speed Dynamic Contrast-enhanced MR Imaging von WEI HUANG, TUDORICA, Luminita A, SPRINGER, Charles S, XIN LI, THAKUR, Sunitha B, YIYI CHEN, MORRIS, Elizabeth A, TAGGE, Ian J, KORENBLIT, Maayan E, ROONEY, William D, KOUTCHER, Jason A

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Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer von Viola-villegas, Nerissa Therese, Carlin, Sean D., Ackerstaff, Ellen, Sevak, Kuntal K., Divilov, Vadim, Serganova, Inna, Kruchevsky, Natalia, Anderson, Michael, Blasberg, Ronald G., Andreev, Oleg A., Engelman, Donald M., Koutcher, Jason A., Reshetnyak, Yana K., Lewis, Jason S.

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Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors von Regales, Lucia, Balak, Marissa N, Gong, Yixuan, Politi, Katerina, Sawai, Ayana, Le, Carl, Koutcher, Jason A, Solit, David B, Rosen, Neal, Zakowski, Maureen F, Pao, William

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