Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval von Jardim, Denis L, Fontes Jardim, Denis L, Schwaederle, Maria, Wei, Caimiao, Lee, J Jack, Hong, David S, Eggermont, Alexander M, Schilsky, Richard L, Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle

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Factors Associated with Failure of Oncology Drugs in Late-Stage Clinical Development: a Systematic Review von Fontes Jardim, Denis L, Groves, Eric S, Breitfeld, Philip P, Kurzrock, Razelle

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The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker von Jardim, Denis L., Goodman, Aaron, de Melo Gagliato, Debora, Kurzrock, Razelle

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Phosphatidylinositol 3‐kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities von Millis, Sherri Z., Jardim, Denis L., Albacker, Lee, Ross, Jeffrey S., Miller, Vincent A., Ali, Siraj M., Kurzrock, Razelle

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MET alterations detected in blood-derived circulating tumor DNA correlate with bone metastases and poor prognosis von Ikeda, Sadakatsu, Schwaederle, Maria, Mohindra, Mandakini, Fontes Jardim, Denis L, Kurzrock, Razelle

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Adjustable, (super)hydrophobicity by e-beam deposition of nanostructured PTFE on textured silicon surfaces von Michels, A. F, Soave, P. A, Nardi, J, Jardim, P. L. G, Teixeira, S. R, Weibel, D. E, Horowitz, F

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Diet disparity and diversity predict extinction risk in primates von Machado, F. F., Jardim, L., Dinnage, R., Brito, D., Cardillo, M.

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Oxaliplatin-related thrombocytopenia von Jardim, D.L., Rodrigues, C.A., Novis, Y.A.S., Rocha, V.G., Hoff, P.M.

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The Clinical and Molecular Profile of Lung Cancer Patients Harboring the TP53 R337H Germline Variant in a Brazilian Cancer Center: The Possible Mechanism of Carcinogenesis von Lopes, Carlos D. H., Antonacio, Fernanda F., Moraes, Priscila M. G., Asprino, Paula F., Galante, Pedro A. F., Jardim, Denis L., de Macedo, Mariana P., Sandoval, Renata L., Katz, Artur, de Castro, Gilberto, Achatz, Maria Isabel

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Variation of rs3754689 at lactase gene and inhibitors in admixed Brazilian patients with hemophilia A von Zuccherato, Luciana W, Elói-Santos, Silvana M, Jardim, Letícia L, Camelo, Ricardo M, Chaves, Daniel G, Souza, Renan P, Hollox, Edward J, Rezende, Suely M

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Choice of 16S Ribosomal RNA Primers Impacts Male Urinary Microbiota Profiling von Heidrich, Vitor, Inoue, Lilian T, Asprino, Paula F, Bettoni, Fabiana, Mariotti, Antonio C H, Bastos, Diogo A, Jardim, Denis L F, Arap, Marco A, Camargo, Anamaria A

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[OP.3B.07] MULTIDISCIPLINARY TREATMENT FOR THE VERY ELDERLY HYPERTENSIVE PATIENT von Jardim, T, Jardim, L, Sousa, A, Barroso, W, Pimenta, C, Jardim, P

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MR Imaging in Spinocerebellar Ataxias: A Systematic Review von Klaes, A, Reckziegel, E, Franca, Jr, M C, Rezende, T J R, Vedolin, L M, Jardim, L B, Saute, J A

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FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors von Jardim, Denis L, Wheler, Jennifer J, Hess, Kenneth, Tsimberidou, Apostolia M, Zinner, Ralph, Janku, Filip, Subbiah, Vivek, Naing, Aung, Piha-Paul, Sarina A, Westin, Shannon N, Roy-Chowdhuri, Sinchita, Meric-Bernstam, Funda, Hong, David S

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Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds von Jardim, Denis L., De Melo Gagliato, Débora, Nikanjam, Mina, Barkauskas, Donald A., Kurzrock, Razelle

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Analysis of 1,115 patients tested for MET amplification and therapy response in the MD Anderson Phase I Clinic von Jardim, Denis L F, Tang, Chad, Gagliato, Debora De Melo, Falchook, Gerald S, Hess, Kenneth, Janku, Filip, Fu, Siqing, Wheler, Jennifer J, Zinner, Ralph G, Naing, Aung, Tsimberidou, Apostolia M, Holla, Vijaykumar, Li, Marylin M, Roy-Chowdhuri, Sinchita, Luthra, Raja, Salgia, Ravi, Kurzrock, Razelle, Meric-Bernstam, Funda, Hong, David S

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Prevalence of sporadic haemophilia A von Santana, Márcio A. P., Chaves, Daniel G., Camelo, Ricardo M., Zuccherato, Luciana W., Jardim, Letícia L., Rezende, Suely M.

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Spinocerebellar ataxia type 3/Machado-Joseph disease: segregation patterns and factors influencing instability of expanded CAG transmissions von Souza, G.N., Kersting, N., Krum-Santos, A.C., Santos, A.S.P., Furtado, G.V., Pacheco, D., Gonçalves, T.A., Saute, J.A., Schuler-Faccini, L., Mattos, E.P., Saraiva-Pereira, M.L., Jardim, L.B.

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Persistence of Leishmania Parasites in Scars after Clinical Cure of American Cutaneous Leishmaniasis: Is There a Sterile Cure? von Mendonça, Mitzi G., de Brito, Maria E. F, Rodrigues, Eduardo H. G., Bandeira, Valdir, Jardim, Márcio L., Abath, Frederico G. C.

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Mitochondrial DNA haplogroups and age at onset of Machado–Joseph disease/spinocerebellar ataxia type 3: a study in patients from multiple populations von Ramos, A., Planchat, M., Vieira Melo, A. R., Raposo, M., Shamim, U., Suroliya, V., Srivastava, A. K., Faruq, M., Morino, H., Ohsawa, R., Kawakami, H., Bannach Jardim, L., Saraiva‐Pereira, M. L., Vasconcelos, J., Santos, C., Lima, M.

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