A Randomized Trial of the Effects of Nebulized Albuterol on Pulmonary Edema in Brain‐Dead Organ Donors von Ware, L. B., Landeck, M., Koyama, T., Zhao, Z., Singer, J., Kern, R., Neidlinger, N., Nguyen, J., Johnson, E., Janz, D. R., Bernard, G. R., Lee, J. W., Matthay, M. A.

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Nonlinear Imputation of PaO2/FIO2 From SpO2/FIO2 Among Mechanically Ventilated Patients in the ICU: A Prospective, Observational Study von Brown, Samuel M, Duggal, Abhijit, Hou, Peter C, Tidswell, Mark, Khan, Akram, Exline, Matthew, Park, Pauline K, Schoenfeld, David A, Liu, Ming, Grissom, Colin K, Moss, Marc, Rice, Todd W, Hough, Catherine L, Rivers, Emanuel, Thompson, B Taylor, Brower, Roy G

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Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress von Bastarache, Julie A, Sebag, Sara C, Clune, Jennifer K, Grove, Brandon S, Lawson, William E, Janz, David R, Roberts, L Jackson, Dworski, Ryszard, Mackman, Nigel, Ware, Lorraine B

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Distinct Molecular Phenotypes of Direct vs Indirect ARDS in Single-Center and Multicenter Studies von Calfee, Carolyn S., MD, MAS, Janz, David R., MD, Bernard, Gordon R., MD, FCCP, May, Addison K., MD, Kangelaris, Kirsten N., MD, MAS, Matthay, Michael A., MD, FCCP, Ware, Lorraine B., MD, FCCP, the NIH NHLBI ARDS Network

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A25 CRITICAL CARE: HOW TO GET IT DONE IN THE ICU - TOOLS AND TRICKS OF IMPLEMENTATION IN CRITICAL CARE: A Multicenter, Randomized Trial Of A Pre-Procedure Checklist For Endotrachea... von Janz, D R, Semler, M W, Joffee, A, Casey, J D, Lentz, R J, DeBoisblanc, B P, Khan, Y A, Santanilla, J I, Rice, T W

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A42 ARDS: RISK, TREATMENT, AND OUTCOMES: Clinical Characteristics And Outcomes Are Similar In Ards Diagnosed By The Spo2/fio2 Ratio Compared With The Pao2/fio2 Ratio von Chen, W, Janz, D R, Shaver, C M, Bastarache, J A, Ware, L

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A25 CRITICAL CARE: HOW TO GET IT DONE IN THE ICU - TOOLS AND TRICKS OF IMPLEMENTATION IN CRITICAL CARE: Pressure-Targeted Modes Of Invasive Mechanical Ventilation Are Associated Wi... von Khan, Y A, Mooney, J L, McKown, A C, Semler, M W, Rice, T W, DeBoisblanc, B P, Janz, D R

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D14 NEW INSIGHTS INTO MECHANICAL VENTILATION: Early Exposure To Hyperoxia Is Not Associated With Mortality In Critically Ill Patients With Severe Traumatic Injuries von Russell, D W, Janz, D R, Emerson, W, Ware, L B

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C24 CRITICAL CARE: CAN ICU DESIGN IMPROVE ICU CARE?: Inter-Hospital Transport Of Critically Ill Adults During a Hospital Relocation Is Not Associated With Clinical Deterioration Or... von Khan, Y A, Johnson, J L, Mooney, J L, Barnes, R H, MacMahon, J, Holloway, V L, Semler, M W, Rice, T W, DeBoisblanc, B, Janz, D R

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B24 MECHANISMS OF INJURY IN SEPSIS: INFLAMMATION, OXIDATION, AND ENDOTHELIAL DAMAGE: Haptoglobin 2:2 Genotype Is Associated With Acute Respiratory Distress Syndrome And Acute Kidne... von Nagata, H, Janz, D R, Sills, G, Shaver, C M, Wickersham, N, Bastarache, J A, Ware, L B

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A42 ARDS: RISK, TREATMENT, AND OUTCOMES: Plasma Angiopoietin-2 (ang2) And Receptor For Advanced Glycation End Products (rage) Improve Diagnosis Of Ards Compared To Provider Clinica... von Brown, R M, Semler, M W, Zhao, Z, Koyama, T, Janz, D R, May, A K, Matthay, M A, Cohen, M J, Calfee, C S, Ware, L B

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A21 THE MESENCHYME AND THE EPITHELIUM IN AIRWAY INFLAMMATION: Cell-Free Hemoglobin Elicits A Pro-Inflammatory Response In Lung Epithelial Cells von Upchurch, C P, Grove, B S, Shaver, C M, Janz, D R, Ware, L B, Bastarache, J A

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B108 DIAGNOSTIC AND PROGNOSTIC ASSESSMENT OF PULMONARY VASCULAR DISEASE: Plasma Cell-Free Hemoglobin Levels Are Elevated In Pulmonary Arterial Hypertension And Associated With Wors... von Janz, D R, Brittain, E, Bastarache, J A, Koestner, N A, Botschner, D A, Wickersham, N, Sills, G, Su, Y R, Hemnes, A R, Ware, L B

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C44 CRITICAL ILLNESS PREDICTORS AND OUTCOMES: New-Onset Atrial Fibrillation Is Independently Associated With Increased Mortality In Critically Ill Patients von Shaver, C M, Chen, W, Janz, D R, May, A K, Bernard, G R, Darbar, D, Bastarache, J A, Ware, L B

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A19 LATE BREAKING ABSTRACTS IN CLINICAL TRIALS: Randomized Trial Of Acetaminophen For The Reduction Of Oxidative Injury In Patients With Severe Sepsis (across) von Janz, D R, Bastarache, J A, Rice, T W, Bernard, G R, Warren, M A, Wickersham, N, Sills, G, Oates, J A, Roberts, L J, Ware, L B

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B24 MECHANISMS OF INJURY IN SEPSIS: INFLAMMATION, OXIDATION, AND ENDOTHELIAL DAMAGE: Plasma Levels Of Oxidized Ferryl (4+) Hemoglobin Are Elevated In Severe Sepsis And Are Reduced... von Bastarache, J A, Janz, D R, Rice, T W, Bernard, G R, Warren, M A, Wickersham, N, Sills, G, Oates, J A, Roberts, L J, Dikalov, S I, Ware, L B

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Acetaminophen Improves Kidney Function in Severe Sepsis von Nichols, E. H., Janz, D. R.

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C106 IRON, HEMOLYSIS, AND INFLAMMATION: EFFECTS ON THE PULMONARY CIRCULATION: Acetaminophen Prevents Increases In Endothelial Permeability And Mitochondrial Superoxide Triggered By... von Kuck, J, Shaver, C M, May, J, Qu, Z-C, Dikalov, S I, Wickersham, N, Nagata, H, McNeil, J B, Putz, N, Roberts, L J, Janz, D R, Bastarache, J A, Ware, L B

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A25 LUNG INJURY: MARKERS AND OUTCOMES: The Rs35705950 Muc5b Promoter Polymorphism And Ards von Rogers, A J, Solus, J F, Hunninghake, G M, Baron, R M, Schwartz, D A, May, A K, Janz, D R, Lawson, W E, Blackwell, T S, Ware, L B

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Effect of Laryngoscope Blade Size on First Pass Success of Tracheal Intubation in Critically Ill Adults von Landefeld, Kevin R, Koike, Seiji, Ran, Ran, Semler, Matthew W, Barnes, Christopher, Stempek, Susan B, Janz, David R, Rice, Todd W, Russell, Derek W, Self, Wesley H, Vonderhaar, Derek, West, Jason R, Casey, Jonathan D, Khan, Akram

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