Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm von Nakamura, Yoshiaki, Kawazoe, Akihito, Lordick, Florian, Janjigian, Yelena Y., Shitara, Kohei

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Lapatinib in Gastric Cancer: What Is the LOGiCal Next Step? von Janjigian, Yelena Y

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The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer von Janjigian, Yelena Y., Kawazoe, Akihito, Yañez, Patricio, Li, Ning, Lonardi, Sara, Kolesnik, Oleksii, Barajas, Olga, Bai, Yuxian, Shen, Lin, Tang, Yong, Wyrwicz, Lucjan S., Xu, Jianming, Shitara, Kohei, Qin, Shukui, Van Cutsem, Eric, Tabernero, Josep, Li, Lie, Shah, Sukrut, Bhagia, Pooja, Chung, Hyun Cheol

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New agents on the horizon in gastric cancer von Lordick, F., Shitara, K., Janjigian, Y.Y.

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Nivolumab plus chemotherapy or ipilimumab in gastro-oesophageal cancer von Shitara, Kohei, Ajani, Jaffer A., Moehler, Markus, Garrido, Marcelo, Gallardo, Carlos, Shen, Lin, Yamaguchi, Kensei, Wyrwicz, Lucjan, Skoczylas, Tomasz, Bragagnoli, Arinilda Campos, Liu, Tianshu, Tehfe, Mustapha, Elimova, Elena, Bruges, Ricardo, Zander, Thomas, de Azevedo, Sergio, Kowalyszyn, Ruben, Pazo-Cid, Roberto, Schenker, Michael, Cleary, James M., Yanez, Patricio, Feeney, Kynan, Karamouzis, Michalis V., Poulart, Valerie, Lei, Ming, Xiao, Hong, Kondo, Kaoru, Li, Mingshun, Janjigian, Yelena Y.

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Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies von Harding, James J, Nandakumar, Subhiksha, Armenia, Joshua, Khalil, Danny N, Albano, Melanie, Ly, Michele, Shia, Jinru, Hechtman, Jaclyn F, Kundra, Ritika, El Dika, Imane, Do, Richard K, Sun, Yichao, Kingham, T Peter, D'Angelica, Michael I, Berger, Michael F, Hyman, David M, Jarnagin, William, Klimstra, David S, Janjigian, Yelena Y, Solit, David B, Schultz, Nikolaus, Abou-Alfa, Ghassan K

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Prognosis of metastatic gastric and gastroesophageal junction cancer by HER2 status: a European and USA International collaborative analysis von Janjigian, Y.Y., Werner, D., Pauligk, C., Steinmetz, K., Kelsen, D.P., Jäger, E., Altmannsberger, H.M., Robinson, E., Tafe, L.J., Tang, L.H., Shah, M.A., Al-Batran, S.-E.

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Safety and feasibility of esophagectomy following combined immunotherapy and chemoradiotherapy for esophageal cancer von Sihag, Smita, Ku, Geoffrey Y., Tan, Kay See, Nussenzweig, Samuel, Wu, Abraham, Janjigian, Yelena Y., Jones, David R., Molena, Daniela

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Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy von Pereira, Patrícia M. R., Sharma, Sai Kiran, Carter, Lukas M., Edwards, Kimberly J., Pourat, Jacob, Ragupathi, Ashwin, Janjigian, Yelena Y., Durack, Jeremy C., Lewis, Jason S.

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PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis von Yamaguchi, Norihiro, Weinberg, Ethan M, Nguyen, Alexander, Liberti, Maria V, Goodarzi, Hani, Janjigian, Yelena Y, Paty, Philip B, Saltz, Leonard B, Kingham, T Peter, Loo, Jia Min, de Stanchina, Elisa, Tavazoie, Sohail F

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Caveolin-1 temporal modulation enhances antibody drug efficacy in heterogeneous gastric cancer von Pereira, Patrícia M. R., Mandleywala, Komal, Monette, Sébastien, Lumish, Melissa, Tully, Kathryn M., Panikar, Sandeep Surendra, Cornejo, Mike, Mauguen, Audrey, Ragupathi, Ashwin, Keltee, Nai C., Mattar, Marissa, Janjigian, Yelena Y., Lewis, Jason S.

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MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer von Janjigian, Yelena Y, Van Cutsem, Eric, Muro, Kei, Wainberg, Zev, Al-Batran, Salah-Eddin, Hyung, Woo Jin, Molena, Daniela, Marcovitz, Michelle, Ruscica, Dario, Robbins, Scott H, Negro, Alejandra, Tabernero, Josep

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Molecular Classification of Gastric Cancer: A New Paradigm von SHAH, Manish A, KHANIN, Raya, TANG, Laura, JANJIGIAN, Yelena Y, KLIMSTRA, David S, GERDES, Hans, KELSEN, David P

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Outcomes of Neoadjuvant Chemotherapy for Clinical Stages 2 and 3 Gastric Cancer Patients: Analysis of Timing and Site of Recurrence von Nakauchi, Masaya, Vos, Elvira, Tang, Laura H., Gonen, Mithat, Janjigian, Yelena Y., Ku, Geoffrey Y., Ilson, David H., Maron, Steven B., Yoon, Sam S., Brennan, Murray F., Coit, Daniel G., Strong, Vivian E.

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Postoperative ctDNA monitoring: a canary in a coalmine von Lumish, M.A., Tarazona, N., Janjigian, Y.Y.

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Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition von Harding, James J, Lowery, Maeve A, Shih, Alan H, Schvartzman, Juan M, Hou, Shengqi, Famulare, Christopher, Patel, Minal, Roshal, Mikhail, Do, Richard K, Zehir, Ahmet, You, Daoqi, Selcuklu, S Duygu, Viale, Agnes, Tallman, Martin S, Hyman, David M, Reznik, Ed, Finley, Lydia W S, Papaemmanuil, Elli, Tosolini, Alessandra, Frattini, Mark G, MacBeth, Kyle J, Liu, Guowen, Fan, Bin, Choe, Sung, Wu, Bin, Janjigian, Yelena Y, Mellinghoff, Ingo K, Diaz, Luis A, Levine, Ross L, Abou-Alfa, Ghassan K, Stein, Eytan M, Intlekofer, Andrew M

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Comparison of Long- and Short-term Outcomes in 845 Open and Minimally Invasive Gastrectomies for Gastric Cancer in the United States von Nakauchi, Masaya, Vos, Elvira, Janjigian, Yelena Y., Ku, Geoffrey Y., Schattner, Mark A., Nishimura, Makoto, Gonen, Mithat, Coit, Daniel G., Strong, Vivian E.

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Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies von Murciano-Goroff, Yonina R., Schram, Alison M., Rosen, Ezra Y., Won, Helen, Gong, Yixiao, Noronha, Anne Marie, Janjigian, Yelena Y., Stadler, Zsofia K., Chang, Jason C., Yang, Soo-Ryum, Mandelker, Diana, Offit, Kenneth, Berger, Michael F., Donoghue, Mark T. A., Bandlamudi, Chaitanya, Drilon, Alexander

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Tumor mutational load predicts survival after immunotherapy across multiple cancer types von Samstein, Robert M., Lee, Chung-Han, Shoushtari, Alexander N., Hellmann, Matthew D., Shen, Ronglai, Janjigian, Yelena Y., Barron, David A., Zehir, Ahmet, Jordan, Emmet J., Omuro, Antonio, Kaley, Thomas J., Kendall, Sviatoslav M., Motzer, Robert J., Hakimi, A. Ari, Voss, Martin H., Russo, Paul, Rosenberg, Jonathan, Iyer, Gopa, Bochner, Bernard H., Bajorin, Dean F., Al-Ahmadie, Hikmat A., Chaft, Jamie E., Rudin, Charles M., Riely, Gregory J., Baxi, Shrujal, Ho, Alan L., Wong, Richard J., Pfister, David G., Wolchok, Jedd D., Barker, Christopher A., Gutin, Philip H., Brennan, Cameron W., Tabar, Viviane, Mellinghoff, Ingo K., DeAngelis, Lisa M., Ariyan, Charlotte E., Lee, Nancy, Tap, William D., Gounder, Mrinal M., D’Angelo, Sandra P., Saltz, Leonard, Stadler, Zsofia K., Scher, Howard I., Baselga, Jose, Razavi, Pedram, Klebanoff, Christopher A., Yaeger, Rona, Segal, Neil H., Ku, Geoffrey Y., DeMatteo, Ronald P., Ladanyi, Marc, Rizvi, Naiyer A., Berger, Michael F., Riaz, Nadeem, Solit, David B., Chan, Timothy A., Morris, Luc G. T.

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Distinct Clinical Course of EGFR-Mutant Resected Lung Cancers: Results of Testing of 1118 Surgical Specimens and Effects of Adjuvant Gefitinib and Erlotinib von D’Angelo, Sandra P., Janjigian, Yelena Y., Ahye, Nicholas, Riely, Gregory J., Chaft, Jamie E., Sima, Camelia S., Shen, Ronglai, Zheng, Junting, Dycoco, Joseph, Kris, Mark G., Zakowski, Maureen F., Ladanyi, Marc, Rusch, Valerie, Azzoli, Christopher G.

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