The value of GATA6 immunohistochemistry and computer-assisted diagnosis to predict clinical outcome in advanced pancreatic cancer von Duan, Kai, Jang, Gun-Ho, Grant, Robert C., Wilson, Julie M., Notta, Faiyaz, O’Kane, Grainne M., Knox, Jennifer J., Gallinger, Steven, Fischer, Sandra

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Mitochondrial fitness and cancer risk von Kossenkov, Andrew V, Milcarek, Andrew, Notta, Faiyaz, Jang, Gun-Ho, Wilson, Julie M, Gallinger, Steven, Zhou, Daniel Cui, Ding, Li, Ghosh, Jagadish C, Perego, Michela, Morotti, Annamaria, Locatelli, Marco, Robert, Marie E, Vaira, Valentina, Altieri, Dario C

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Relative Belief Inferences from Decision Theory von Evans, Michael, Jang, Gun Ho

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PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors von Deshwar, Amit G, Vembu, Shankar, Yung, Christina K, Jang, Gun Ho, Stein, Lincoln, Morris, Quaid

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Spatially confined sub-tumor microenvironments in pancreatic cancer von Grünwald, Barbara T., Devisme, Antoine, Andrieux, Geoffroy, Vyas, Foram, Aliar, Kazeera, McCloskey, Curtis W., Macklin, Andrew, Jang, Gun Ho, Denroche, Robert, Romero, Joan Miguel, Bavi, Prashant, Bronsert, Peter, Notta, Faiyaz, O’Kane, Grainne, Wilson, Julie, Knox, Jennifer, Tamblyn, Laura, Udaskin, Molly, Radulovich, Nikolina, Fischer, Sandra E., Boerries, Melanie, Gallinger, Steven, Kislinger, Thomas, Khokha, Rama

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Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity von Hezaveh, Kebria, Shinde, Rahul S, Klötgen, Andreas, Halaby, Marie Jo, Lamorte, Sara, Ciudad, M Teresa, Quevedo, Rene, Neufeld, Luke, Liu, Zhe Qi, Jin, Robbie, Grünwald, Barbara T, Foerster, Elisabeth G, Chaharlangi, Danica, Guo, Mengdi, Makhijani, Priya, Zhang, Xin, Pugh, Trevor J, Pinto, Devanand M, Co, Ileana L, McGuigan, Alison P, Jang, Gun Ho, Khokha, Rama, Ohashi, Pamela S, O'Kane, Grainne M, Gallinger, Steven, Navarre, William W, Maughan, Heather, Philpott, Dana J, Brooks, David G, McGaha, Tracy L

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GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer von O'Kane, Grainne M., Grunwald, Barbara T., Jang, Gun-Ho, Masoomian, Mehdi, Picardo, Sarah, Grant, Robert C., Denroche, Robert E., Zhang, Amy, Wang, Yifan, Lam, Bernard, Krzyzanowski, Paul M., Lungu, Illinca M., Bartlett, John M. S., Peralta, Melanie, Vyas, Foram, Khokha, Rama, Biagi, James, Chadwick, Dianne, Ramotar, Stephanie, Hutchinson, Shawn, Dodd, Anna, Wilson, Julie M., Notta, Faiyaz, Zogopoulos, George, Gallinger, Steven, Knox, Jennifer J., Fischer, Sandra E.

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Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial von Aung, Kyaw L, Fischer, Sandra E, Denroche, Robert E, Jang, Gun-Ho, Dodd, Anna, Creighton, Sean, Southwood, Bernadette, Liang, Sheng-Ben, Chadwick, Dianne, Zhang, Amy, O'Kane, Grainne M, Albaba, Hamzeh, Moura, Shari, Grant, Robert C, Miller, Jessica K, Mbabaali, Faridah, Pasternack, Danielle, Lungu, Ilinca M, Bartlett, John M S, Ghai, Sangeet, Lemire, Mathieu, Holter, Spring, Connor, Ashton A, Moffitt, Richard A, Yeh, Jen Jen, Timms, Lee, Krzyzanowski, Paul M, Dhani, Neesha, Hedley, David, Notta, Faiyaz, Wilson, Julie M, Moore, Malcolm J, Gallinger, Steven, Knox, Jennifer J

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Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma von Grant, Robert C, Denroche, Robert, Jang, Gun Ho, Nowak, Klaudia M, Zhang, Amy, Borgida, Ayelet, Holter, Spring, Topham, James T, Wilson, Julie, Dodd, Anna, Jang, Raymond, Prince, Rebecca, Karasinska, Joanna M, Schaeffer, David F, Wang, Yifan, Zogopoulos, George, Berry, Scott, Simeone, Diane, Renouf, Daniel J, Notta, Faiyaz, O'Kane, Grainne, Knox, Jennifer, Fischer, Sandra, Gallinger, Steven

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A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer von Romero, Joan M., Grunwald, Barbara, Jang, Gun-Ho, Bavi, Prashant P., Jhaveri, Aaditeya, Masoomian, Mehdi, Fischer, Sandra E., Zhang, Amy, Denroche, Robert E., Lungu, Ilinca M., De Luca, Angela, Bartlett, John M. S., Xu, Jing, Li, Niandong, Dhaliwal, Sharon, Liang, Sheng-Ben, Chadwick, Dianne, Vyas, Foram, Bronsert, Peter, Khokha, Rama, McGaha, Tracy L., Notta, Faiyaz, Ohashi, Pamela S., Done, Susan J., O'Kane, Grainne M., Wilson, Julie M., Knox, Jennifer J., Connor, Ashton, Wang, Yifan, Zogopoulos, George, Gallinger, Steven

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Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma von Golan, Talia, O’Kane, Grainne M., Denroche, Robert E., Raitses-Gurevich, Maria, Grant, Robert C., Holter, Spring, Wang, Yifan, Zhang, Amy, Jang, Gun Ho, Stossel, Chani, Atias, Dikla, Halperin, Sharon, Berger, Raanan, Glick, Yulia, Park, J. Patrick, Cuggia, Adeline, Williamson, Laura, Wong, Hui-Li, Schaeffer, David F., Renouf, Daniel J., Borgida, Ayelet, Dodd, Anna, Wilson, Julie M., Fischer, Sandra E., Notta, Faiyaz, Knox, Jennifer J., Zogopoulos, George, Gallinger, Steven

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Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes von Miyabayashi, Koji, Baker, Lindsey A., Deschenes, Astrid, Traub, Benno, Caligiuri, Giuseppina, Plenker, Dennis, Alagesan, Brinda, Belleau, Pascal, Li, Siran, Kendall, Jude, Jang, Gun Ho, Kawaguchi, Risa Karakida, Somerville, Tim D. D., Tiriac, Herve, Hwang, Chang-Il, Burkhart, Richard A., Roberts, Nicholas J., Wood, Laura D., Hruban, Ralph H., Gillis, Jesse, Krasnitz, Alexander, Vakoc, Christopher R., Wigler, Michael, Notta, Faiyaz, Gallinger, Steven, Park, Youngkyu, Tuveson, David A.

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GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinoma von de Andrés, Mónica P, Jackson, Richard J, Felipe, Irene, Zagorac, Sladjana, Pilarsky, Christian, Schlitter, Anna Melissa, Martinez de Villareal, Jaime, Jang, Gun Ho, Costello, Eithne, Gallinger, Steve, Ghaneh, Paula, Greenhalf, William, Knösel, Thomas, Palmer, Daniel H, Ruemmele, Petra, Weichert, Wilko, Buechler, Markus, Hackert, Thilo, Neoptolemos, John P, Notta, Faiyaz, Malats, Núria, Martinelli, Paola, Real, Francisco X

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Molecular characterisation of pancreatic ductal adenocarcinoma with NTRK fusions and review of the literature von Allen, Michael J, Zhang, Amy, Bavi, Prashant, Kim, Jaeseung C, Jang, Gun Ho, Kelly, Deirdre, Perera, Sheron, Denroche, Rob E, Notta, Faiyaz, Wilson, Julie M, Dodd, Anna, Ramotar, Stephanie, Hutchinson, Shawn, Fischer, Sandra E, Grant, Robert C, Gallinger, Steven, Knox, Jennifer J, O'Kane, Grainne M

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Hourglass, a rapid analysis framework for heterogeneous bioimaging data, identifies sex disparity in IL-6/STAT3-associated immune phenotypes in pancreatic cancer von Aliar, Kazeera, Waterhouse, Henry R, Vyas, Foram, Krebs, Niklas, Zhang, Bowen, Poulton, Emily, Chan, Nathan, Gonzalez, Ricardo, Jang, Gun Ho, Bronsert, Peter, Fischer, Sandra E, Gallinger, Steven, Grünwald, Barbara T, Khokha, Rama

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In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer von Martinez, Sebastien, Wu, Shifei, Geuenich, Michael, Malik, Ahmad, Weber, Ramona, Woo, Tristan, Zhang, Amy, Jang, Gun Ho, Dervovic, Dzana, Al-Zahrani, Khalid N., Tsai, Ricky, Fodil, Nassima, Gros, Philippe, Gallinger, Steven, Neely, G. Gregory, Notta, Faiyaz, Sendoel, Ataman, Campbell, Kieran, Elling, Ulrich, Schramek, Daniel

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Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer von Gendoo, Deena M A, Denroche, Robert E, Zhang, Amy, Radulovich, Nikolina, Jang, Gun Ho, Lemire, Mathieu, Fischer, Sandra, Chadwick, Dianne, Lungu, Ilinca M, Ibrahimov, Emin, Cao, Ping-Jiang, Stein, Lincoln D, Wilson, Julie M, Bartlett, John M S, Tsao, Ming-Sound, Dhani, Neesha, Hedley, David, Gallinger, Steven, Haibe-Kains, Benjamin

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Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma von Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.

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Subtype-Discordant Pancreatic Ductal Adenocarcinoma Tumors Show Intermediate Clinical and Molecular Characteristics von Topham, James T., Karasinska, Joanna M., Lee, Michael K. C., Csizmok, Veronika, Williamson, Laura M., Jang, Gun Ho, Denroche, Robert E., Tsang, Erica S., Kalloger, Steve E., Wong, Hui-li, O'Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Notta, Faiyaz, Loree, Jonathan M., Wilson, Julie M., Bathe, Oliver, Tang, Patricia A., Goodwin, Rachel, Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Renouf, Daniel J., Schaeffer, David F.

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Mitochondrial fitness and cancer risk von Andrew V Kossenkov, Andrew Milcarek, Faiyaz Notta, Gun-Ho Jang, Julie M Wilson, Steven Gallinger, Daniel Cui Zhou, Li Ding, Jagadish C Ghosh, Michela Perego, Annamaria Morotti, Marco Locatelli, Marie E Robert, Valentina Vaira, Dario C Altieri

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