Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells von MAZUMDAR, Tapati, DEVECCHIO, Jennifer, AGYEMAN, Akwasi, TING SHI, HOUGHTON, Janet A

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Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding von Agyeman, Akwasi, Jha, Babal K, Mazumdar, Tapati, Houghton, Janet A

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Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells von MAZUMDAR, Tapati, DEVECCHIO, Jennifer, TING SHI, JONES, Janay, AGYEMAN, Akwasi, HOUGHTON, Janet A

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Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance von Carew, Jennifer S., Nawrocki, Steffan T., Kahue, Charissa N., Zhang, Hui, Yang, Chunying, Chung, Linda, Houghton, Janet A., Huang, Peng, Giles, Francis J., Cleveland, John L.

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Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells von Mazumdar, Tapati, Sandhu, Ranjodh, Qadan, Maha, DeVecchio, Jennifer, Magloire, Victoria, Agyeman, Akwasi, Li, Bibo, Houghton, Janet A

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cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells von Shi, Ting, Mazumdar, Tapati, Devecchio, Jennifer, Duan, Zhong-Hui, Agyeman, Akwasi, Aziz, Mohammad, Houghton, Janet A

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The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer von Mazumdar, Tapati, DeVecchio, Jennifer, Agyeman, Akwasi, Shi, Ting, Houghton, Janet A

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Inhibition of NF-κB Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing... von Jani, Tanvi S., DeVecchio, Jennifer, Mazumdar, Tapati, Agyeman, Akwasi, Houghton, Janet A.

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An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737 von Al-harbi, Sayer, Hill, Brian T., Mazumder, Suparna, Singh, Kamini, DeVecchio, Jennifer, Choudhary, Gaurav, Rybicki, Lisa A., Kalaycio, Matt, Maciejewski, Jaroslaw P., Houghton, Janet A., Almasan, Alexandru

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Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer von Agyeman, Akwasi, Mazumdar, Tapati, Houghton, Janet A

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Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing von Zhang, Ruowen, Wu, Jiahui, Ferrandon, Sylvain, Glowacki, Katie J, Houghton, Janet A

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Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA von Nawrocki, Steffan T., Carew, Jennifer S., Maclean, Kirsteen H., Courage, James F., Huang, Peng, Houghton, Janet A., Cleveland, John L., Giles, Francis J., McConkey, David J.

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Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex component... von MARTIN, Sophie, PHILLIPS, Darren C, SZEKELY-SZUCS, Kinga, ELGHAZI, Lynda, DESMOTS, Fabienne, HOUGHTON, Janet A

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Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines von IZERADJENE, Kamel, DOUGLAS, Leslie, TILLMAN, David M, DELANEY, Addison B, HOUGHTON, Janet A

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Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines von Izeradjene, Kamel, Douglas, Leslie, Delaney, Addison, Houghton, Janet A

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Sphingosine-induced apoptosis in rhabdomyosarcoma cell lines is dependent on pre-mitochondrial Bax activation and post-mitochondrial caspases von Phillips, Darren C, Martin, Sophie, Doyle, Belinda T, Houghton, Janet A

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Influence of Casein Kinase II in Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Human Rhabdomyosarcoma Cells von IZERADJENE, Kamel, DOUGLAS, Leslie

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ATP modulates PTEN subcellular localization in multiple cancer cell lines von Lobo, Glenn P., Waite, Kristin A., Planchon, Sarah M., Romigh, Todd, Houghton, Janet A., Eng, Charis

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Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein ki... von TILLMAN, David M, IZERADJENE, Kamel, SZUCS, Kinga Szekely, DOUGLAS, Leslie, HOUGHTON, Janet A

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Apoptosis and drug response von Houghton, Janet A

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