STAT3 Role in T-Cell Memory Formation von Kaminskiy, Yaroslav, Melenhorst, Jan Joseph

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Cytopenia and leukocyte recovery shape cytokine fluctuations after myeloablative allogeneic hematopoietic stem cell transplantation von Jan Joseph Melenhorst, Xin Tian, Dihua Xu, Netanya G. Sandler, Philip Scheinberg, Angelique Biancotto, Priscila Scheinberg, John Phil McCoy, Jr, Nancy F. Hensel, Zach McIver, Daniel C Douek, Austin John Barrett

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PD1 Expression in EGFRvIII-Directed CAR T Cell Infusion Product for Glioblastoma Is Associated with Clinical Response von Tang, Oliver Y, Tian, Lifeng, Yoder, Todd, Xu, Rong, Kulikovskaya, Irina, Gupta, Minnal, Melenhorst, Jan Joseph, Lacey, Simon F, O'Rourke, Donald M, Binder, Zev A

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Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma von Durgin, Joseph S., Henderson, Fraser, Nasrallah, MacLean P., Mohan, Suyash, Wang, Sumei, Lacey, Simon F., Melenhorst, Jan Joseph, Desai, Arati S., Lee, John Y. K., Maus, Marcela, June, Carl H., Brem, Steven, O'Connor, Roddy S., Binder, Zev, O'Rourke, Donald M.

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Autologous human preclinical modeling of melanoma interpatient clinical responses to immunotherapeutics von Phoon, Yee Peng, Lopes, Jared E, Pfannenstiel, Lukas W, Marcela Diaz-Montero, Claudia, Tian, Ye F, Ernstoff, Marc S, Funchain, Pauline, Ko, Jennifer S, Winquist, Raymond, Losey, Heather C, Melenhorst, Jan Joseph, Gastman, Brian R

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Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant von McIver, Zachariah, Melenhorst, Jan Joseph, Wu, Colin, Grim, Andrew, Ito, Sawa, Cho, Irene, Hensel, Nancy, Battiwalla, Minoo, Barrett, Austin John

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Abstract 1507: Chimeric antigen receptor T cells carrying IDH1 neomorph increase CD8 positive central memory proportion without interfering with cell growth von Xu, Jie, Kaminskiy, Yaroslav, Melenhorst, Jan Joseph

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Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication von Kloss, Christopher C., Lee, Jihyun, Zhang, Aaron, Chen, Fang, Melenhorst, Jan Joseph, Lacey, Simon F., Maus, Marcela V., Fraietta, Joseph A., Zhao, Yangbing, June, Carl H.

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Adaptable Leukemia Cells Resisting CAR T-cell Attack via B-cell Activation von Zhao, Ziran, Melenhorst, Jan Joseph

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Tumor vaccines and beyond von Melenhorst, Jan Joseph, Barrett, Austin John

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Positively charged patches: tonic for CAR fitness von Khan, Meraj H., Melenhorst, Jan Joseph

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Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia von Fraietta, Joseph A., Beckwith, Kyle A., Patel, Prachi R., Ruella, Marco, Zheng, Zhaohui, Barrett, David M., Lacey, Simon F., Melenhorst, Jan Joseph, McGettigan, Shannon E., Cook, Danielle R., Zhang, Changfeng, Xu, Jun, Do, Priscilla, Hulitt, Jessica, Kudchodkar, Sagar B., Cogdill, Alexandria P., Gill, Saar, Porter, David L., Woyach, Jennifer A., Long, Meixiao, Johnson, Amy J., Maddocks, Kami, Muthusamy, Natarajan, Levine, Bruce L., June, Carl H., Byrd, John C., Maus, Marcela V.

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Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia von Frey, Noelle, Gill, Saar, Hexner, Elizabeth O., Schuster, Stephen, Nasta, Sunita, Loren, Alison, Svoboda, Jakub, Stadtmauer, Edward, Landsburg, Daniel J., Mato, Anthony, Levine, Bruce L., Lacey, Simon F., Melenhorst, Jan Joseph, Veloso, Elizabeth, Gaymon, Avery, Pequignot, Edward, Shan, Xinhe, Hwang, Wei-Ting, June, Carl H., Porter, David L.

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Challenges and opportunities of CAR T-cell therapies for CLL von Zhao, Ziran, Grégoire, Céline, Oliveira, Beatriz, Chung, Kunho, Melenhorst, Jan Joseph

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Advancing CAR T-cell therapies: Preclinical insights and clinical translation for hematological malignancies von Arunachalam, Arun K., Grégoire, Céline, Coutinho de Oliveira, Beatriz, Melenhorst, Jan Joseph

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Chimeric antigen receptor T‐cell therapy for haematological malignancies: Insights from fundamental and translational research to bedside practice von Grégoire, Céline, Coutinho de Oliveira, Beatriz, Caimi, Paolo F., Caers, Jo, Melenhorst, Jan Joseph

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Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer von Tchou, Julia, Zhao, Yangbing, Levine, Bruce L, Zhang, Paul J, Davis, Megan M, Melenhorst, Jan Joseph, Kulikovskaya, Irina, Brennan, Andrea L, Liu, Xiaojun, Lacey, Simon F, Posey, Jr, Avery D, Williams, Austin D, So, Alycia, Conejo-Garcia, Jose R, Plesa, Gabriela, Young, Regina M, McGettigan, Shannon, Campbell, Jean, Pierce, Robert H, Matro, Jennifer M, DeMichele, Angela M, Clark, Amy S, Cooper, Laurence J, Schuchter, Lynn M, Vonderheide, Robert H, June, Carl H

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Ultra-low Dose Interleukin-2 Promotes Immune-modulating Function of Regulatory T Cells and Natural Killer Cells in Healthy Volunteers von Ito, Sawa, Bollard, Catherine M, Carlsten, Mattias, Melenhorst, Jan Joseph, Biancotto, Angélique, Wang, Ena, Chen, Jinguo, Kotliarov, Yuri, Cheung, Foo, Xie, Zhi, Marincola, Francesco, Tanimoto, Kazushi, Battiwalla, Minoo, Olnes, Matthew J, Perl, Shira, Schum, Paula, Hughes, Thomas E, Keyvanfar, Keyvan, Hensel, Nancy, Muranski, Pawel, Young, Neal S, Barrett, A John

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Bone Marrow Mesenchymal Stromal Cells to Treat Tissue Damage in Allogeneic Stem Cell Transplant Recipients: Correlation of Biological Markers with Clinical Responses von Yin, Fang, Battiwalla, Minoo, Ito, Sawa, Feng, Xingmin, Chinian, Fariba, Melenhorst, Jan Joseph, Koklanaris, Eleftheria, Sabatino, Marianna, Stroncek, David, Samsel, Leigh, Klotz, Jeffrey, Hensel, Nancy F., Robey, Pamela G., Barrett, A. John

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Temperature Trajectory Sub-phenotypes and the Immuno-Inflammatory Response in Pediatric Sepsis von Yehya, Nadir, Fitzgerald, Julie C., Hayes, Katie, Zhang, Donglan, Bush, Jenny, Koterba, Natalka, Chen, Fang, Tuluc, Florin, Teachey, David T., Balamuth, Fran, Lacey, Simon F., Melenhorst, Jan Joseph, Weiss, Scott L.

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