Characterization of Porcine Hepatic and Intestinal Drug Metabolizing CYP450: Comparison with Human Orthologues from A Quantitative, Activity and Selectivity Perspective von Schelstraete, Wim, Clerck, Laura De, Govaert, Elisabeth, Millecam, Joske, Devreese, Mathias, Deforce, Dieter, Bocxlaer, Jan Van, Croubels, Siska

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Population pharmacokinetics of lisinopril in hypertensive children and adolescents with normal to mildly reduced kidney function von Sandra, Louis, Degraeuwe, Eva, De Bruyne, Pauline, De Baere, Siegrid, Croubels, Siska, Van Bocxlaer, Jan F. P., Raes, Ann, Vande Walle, Johan, Gasthuys, Elke, Vermeulen, An

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Pharmacodynamic Interaction of Remifentanil and Dexmedetomidine on Depth of Sedation and Tolerance of Laryngoscopy von Weerink, Maud A S, Barends, Clemens R M, Muskiet, Ernesto R R, Reyntjens, Koen M. E M, Knotnerus, Froukje H, Oostra, Martine, van Bocxlaer, Jan F P, Struys, Michel M. R F, Colin, Pieter J

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Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma von De Thaye, Elien, Van de Vijver, Koen, Van der Meulen, Joni, Taminau, Joachim, Wagemans, Glenn, Denys, Hannelore, Van Dorpe, Jo, Berx, Geert, Ceelen, Wim, Van Bocxlaer, Jan, De Wever, Olivier

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Joint GC–MS and LC–MS platforms for comprehensive plant metabolomics: Repeatability and sample pre-treatment von t’Kindt, Ruben, Morreel, Kris, Deforce, Dieter, Boerjan, Wout, Van Bocxlaer, Jan

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An Evaluation of Using Population Pharmacokinetic Models to Estimate Pharmacodynamic Parameters for Propofol and Bispectral Index in Children von COPPENS, Marc J, ELEVELD, Douglas J, PROOST, Johannes H, MARKS, Luc A. M, VAN BOCXLAER, Jan F. P, VEREECKE, Hugo, ABSALOM, Anthony R, STRUYS, Michel M. R. F

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Development and validation of a fast and sensitive UPLC–MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity von De Bock, Lies, Boussery, Koen, Colin, Pieter, De Smet, Julie, T’Jollyn, Huybrecht, Van Bocxlaer, Jan

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Influence of administration rate on propofol plasma : Effect site equilibration von STRUYS, Michel M. R. F, COPPENS, Marc J, DE NEVE, Nikolaas, MORTIER, Eric P, DOUFAS, Anthony G, VAN BOCXIAER, Jan F. P, SHAFER, Steven L

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Pharmacokinetics of fluoroquinolones in critical care patients: A bio-analytical HPLC method for the simultaneous quantification of ofloxacin, ciprofloxacin and moxifloxacin in hum... von De Smet, Julie, Boussery, Koen, Colpaert, Kirsten, De Sutter, Peter, De Paepe, Peter, Decruyenaere, Johan, Van Bocxlaer, Jan

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Pharmacokinetics of two formulations of omeprazole administered through a gastrostomy tube in patients with severe neurodevelopmental problems von Boussery, Koen, De Smet, Julie, De Cock, Pieter, Vande Velde, Saskia, Mehuys, Els, De Paepe, Peter, Remon, Jean Paul, Van Bocxlaer, Jan F. P., Van Winckel, Myriam

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In vitro cytochrome P450 activity: Development and validation of a sensitive high performance liquid chromatography–tandem mass spectrometry method for the quantification of six pr... von De Bock, Lies, Vande Casteele, Sofie R.F., Mulliez, Sylvie M.N., Boussery, Koen, Van Bocxlaer, Jan F.P.

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The use of PBPK modeling across the pediatric age range using propofol as a case von Michelet, Robin, Van Bocxlaer, Jan, Allegaert, Karel, Vermeulen, An

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Model-based analysis of treatment effects of paclitaxel microspheres in a microscopic peritoneal carcinomatosis model in mice von Xie, Feifan, De Clercq, Kaat, Vervaet, Chris, Van Bocxlaer, Jan, Colin, Pieter, Vermeulen, An

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Electrospray ionization mass spectrometry for the hydrolysis complexes of cisplatin: implications for the hydrolysis process of platinum complexes von Feifan, Xie, Pieter, Colin, Jan, Van Bocxlaer

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Unravelling the pharmacokinetics of aflatoxin B1: In vitro determination of Michaelis–Menten constants, intrinsic clearance and the metabolic contribution of CYP1A2 and CYP3A4 in p... von Lootens, Orphélie, De Boevre, Marthe, Gasthuys, Elke, Van Bocxlaer, Jan, Vermeulen, An, De Saeger, Sarah

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Possible Mechanisms of the Interplay between Drugs and Mycotoxins-Is There a Possible Impact? von Lootens, Orphélie, Vermeulen, An, Croubels, Siska, De Saeger, Sarah, Van Bocxlaer, Jan, De Boevre, Marthe

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Degradable Ketal-Based Block Copolymer Nanoparticles for Anticancer Drug Delivery: A Systematic Evaluation von Louage, Benoit, Zhang, Qilu, Vanparijs, Nane, Voorhaar, Lenny, Vande Casteele, Sofie, Shi, Yang, Hennink, Wim E, Van Bocxlaer, Jan, Hoogenboom, Richard, De Geest, Bruno G

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Exploring the Impact of Efavirenz on Aflatoxin B1 Metabolism: Insights from a Physiologically Based Pharmacokinetic Model and a Human Liver Microsome Study von Lootens, Orphélie, De Boevre, Marthe, Gasthuys, Elke, De Saeger, Sarah, Van Bocxlaer, Jan, Vermeulen, An

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Flavonoid Deactivation of Excited State Flavins: Reaction Monitoring by Mass Spectrometry von Huvaere, Kevin, Sinnaeve, Bart, Van Bocxlaer, Jan, Skibsted, Leif H

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Claiming desmopressin therapeutic equivalence in children requires pediatric data: a population PKPD analysis von Michelet, Robin, Dossche, Lien, Van Herzeele, Charlotte, Van Bocxlaer, Jan, Vermeulen, An, Vande Walle, Johan

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