Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases von Zheng, Jie, Haberland, Valeriia, Baird, Denis, Walker, Venexia, Haycock, Philip C., Hurle, Mark R., Gutteridge, Alex, Erola, Pau, Liu, Yi, Luo, Shan, Robinson, Jamie, Richardson, Tom G., Staley, James R., Elsworth, Benjamin, Burgess, Stephen, Sun, Benjamin B., Danesh, John, Runz, Heiko, Maranville, Joseph C., Martin, Hannah M., Yarmolinsky, James, Laurin, Charles, Holmes, Michael V., Liu, Jimmy Z., Estrada, Karol, Santos, Rita, McCarthy, Linda, Waterworth, Dawn, Nelson, Matthew R., Smith, George Davey, Butterworth, Adam S., Hemani, Gibran, Scott, Robert A., Gaunt, Tom R.

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The MR-Base platform supports systematic causal inference across the human phenome von Hemani, Gibran, Zheng, Jie, Elsworth, Benjamin, Wade, Kaitlin H, Haberland, Valeriia, Baird, Denis, Laurin, Charles, Burgess, Stephen, Bowden, Jack, Langdon, Ryan, Tan, Vanessa Y, Yarmolinsky, James, Shihab, Hashem A, Timpson, Nicholas J, Evans, David M, Relton, Caroline, Martin, Richard M, Davey Smith, George, Gaunt, Tom R, Haycock, Philip C

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Effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials von Yarmolinsky, James, Gon, Giorgia, Edwards, Phil

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Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer von Yarmolinsky, James, Bull, Caroline J, Vincent, Emma E, Robinson, Jamie, Walther, Axel, Smith, George Davey, Lewis, Sarah J, Relton, Caroline L, Martin, Richard M

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Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study von Fang, Si, Yarmolinsky, James, Gill, Dipender, Bull, Caroline J, Perks, Claire M, Davey Smith, George, Gaunt, Tom R, Richardson, Tom G

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Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis von Bouras, Emmanouil, Karhunen, Ville, Gill, Dipender, Huang, Jian, Haycock, Philip C, Gunter, Marc J, Johansson, Mattias, Brennan, Paul, Key, Tim, Lewis, Sarah J, Martin, Richard M, Murphy, Neil, Platz, Elizabeth A, Travis, Ruth, Yarmolinsky, James, Zuber, Verena, Martin, Paul, Katsoulis, Michail, Freisling, Heinz, Nøst, Therese Haugdahl, Schulze, Matthias B, Dossus, Laure, Hung, Rayjean J, Amos, Christopher I, Ahola-Olli, Ari, Palaniswamy, Saranya, Männikkö, Minna, Auvinen, Juha, Herzig, Karl-Heinz, Keinänen-Kiukaanniemi, Sirkka, Lehtimäki, Terho, Salomaa, Veikko, Raitakari, Olli, Salmi, Marko, Jalkanen, Sirpa, Jarvelin, Marjo-Riitta, Dehghan, Abbas, Tsilidis, Konstantinos K

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Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis von Yarmolinsky, James, Bonilla, Carolina, Haycock, Philip C, Langdon, Ryan J Q, Lotta, Luca A, Langenberg, Claudia, Relton, Caroline L, Lewis, Sarah J, Evans, David M, Davey Smith, George, Martin, Richard M

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Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis von Yarmolinsky, James, Díez-Obrero, Virginia, Richardson, Tom G, Pigeyre, Marie, Sjaarda, Jennifer, Paré, Guillaume, Walker, Venexia M, Vincent, Emma E, Tan, Vanessa Y, Obón-Santacana, Mireia, Albanes, Demetrius, Hampe, Jochen, Gsur, Andrea, Hampel, Heather, Pai, Rish K, Jenkins, Mark, Gallinger, Steven, Casey, Graham, Zheng, Wei, Amos, Christopher I, Smith, George Davey, Martin, Richard M, Moreno, Victor

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Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression von Mitchell, Ruth E, Hartley, April E, Walker, Venexia M, Gkatzionis, Apostolos, Yarmolinsky, James, Bell, Joshua A, Chong, Amanda H W, Paternoster, Lavinia, Tilling, Kate, Smith, George Davey

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Investigating the association between genetically proxied circulating levels of immune checkpoint proteins and cancer survival: protocol for a Mendelian randomisation analysis von Bate, Tessa, Martin, Richard M, Yarmolinsky, James, Haycock, Philip C

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Plasminogen activator inhibitor-1 and type 2 diabetes: a systematic review and meta-analysis of observational studies von Yarmolinsky, James, Bordin Barbieri, Natália, Weinmann, Tobias, Ziegelmann, Patricia K., Duncan, Bruce B., Schmidt, Maria Inês

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Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis von Yarmolinsky, James, Relton, Caroline L, Lophatananon, Artitaya, Muir, Kenneth, Menon, Usha, Gentry-Maharaj, Aleksandra, Walther, Axel, Zheng, Jie, Fasching, Peter, Zheng, Wei, Yin Ling, Woo, Park, Sue K, Kim, Byoung-Gie, Choi, Ji-Yeob, Park, Boyoung, Davey Smith, George, Martin, Richard M, Lewis, Sarah J

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Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis von Hazelwood, Emma, Sanderson, Eleanor, Tan, Vanessa Y, Ruth, Katherine S, Frayling, Timothy M, Dimou, Niki, Gunter, Marc J, Dossus, Laure, Newton, Claire, Ryan, Neil, Pournaras, Dimitri J, O'Mara, Tracy A, Davey Smith, George, Martin, Richard M, Yarmolinsky, James

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Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers von Smith-Byrne, Karl, Hedman, Åsa, Dimitriou, Marios, Desai, Trishna, Sokolov, Alexandr V., Schioth, Helgi B., Koprulu, Mine, Pietzner, Maik, Langenberg, Claudia, Atkins, Joshua, Penha, Ricardo Cortez, McKay, James, Brennan, Paul, Zhou, Sirui, Richards, Brent J., Yarmolinsky, James, Martin, Richard M., Borlido, Joana, Mu, Xinmeng J., Butterworth, Adam, Shen, Xia, Wilson, Jim, Assimes, Themistocles L., Hung, Rayjean J., Amos, Christopher, Purdue, Mark, Rothman, Nathaniel, Chanock, Stephen, Travis, Ruth C., Johansson, Mattias, Mälarstig, Anders

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Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study von Gormley, Mark, Yarmolinsky, James, Dudding, Tom, Burrows, Kimberley, Martin, Richard M., Thomas, Steven, Tyrrell, Jessica, Brennan, Paul, Pring, Miranda, Boccia, Stefania, Olshan, Andrew F., Diergaarde, Brenda, Hung, Rayjean J., Liu, Geoffrey, Legge, Danny, Tajara, Eloiza H., Severino, Patricia, Lacko, Martin, Ness, Andrew R., Smith, George Davey, Vincent, Emma E., Richmond, Rebecca C.

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Mendelian Randomization and Bayesian Colocalization Analysis Implicate Glycoprotein VI as a Potential Drug Target for Cardioembolic Stroke in South Asian Populations von Wu, Siwei, Meena, Devendra, Yarmolinsky, James, Gill, Dipender, Smith, Alexander, Dib, Marie-Joe, Chauhan, Ganesh, Rohatgi, Anand, Dehghan, Abbas, Tzoulaki, Ioanna

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Investigating the causal effect of previously reported therapeutic agents for colorectal cancer prevention: protocol for a Mendelian randomization analysis von Fryer, Ella, Martin, Richard M, Haycock, Philip, Yarmolinsky, James

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Coffee Consumption, Newly Diagnosed Diabetes, and Other Alterations in Glucose Homeostasis: A Cross-Sectional Analysis of the Longitudinal Study of Adult Health (ELSA-Brasil) von Yarmolinsky, James, Mueller, Noel T, Duncan, Bruce B, Bisi Molina, Maria Del Carmen, Goulart, Alessandra C, Schmidt, Maria Inês

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Genetically proxied impaired GIPR signaling and risk of 6 cancers von Rogers, Miranda, Gill, Dipender, Ahlqvist, Emma, Robinson, Tim, Mariosa, Daniela, Johansson, Mattias, Cortez Cardoso Penha, Ricardo, Dossus, Laure, Gunter, Marc J., Moreno, Victor, Davey Smith, George, Martin, Richard M., Yarmolinsky, James

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Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19 von Rontogianni, Marina O., Gill, Dipender, Bouras, Emmanouil, Asimakopoulos, Alexandros-Georgios, Tzoulaki, Ioanna, Karhunen, Ville, Lehtimäki, Terho, Raitakari, Olli, Wielscher, Matthias, Salomaa, Veikko, Jalkanen, Sirpa, Salmi, Marko, Timonen, Markku, Yarmolinsky, James, Chen, Jing, Tobin, Martin D., Izquierdo, Abril G., Herzig, Karl-Heinz, Ioannides, Anne E., Jarvelin, Marjo-Riitta, Dehghan, Abbas, Tsilidis, Konstantinos K.

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