Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo von M. Bader, Stefanie, Cooney, James P., Bhandari, Reet, Mackiewicz, Liana, Dayton, Merle, Sheerin, Dylan, Georgy, Smitha Rose, Murphy, James M., Davidson, Kathryn C., Allison, Cody C., Pellegrini, Marc, Doerflinger, Marcel

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Programmed cell death: the pathways to severe COVID-19? von Bader, Stefanie M, Cooney, James P, Pellegrini, Marc, Doerflinger, Marcel

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Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 von Wines, Bruce D, Kurtovic, Liriye, Trist, Halina M, Esparon, Sandra, Lopez, Ester, Chappin, Klasina, Chan, Li-Jin, Mordant, Francesca L, Lee, Wen Shi, Gherardin, Nicholas A, Patel, Sheila K, Hartley, Gemma E, Pymm, Phillip, Cooney, James P, Beeson, James G, Godfrey, Dale I, Burrell, Louise M, van Zelm, Menno C, Wheatley, Adam K, Chung, Amy W, Tham, Wai-Hong, Subbarao, Kanta, Kent, Stephen J, Hogarth, P Mark

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Corrigendum: Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 von Wines, Bruce D, Kurtovic, Liriye, Trist, Halina M, Esparon, Sandra, Lopez, Ester, Chappin, Klasina, Chan, Li-Jin, Mordant, Francesca L, Lee, Wen Shi, Gherardin, Nicholas A, Patel, Sheila K, Hartley, Gemma E, Pymm, Phillip, Cooney, James P, Beeson, James G, Godfrey, Dale I, Burrell, Louise M, van Zelm, Menno C, Wheatley, Adam K, Chung, Amy W, Tham, Wai-Hong, Subbarao, Kanta, Kent, Stephen J, Hogarth, P Mark

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Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 von Klemm, Theresa, Ebert, Gregor, Calleja, Dale J, Allison, Cody C, Richardson, Lachlan W, Bernardini, Jonathan P, Lu, Bernadine GC, Kuchel, Nathan W, Grohmann, Christoph, Shibata, Yuri, Gan, Zhong Yan, Cooney, James P, Doerflinger, Marcel, Au, Amanda E, Blackmore, Timothy R, van der Heden van Noort, Gerbrand J, Geurink, Paul P, Ovaa, Huib, Newman, Janet, Riboldi‐Tunnicliffe, Alan, Czabotar, Peter E, Mitchell, Jeffrey P, Feltham, Rebecca, Lechtenberg, Bernhard C, Lowes, Kym N, Dewson, Grant, Pellegrini, Marc, Lessene, Guillaume, Komander, David

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Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors von Calleja, Dale J, Kuchel, Nathan, Lu, Bernadine G C, Birkinshaw, Richard W, Klemm, Theresa, Doerflinger, Marcel, Cooney, James P, Mackiewicz, Liana, Au, Amanda E, Yap, Yu Q, Blackmore, Timothy R, Katneni, Kasiram, Crighton, Elly, Newman, Janet, Jarman, Kate E, Call, Melissa J, Lechtenberg, Bernhard C, Czabotar, Peter E, Pellegrini, Marc, Charman, Susan A, Lowes, Kym N, Mitchell, Jeffrey P, Nachbur, Ueli, Lessene, Guillaume, Komander, David

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Mining within the context of a “preferential option for the poor” von Cooney, James P.

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Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway von Simpson, Daniel S., Pang, Jiyi, Weir, Ashley, Kong, Isabella Y., Fritsch, Melanie, Rashidi, Maryam, Cooney, James P., Davidson, Kathryn C., Speir, Mary, Djajawi, Tirta M., Hughes, Sebastian, Mackiewicz, Liana, Dayton, Merle, Anderton, Holly, Doerflinger, Marcel, Deng, Yexuan, Huang, Allan Shuai, Conos, Stephanie A., Tye, Hazel, Chow, Seong H., Rahman, Arfatur, Norton, Raymond S., Naderer, Thomas, Nicholson, Sandra E., Burgio, Gaetan, Man, Si Ming, Groom, Joanna R., Herold, Marco J., Hawkins, Edwin D., Lawlor, Kate E., Strasser, Andreas, Silke, John, Pellegrini, Marc, Kashkar, Hamid, Feltham, Rebecca, Vince, James E.

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Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies von Preston, Simon P., Stutz, Michael D., Allison, Cody C., Nachbur, Ueli, Gouil, Quentin, Tran, Bang Manh, Duvivier, Valerie, Arandjelovic, Philip, Cooney, James P., Mackiewicz, Liana, Meng, Yanxiang, Schaefer, Jan, Bader, Stefanie M., Peng, Hongke, Valaydon, Zina, Rajasekaran, Pravin, Jennison, Charlie, Lopaticki, Sash, Farrell, Ann, Ryan, Marno, Howell, Jess, Croagh, Catherine, Karunakaran, Denuja, Schuster-Klein, Carole, Murphy, James M., Fifis, Theodora, Christophi, Christopher, Vincan, Elizabeth, Blewitt, Marnie E., Thompson, Alexander, Boddey, Justin A., Doerflinger, Marcel, Pellegrini, Marc

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Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice von Pymm, Phillip, Adair, Amy, Chan, Li-Jin, Cooney, James P., Mordant, Francesca L., Allison, Cody C., Lopez, Ester, Haycroft, Ebene R., O’Neill, Matthew T., Tan, Li Lynn, Dietrich, Melanie H., Drew, Damien, Doerflinger, Marcel, Dengler, Michael A., Scott, Nichollas E., Wheatley, Adam K., Gherardin, Nicholas A., Venugopal, Hariprasad, Cromer, Deborah, Davenport, Miles P., Pickering, Raelene, Godfrey, Dale I., Purcell, Damian F. J., Kent, Stephen J., Chung, Amy W., Subbarao, Kanta, Pellegrini, Marc, Glukhova, Alisa, Tham, Wai-Hong

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Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2 von Pymm, Phillip, Redmond, Samuel J., Dolezal, Olan, Mordant, Francesca, Lopez, Ester, Cooney, James P., Davidson, Kathryn C., Haycroft, Ebene R., Tan, Chee Wah, Seneviratna, Rebecca, Grimley, Samantha L., Purcell, Damian F.J., Kent, Stephen J., Wheatley, Adam K., Wang, Lin-Fa, Leis, Andrew, Glukhova, Alisa, Pellegrini, Marc, Chung, Amy W., Subbarao, Kanta, Uldrich, Adam P., Tham, Wai-Hong, Godfrey, Dale I., Gherardin, Nicholas A.

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SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates von Bader, Stefanie M, Cooney, James P, Sheerin, Dylan, Taiaroa, George, Harty, Leigh, Davidson, Kathryn C, Mackiewicz, Liana, Dayton, Merle, Wilcox, Stephen, Whitehead, Lachlan, Rogers, Kelly L, Georgy, Smitha Rose, Coussens, Anna K, Grimley, Samantha L, Corbin, Vincent, Pitt, Miranda, Coin, Lachlan, Pickering, Raelene, Thomas, Merlin, Allison, Cody C, McAuley, Julie, Purcell, Damian F J, Doerflinger, Marcel, Pellegrini, Marc

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Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain von Wheatley, Adam K., Pymm, Phillip, Esterbauer, Robyn, Dietrich, Melanie H., Lee, Wen Shi, Drew, Damien, Kelly, Hannah G., Chan, Li-Jin, Mordant, Francesca L., Black, Katrina A., Adair, Amy, Tan, Hyon-Xhi, Juno, Jennifer A., Wragg, Kathleen M., Amarasena, Thakshila, Lopez, Ester, Selva, Kevin J., Haycroft, Ebene R., Cooney, James P., Venugopal, Hariprasad, Tan, Li Lynn, O Neill, Matthew T., Allison, Cody C., Cromer, Deborah, Davenport, Miles P., Bowen, Richard A., Chung, Amy W., Pellegrini, Marc, Liddament, Mark T., Glukhova, Alisa, Subbarao, Kanta, Kent, Stephen J., Tham, Wai-Hong

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Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice von Arandjelovic, Philip, Kim, Youry, Cooney, James P, Preston, Simon P, Doerflinger, Marcel, McMahon, James H, Garner, Sarah E, Zerbato, Jennifer M, Roche, Michael, Tumpach, Carolin, Ong, Jesslyn, Sheerin, Dylan, Smyth, Gordon K, Anderson, Jenny L, Allison, Cody C, Lewin, Sharon R, Pellegrini, Marc

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Rapid detection of monkeypox virus using a CRISPR-Cas12a mediated assay: a laboratory validation and evaluation study von Low, Soo Jen, O'Neill, Matthew T, Kerry, William J, Krysiak, Marcelina, Papadakis, Georgina, Whitehead, Lachlan W, Savic, Ivana, Prestedge, Jacqueline, Williams, Lewis, Cooney, James P, Tran, Thomas, Lim, Chuan K, Caly, Leon, Towns, Janet M, Bradshaw, Catriona S, Fairley, Christopher, Chow, Eric P F, Chen, Marcus Y, Pellegrini, Marc, Pasricha, Shivani, Williamson, Deborah A

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mRNA vaccines encoding membrane-anchored RBDs of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting von Al-Wassiti, Hareth A., Fabb, Stewart A., Grimley, Samantha L., Kochappan, Ruby, Ho, Joan K., Wong, Chinn Yi, Tan, Chee Wah, Payne, Thomas J., Takanashi, Asuka, Lee, Chee Leng, Mugan, Rekha Shandre, Sicilia, Horatio, Teo, Serena L.Y., McAuley, Julie, Ellenberg, Paula, Cooney, James P., Davidson, Kathryn C., Bowen, Richard, Pellegrini, Marc, Rockman, Steven, Godfrey, Dale I., Nolan, Terry M., Wang, Lin-fa, Deliyannis, Georgia, Purcell, Damian F.J., Pouton, Colin W.

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Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine von Deliyannis, Georgia, Gherardin, Nicholas A., Wong, Chinn Yi, Grimley, Samantha L., Cooney, James P., Redmond, Samuel J., Ellenberg, Paula, Davidson, Kathryn C., Mordant, Francesca L., Smith, Tim, Gillard, Marianne, Lopez, Ester, McAuley, Julie, Tan, Chee Wah, Wang, Jing J., Zeng, Weiguang, Littlejohn, Mason, Zhou, Runhong, Fuk-Woo Chan, Jasper, Chen, Zhi-wei, Hartwig, Airn E., Bowen, Richard, Mackenzie, Jason M., Vincan, Elizabeth, Torresi, Joseph, Kedzierska, Katherine, Pouton, Colin W., Gordon, Tom P., Wang, Lin-fa, Kent, Stephen J., Wheatley, Adam K., Lewin, Sharon R., Subbarao, Kanta, Chung, Amy W., Pellegrini, Marc, Munro, Trent, Nolan, Terry, Rockman, Steven, Jackson, David C., Purcell, Damian F.J., Godfrey, Dale I.

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Human Nasal Epithelium Organoids for Assessing Neutralizing Antibodies to a Protective SARS-CoV-2 Virus-like Particle Vaccine von Carrera Montoya, Julio, Collett, Simon, Fernandez Ruiz, Daniel, Earnest, Linda, Edeling, Melissa A., Yap, Ashley Huey Yiing, Wong, Chinn Yi, Cooney, James P., Davidson, Kathryn C., Roberts, Jason, Rockman, Steven, Tran, Bang M., McAuley, Julie L., Deliyannis, Georgia, Grimley, Samantha L., Purcell, Damian F. J., Waters, Shafagh A., Godfrey, Dale I., Hans, Dhiraj, Pellegrini, Marc, Mackenzie, Jason M., Vincan, Elizabeth, Heath, William R., Torresi, Joseph

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ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system von Lin, Amy E, Ebert, Gregor, Ow, Yongkai, Preston, Simon P, Toe, Jesse G, Cooney, James P, Scott, Hamish W, Sasaki, Masato, Saibil, Samuel D, Dissanayake, Dilan, Kim, Raymond H, Wakeham, Andrew, You-Ten, Annick, Shahinian, Arda, Duncan, Gordon, Silvester, Jennifer, Ohashi, Pamela S, Mak, Tak W, Pellegrini, Marc

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Hospital Executive Leadership: A Critical Component for Improving Care at the End of Life von Cooney, James P., Landers, Glenn M., Williams, Julianna M.

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