Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma von Flaherty, Keith T, Robert, Caroline, Hersey, Peter, Nathan, Paul, Garbe, Claus, Milhem, Mohammed, Demidov, Lev V, Hassel, Jessica C, Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M.G, Utikal, Jochen, Dreno, Brigitte, Nyakas, Marta, Middleton, Mark R, Becker, Jürgen C, Casey, Michelle, Sherman, Laurie J, Wu, Frank S, Ouellet, Daniele, Martin, Anne-Marie, Patel, Kiran, Schadendorf, Dirk

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Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study von Robert, Caroline, Prof, Ribas, Antoni, Prof, Schachter, Jacob, Prof, Arance, Ana, MD, Grob, Jean-Jacques, Prof, Mortier, Laurent, Prof, Daud, Adil, Prof, Carlino, Matteo S, MB, McNeil, Catriona M, MD, Lotem, Michal, Prof, Larkin, James M G, Prof, Lorigan, Paul, Prof, Neyns, Bart, Prof, Blank, Christian U, Prof, Petrella, Teresa M, MD, Hamid, Omid, MD, Su, Shu-Chih, PhD, Krepler, Clemens, MD, Ibrahim, Nageatte, MD, Long, Georgina V, Prof

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Active surveillance in metastatic renal-cell carcinoma: a prospective, phase 2 trial von Rini, Brian I, Prof, Dorff, Tanya B, MD, Elson, Paul, ScD, Rodriguez, Cristina Suarez, MD, Shepard, Dale, MD, Wood, Laura, MSN, Humbert, Jordi, BSc, Pyle, Linda, RN, Wong, Yu-Ning, MD, Finke, James H, Prof, Rayman, Patricia A, MS, Larkin, James M G, FRCP, Garcia, Jorge A, MD, Plimack, Elizabeth R, MD

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Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind st... von Long, Georgina V, Prof, Dummer, Reinhard, Prof, Hamid, Omid, MD, Gajewski, Thomas F, Prof, Caglevic, Christian, MD, Dalle, Stephane, Prof, Arance, Ana, MD, Carlino, Matteo S, PhD, Grob, Jean-Jacques, Prof, Kim, Tae Min, Prof, Demidov, Lev, Prof, Robert, Caroline, Prof, Larkin, James, Prof, Anderson, James R, PhD, Maleski, Janet, BSN, Jones, Mark, MD, Diede, Scott J, MD, Mitchell, Tara C, MD

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Open-Label, Single-Arm Phase II Study of Pembrolizumab Monotherapy as First-Line Therapy in Patients With Advanced Clear Cell Renal Cell Carcinoma von McDermott, David F, Lee, Jae-Lyun, Bjarnason, Georg A, Larkin, James M G, Gafanov, Rustem A, Kochenderfer, Mark D, Jensen, Niels Viggo, Donskov, Frede, Malik, Jahangeer, Poprach, Alexandr, Tykodi, Scott S, Alonso-Gordoa, Teresa, Cho, Daniel C, Geertsen, Poul F, Climent Duran, Miguel Angel, DiSimone, Christopher, Silverman, Rachel Kloss, Perini, Rodolfo F, Schloss, Charles, Atkins, Michael B

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Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma von Sarnaik, Amod A, Hamid, Omid, Khushalani, Nikhil I, Lewis, Karl D, Medina, Theresa, Kluger, Harriet M, Thomas, Sajeve S, Domingo-Musibay, Evidio, Pavlick, Anna C, Whitman, Eric D, Martin-Algarra, Salvador, Corrie, Pippa, Curti, Brendan D, Oláh, Judit, Lutzky, Jose, Weber, Jeffrey S, Larkin, James M G, Shi, Wen, Takamura, Toshimi, Jagasia, Madan, Qin, Harry, Wu, Xiao, Chartier, Cecile, Graf Finckenstein, Friedrich, Fardis, Maria, Kirkwood, John M, Chesney, Jason A

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Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma von Kelderman, Sander, Heemskerk, Bianca, van Tinteren, Harm, van den Brom, Rob R. H., Hospers, Geke A. P., van den Eertwegh, Alfonsus J. M., Kapiteijn, Ellen W., de Groot, Jan Willem B., Soetekouw, Patricia, Jansen, Rob L., Fiets, Edward, Furness, Andrew J. S., Renn, Alexandra, Krzystanek, Marcin, Szallasi, Zoltan, Lorigan, Paul, Gore, Martin E., Schumacher, Ton N. M., Haanen, John B. A. G., Larkin, James M. G., Blank, Christian U.

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Translational implications of tumor heterogeneity von Jamal-Hanjani, Mariam, Quezada, Sergio A, Larkin, James, Swanton, Charles

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Galactic-scale Feedback Observed in the 3C 298 Quasar Host Galaxy von Vayner, Andrey, Wright, Shelley A., Murray, Norman, Armus, Lee, Larkin, James E., Mieda, Etsuko

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Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study von Serra-Bellver, Patricio, Versluis, Judith M., Oberoi, Honey K., Zhou, Cong, Slattery, Timothy D., Khan, Yasir, Patrinely, James R., Pires da Silva, Inês, Martínez-Vila, C., Cook, Natalie, Graham, Donna M., Carlino, Matteo S., Menzies, Alexander M., Arance, Ana M., Johnson, Douglas B., Long, Georgina V., Pickering, Lisa, Larkin, James M.G., Blank, Christian U., Lorigan, Paul

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Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia von Pannell, Maria, Economopoulos, Vasiliki, Wilson, Thomas C., Kersemans, Veerle, Isenegger, Patrick G., Larkin, James R., Smart, Sean, Gilchrist, Stuart, Gouverneur, Véronique, Sibson, Nicola R.

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Phase II Study Investigating the Safety and Efficacy of Savolitinib and Durvalumab in Metastatic Papillary Renal Cancer (CALYPSO) von Suárez, Cristina, Larkin, James M G, Patel, Poulam, Valderrama, Begoña P, Rodriguez-Vida, Alejo, Glen, Hilary, Thistlethwaite, Fiona, Ralph, Christy, Srinivasan, Gopalakrishnan, Mendez-Vidal, Maria Jose, Hartmaier, Ryan, Markovets, Aleksandra, Prendergast, Aaron, Szabados, Bernadett, Mousa, Kelly, Powles, Thomas

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Tumor pH and Protein Concentration Contribute to the Signal of Amide Proton Transfer Magnetic Resonance Imaging von Ray, Kevin J, Simard, Manon A, Larkin, James R, Coates, James, Kinchesh, Paul, Smart, Sean C, Higgins, Geoff S, Chappell, Michael A, Sibson, Nicola R

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Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal von Irshad, Zehra, Xue, Mingzhan, Ashour, Amal, Larkin, James R., Thornalley, Paul J., Rabbani, Naila

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Boronic Acid Resin for Selective Immobilization of Canonically Encoded Proteins von Larkin, James O., Jayanthi, Brianna, Segatori, Laura, Ball, Zachary T.

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Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial von Motzer, Robert J., Robbins, Paul B., Powles, Thomas, Albiges, Laurence, Haanen, John B., Larkin, James, Mu, Xinmeng Jasmine, Ching, Keith A., Uemura, Motohide, Pal, Sumanta K., Alekseev, Boris, Gravis, Gwenaelle, Campbell, Matthew T., Penkov, Konstantin, Lee, Jae Lyun, Hariharan, Subramanian, Wang, Xiao, Zhang, Weidong, Wang, Jing, Chudnovsky, Aleksander, di Pietro, Alessandra, Donahue, Amber C., Choueiri, Toni K.

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Dynamical Constraints on the HR 8799 Planets with GPI von Wang, Jason J., Graham, James R., Dawson, Rebekah, Fabrycky, Daniel, De Rosa, Robert J., Pueyo, Laurent, Konopacky, Quinn, Macintosh, Bruce, Marois, Christian, Chiang, Eugene, Ammons, S. Mark, Arriaga, Pauline, Bailey, Vanessa P., Barman, Travis, Bulger, Joanna, Chilcote, Jeffrey, Cotten, Tara, Doyon, Rene, Duchêne, Gaspard, Esposito, Thomas M., Fitzgerald, Michael P., Follette, Katherine B., Gerard, Benjamin L., Goodsell, Stephen J., Greenbaum, Alexandra Z., Hibon, Pascale, Hung, Li-Wei, Ingraham, Patrick, Kalas, Paul, Larkin, James E., Maire, Jérôme, Marchis, Franck, Marley, Mark S., Metchev, Stanimir, Millar-Blanchaer, Maxwell A., Nielsen, Eric L., Oppenheimer, Rebecca, Palmer, David, Patience, Jennifer, Perrin, Marshall, Poyneer, Lisa, Rajan, Abhijith, Rameau, Julien, Rantakyrö, Fredrik T., Ruffio, Jean-Baptiste, Savransky, Dmitry, Schneider, Adam C., Sivaramakrishnan, Anand, Song, Inseok, Soummer, Remi, Thomas, Sandrine, Wallace, J. Kent, Ward-Duong, Kimberly, Wiktorowicz, Sloane, Wolff, Schuyler

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Prevalence and predictors of medication non-adherence among people living with multimorbidity: a systematic review and meta-analysis von Foley, Louise, Larkin, James, Lombard-Vance, Richard, Murphy, Andrew W, Hynes, Lisa, Galvin, Emer, Molloy, Gerard J

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Nivolumab versus everolimus in patients with advanced renal cell carcinoma: Updated results with long‐term follow‐up of the randomized, open‐label, phase 3 CheckMate 025 trial... von Motzer, Robert J., Escudier, Bernard, George, Saby, Hammers, Hans J., Srinivas, Sandhya, Tykodi, Scott S., Sosman, Jeffrey A., Plimack, Elizabeth R., Procopio, Giuseppe, McDermott, David F., Castellano, Daniel, Choueiri, Toni K., Donskov, Frede, Gurney, Howard, Oudard, Stéphane, Richardet, Martin, Peltola, Katriina, Alva, Ajjai S., Carducci, Michael, Wagstaff, John, Chevreau, Christine, Fukasawa, Satoshi, Tomita, Yoshihiko, Gauler, Thomas C., Kollmannsberger, Christian K., Schutz, Fabio A., Larkin, James, Cella, David, McHenry, M. Brent, Saggi, Shruti Shally, Tannir, Nizar M.

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A Spatially Resolved Survey of Distant Quasar Host Galaxies. I. Dynamics of Galactic Outflows von Vayner, Andrey, Wright, Shelley A., Murray, Norman, Armus, Lee, Boehle, Anna, Cosens, Maren, Larkin, James E., Mieda, Etsuko, Walth, Gregory

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