The intersection of cell death and inflammasome activation von Vince, James E., Silke, John

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Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation von Vince, James E., Wong, W. Wei-Lynn, Gentle, Ian, Lawlor, Kate E., Allam, Ramanjaneyulu, O'Reilly, Lorraine, Mason, Kylie, Gross, Olaf, Ma, Stephen, Guarda, Greta, Anderton, Holly, Castillo, Rosa, Häcker, Georg, Silke, John, Tschopp, Jürg

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Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner von Conos, Stephanie A., Chen, Kaiwen W., De Nardo, Dominic, Hara, Hideki, Whitehead, Lachlan, Núñez, Gabriel, Masters, Seth L., Murphy, James M., Schroder, Kate, Vaux, David L., Lawlor, Kate E., Lindqvist, Lisa M., Vince, James E.

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RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis von Rickard, James A., O’Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby J., Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti, Silke, John

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Activated MLKL attenuates autophagy following its translocation to intracellular membranes von Frank, Daniel, Vaux, David L., Murphy, James M., Vince, James E., Lindqvist, Lisa M.

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The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation von Vijayaraj, Swarna L., Feltham, Rebecca, Rashidi, Maryam, Frank, Daniel, Liu, Zhengyang, Simpson, Daniel S., Ebert, Gregor, Vince, Angelina, Herold, Marco J., Kueh, Andrew, Pearson, Jaclyn S., Dagley, Laura F., Murphy, James M., Webb, Andrew I., Lawlor, Kate E., Vince, James E.

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Pyroptosis versus necroptosis: similarities, differences, and crosstalk von Frank, Daniel, Vince, James E.

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Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8 von Sagulenko, Vitaliya, Vitak, Nazarii, Vajjhala, Parimala R., Vince, James E., Stacey, Katryn J.

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL von Lawlor, Kate E., Khan, Nufail, Mildenhall, Alison, Gerlic, Motti, Croker, Ben A., D’Cruz, Akshay A., Hall, Cathrine, Kaur Spall, Sukhdeep, Anderton, Holly, Masters, Seth L., Rashidi, Maryam, Wicks, Ian P., Alexander, Warren S., Mitsuuchi, Yasuhiro, Benetatos, Christopher A., Condon, Stephen M., Wong, W. Wei-Lynn, Silke, John, Vaux, David L., Vince, James E.

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Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model von Erlich, Ziv, Shlomovitz, Inbar, Edry-Botzer, Liat, Cohen, Hadar, Frank, Daniel, Wang, Hanqing, Lew, Andrew M., Lawlor, Kate E., Zhan, Yifan, Vince, James E., Gerlic, Motti

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Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications von Sharma, Arpeeta, Tate, Mitchel, Mathew, Geetha, Vince, James E, Ritchie, Rebecca H, de Haan, Judy B

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cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner von Wong, W. Wei-Lynn, Vince, James E., Lalaoui, Najoua, Lawlor, Kate E., Chau, Diep, Bankovacki, Aleksandra, Anderton, Holly, Metcalf, Donald, O'Reilly, Lorraine, Jost, Philipp J., Murphy, James M., Alexander, Warren S., Strasser, Andreas, Vaux, David L., Silke, John

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Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma von Best, Sarah A., Ding, Sheryl, Kersbergen, Ariena, Dong, Xueyi, Song, Ji-Ying, Xie, Yi, Reljic, Boris, Li, Kaiming, Vince, James E., Rathi, Vivek, Wright, Gavin M., Ritchie, Matthew E., Sutherland, Kate D.

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More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling von Khan, Nufail, Lawlor, Kate E, Murphy, James M, Vince, James E

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XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation von Lawlor, Kate E., Feltham, Rebecca, Yabal, Monica, Conos, Stephanie A., Chen, Kaiwen W., Ziehe, Stephanie, Graß, Carina, Zhan, Yifan, Nguyen, Tan A., Hall, Cathrine, Vince, Angelina J., Chatfield, Simon M., D’Silva, Damian B., Pang, Kenneth C., Schroder, Kate, Silke, John, Vaux, David L., Jost, Philipp J., Vince, James E.

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Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming von Allam, Ramanjaneyulu, Lawlor, Kate E, Yu, Eric Chi-Wang, Mildenhall, Alison L, Moujalled, Donia M, Lewis, Rowena S, Ke, Francine, Mason, Kylie D, White, Michael J, Stacey, Katryn J, Strasser, Andreas, O'Reilly, Lorraine A, Alexander, Warren, Kile, Benjamin T, Vaux, David L, Vince, James E

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The pathogen Candida albicans hijacks pyroptosis for escape from macrophages von Uwamahoro, Nathalie, Verma-Gaur, Jiyoti, Shen, Hsin-Hui, Qu, Yue, Lewis, Rowena, Lu, Jingxiong, Bambery, Keith, Masters, Seth L, Vince, James E, Naderer, Thomas, Traven, Ana

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IFNγ: Priming for death von Vince, James E

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Oxidative photocatalysis on membranes triggers non-canonical pyroptosis von Lee, Chaiheon, Park, Mingyu, Wijesinghe, W. C. Bhashini, Na, Seungjin, Lee, Chae Gyu, Hwang, Eunhye, Yoon, Gwangsu, Lee, Jeong Kyeong, Roh, Deok-Ho, Kwon, Yoon Hee, Yang, Jihyeon, Hughes, Sebastian A., Vince, James E., Seo, Jeong Kon, Min, Duyoung, Kwon, Tae-Hyuk

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The role of caspase-8 in inflammatory signalling and pyroptotic cell death von Pang, Jiyi, Vince, James E

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