Advances and Challenges of HDAC Inhibitors in Cancer Therapeutics von McClure, Jesse J, Li, Xiaoyang, Chou, C James

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Comparison of three zinc binding groups for HDAC inhibitors – A potency, selectivity and enzymatic kinetics study von Yue, Kairui, Qin, Mengting, Huang, Chao, James Chou, C., Jiang, Yuqi, Li, Xiaoyang

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Silver-Catalyzed Direct Thiolation of Quinones by Activation of Aryl Disulfides to Synthesize Quinonyl Aryl Thioethers von Zhang, Cheng, McClure, Jesse, Chou, C. James

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Extracellular vesicle-mediated long-range communication in stressed retinal pigment epithelial cell monolayers von Shah, Navjot, Ishii, Masakii, Brandon, Carlene, Ablonczy, Zsolt, Cai, Jingwen, Liu, Yutao, Chou, C. James, Rohrer, Bärbel

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Development of peptide-functionalized synthetic hydrogel microarrays for stem cell and tissue engineering applications von Jia, Jia, Coyle, Robert C., Richards, Dylan J., Berry, Christopher Lloyd, Barrs, Ryan Walker, Biggs, Joshua, James Chou, C., Trusk, Thomas C., Mei, Ying

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Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model von Rai, Myriam, Soragni, Elisabetta, Chou, C James, Barnes, Glenn, Jones, Steve, Rusche, James R, Gottesfeld, Joel M, Pandolfo, Massimo

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Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia von McClure, Jesse J, Zhang, Cheng, Inks, Elizabeth S, Peterson, Yuri K, Li, Jiaying, Chou, C. James

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Short Laminin Peptide for Improved Neural Stem Cell Growth von Li, Xiaowei, Liu, Xiaoyan, Josey, Benjamin, Chou, C. James, Tan, Yu, Zhang, Ning, Wen, Xuejun

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Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies von Liang, Xuewu, Zang, Jie, Li, Xiaoyang, Tang, Shuai, Huang, Min, Geng, Meiyu, Chou, C. James, Li, Chunpu, Cao, Yichun, Xu, Wenfang, Liu, Hong, Zhang, Yingjie

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Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects In Vitro and Neuroprotective Effects in a Pharmacological Alzheimer’s Disea... von He, Feng, Chou, C. James, Scheiner, Matthias, Poeta, Eleonora, Yuan Chen, Natalia, Gunesch, Sandra, Hoffmann, Matthias, Sotriffer, Christoph, Monti, Barbara, Maurice, Tangui, Decker, Michael

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Histone Deacetylase Inhibition by Gut Microbe-Generated Short-Chain Fatty Acids Entrains Intestinal Epithelial Circadian Rhythms von Fawad, Jibraan A., Luzader, Deborah H., Hanson, Gabriel F., Moutinho, Thomas J., McKinney, Craig A., Mitchell, Paul G., Brown-Steinke, Kathleen, Kumar, Ajay, Park, Miri, Lee, Suengwon, Bolick, David T., Medlock, Greg L., Zhao, Jesse Y., Rosselot, Andrew E., Chou, C. James, Eshleman, Emily M., Alenghat, Theresa, Hong, Christian I., Papin, Jason A., Moore, Sean R.

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Pimelic Diphenylamide 106 Is a Slow, Tight-binding Inhibitor of Class I Histone Deacetylases von Chou, C. James, Herman, David, Gottesfeld, Joel M.

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Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer’s disease: Design, synthesis, and biological evaluation von Xu, Ana, He, Feng, Zhang, Xiangna, Li, Xiaoyang, Ran, Yingying, Wei, Chao, James Chou, C., Zhang, Rui, Wu, Jingde

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Development of selective HDAC6 inhibitors with in vitro and in vivo anti-multiple myeloma activity von Li, Shunda, Zhao, Chunlong, Zhang, Guozhen, Xu, Qifu, Liu, Qian, Zhao, Wei, James Chou, C., Zhang, Yingjie

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Development of a Bestatin-SAHA Hybrid with Dual Inhibitory Activity against APN and HDAC von Cao, Jiangying, Zhao, Wei, Zhao, Chunlong, Liu, Qian, Li, Shunda, Zhang, Guozhen, Chou, C James, Zhang, Yingjie

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Structure–Activity Relationship Study of Vitamin K Derivatives Yields Highly Potent Neuroprotective Agents von Josey, Benjamin J, Inks, Elizabeth S, Wen, Xuejun, Chou, C. James

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LP340, a novel histone deacetylase inhibitor, decreases liver injury and fibrosis in mice: role of oxidative stress and microRNA-23a von Samuvel, Devadoss J, Lemasters, John J, Chou, C James, Zhong, Zhi

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Design, synthesis and anti-tumor activity study of novel histone deacetylase inhibitors containing isatin-based caps and o-phenylenediamine-based zinc binding groups von Gao, Shuai, Zang, Jie, Gao, Qianwen, Liang, Xuewu, Ding, Qinge, Li, Xiaoyang, Xu, Wenfang, Chou, C. James, Zhang, Yingjie

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Randomized, Placebo-Controlled Trial of Olanzapine as Maintenance Therapy in Patients With Bipolar I Disorder Responding to Acute Treatment With Olanzapine von Tohen, Mauricio, Calabrese, Joseph R., Sachs, Gary S., Banov, Michael D., Detke, Holland C., Risser, Richard, Baker, Robert W., Chou, James C.-Y., Bowden, Charles L.

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Targeted multiplex validation of CSF proteomic biomarkers: implications for differentiation of PCNSL from tumor-free controls and other brain tumors von Ma, Jingjing, Lin, Zhiguang, Zhang, Yaqi, Ding, Yun, Tang, Qiming, Qian, Yufeng, Jin, Bo, Luo, Ruben Y, Liao, Wei-Li, Thyparambil, Sheeno, Han, Zhi, Chou, C James, Schilling, James, Li, Qing, Zhang, Mengxue, Lin, Yunan, Ma, Yan, Sylvester, Karl G, Nagpal, Seema, McElhinney, Doff B, Ling, Xuefeng B, Chen, Bobin

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