Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma von Chen, Xiang, Bahrami, Armita, Pappo, Alberto, Easton, John, Dalton, James, Hedlund, Erin, Ellison, David, Shurtleff, Sheila, Wu, Gang, Wei, Lei, Parker, Matthew, Rusch, Michael, Nagahawatte, Panduka, Wu, Jianrong, Mao, Shenghua, Boggs, Kristy, Mulder, Heather, Yergeau, Donald, Lu, Charles, Ding, Li, Edmonson, Michael, Qu, Chunxu, Wang, Jianmin, Li, Yongjin, Navid, Fariba, Daw, Najat C, Mardis, Elaine R, Wilson, Richard K, Downing, James R, Zhang, Jinghui, Dyer, Michael A

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The biology of pediatric acute megakaryoblastic leukemia von Gruber, Tanja A., Downing, James R.

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Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis von Levine, Jacob H., Simonds, Erin F., Bendall, Sean C., Davis, Kara L., Amir, El-ad D., Tadmor, Michelle D., Litvin, Oren, Fienberg, Harris G., Jager, Astraea, Zunder, Eli R., Finck, Rachel, Gedman, Amanda L., Radtke, Ina, Downing, James R., Pe’er, Dana, Nolan, Garry P.

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Exploring genomic alteration in pediatric cancer using ProteinPaint von Zhou, Xin, Edmonson, Michael N, Wilkinson, Mark R, Patel, Aman, Wu, Gang, Liu, Yu, Li, Yongjin, Zhang, Zhaojie, Rusch, Michael C, Parker, Matthew, Becksfort, Jared, Downing, James R, Zhang, Jinghui

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Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration von Pui, Ching-Hon, Yang, Jun J, Hunger, Stephen P, Pieters, Rob, Schrappe, Martin, Biondi, Andrea, Vora, Ajay, Baruchel, André, Silverman, Lewis B, Schmiegelow, Kjeld, Escherich, Gabriele, Horibe, Keizo, Benoit, Yves C M, Izraeli, Shai, Yeoh, Allen Eng Juh, Liang, Der-Cherng, Downing, James R, Evans, William E, Relling, Mary V, Mullighan, Charles G

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Improved CNS Control of Childhood Acute Lymphoblastic Leukemia Without Cranial Irradiation: St Jude Total Therapy Study 16 von Jeha, Sima, Pei, Deqing, Choi, John, Cheng, Cheng, Sandlund, John T, Coustan-Smith, Elaine, Campana, Dario, Inaba, Hiroto, Rubnitz, Jeffrey E, Ribeiro, Raul C, Gruber, Tanja A, Raimondi, Susana C, Khan, Raja B, Yang, Jun J, Mullighan, Charles G, Downing, James R, Evans, William E, Relling, Mary V, Pui, Ching-Hon

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Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome von Rusch, Michael, Nakitandwe, Joy, Shurtleff, Sheila, Newman, Scott, Zhang, Zhaojie, Edmonson, Michael N., Parker, Matthew, Jiao, Yuannian, Ma, Xiaotu, Liu, Yanling, Gu, Jiali, Walsh, Michael F., Becksfort, Jared, Thrasher, Andrew, Li, Yongjin, McMurry, James, Hedlund, Erin, Patel, Aman, Easton, John, Yergeau, Donald, Vadodaria, Bhavin, Tatevossian, Ruth G., Raimondi, Susana, Hedges, Dale, Chen, Xiang, Hagiwara, Kohei, McGee, Rose, Robinson, Giles W., Klco, Jeffery M., Gruber, Tanja A., Ellison, David W., Downing, James R, Zhang, Jinghui

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Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia von Topka, Sabine, Vijai, Joseph, Walsh, Michael F, Jacobs, Lauren, Maria, Ann, Villano, Danylo, Gaddam, Pragna, Wu, Gang, McGee, Rose B, Quinn, Emily, Inaba, Hiroto, Hartford, Christine, Pui, Ching-Hon, Pappo, Alberto, Edmonson, Michael, Zhang, Michael Y, Stepensky, Polina, Steinherz, Peter, Schrader, Kasmintan, Lincoln, Anne, Bussel, James, Lipkin, Steve M, Goldgur, Yehuda, Harit, Mira, Stadler, Zsofia K, Mullighan, Charles, Weintraub, Michael, Shimamura, Akiko, Zhang, Jinghui, Downing, James R, Nichols, Kim E, Offit, Kenneth

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The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis von Aldiri, Issam, Xu, Beisi, Wang, Lu, Chen, Xiang, Hiler, Daniel, Griffiths, Lyra, Valentine, Marc, Shirinifard, Abbas, Thiagarajan, Suresh, Sablauer, Andras, Barabas, Marie-Elizabeth, Zhang, Jiakun, Johnson, Dianna, Frase, Sharon, Zhou, Xin, Easton, John, Zhang, Jinghui, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Dyer, Michael A.

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Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations von Brady, Samuel W., Liu, Yanling, Ma, Xiaotu, Gout, Alexander M., Hagiwara, Kohei, Zhou, Xin, Wang, Jian, Macias, Michael, Chen, Xiaolong, Easton, John, Mulder, Heather L., Rusch, Michael, Wang, Lu, Nakitandwe, Joy, Lei, Shaohua, Davis, Eric M., Naranjo, Arlene, Cheng, Cheng, Maris, John M., Downing, James R., Cheung, Nai-Kong V., Hogarty, Michael D., Dyer, Michael A., Zhang, Jinghui

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CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data von Tian, Liqing, Li, Yongjin, Edmonson, Michael N, Zhou, Xin, Newman, Scott, McLeod, Clay, Thrasher, Andrew, Liu, Yu, Tang, Bo, Rusch, Michael C, Easton, John, Ma, Jing, Davis, Eric, Trull, Austyn, Michael, J Robert, Szlachta, Karol, Mullighan, Charles, Baker, Suzanne J, Downing, James R, Ellison, David W, Zhang, Jinghui

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Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia von Mullighan, Charles G., Phillips, Letha A., Su, Xiaoping, Ma, Jing, Miller, Christopher B., Shurtleff, Sheila A., Downing, James R.

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Structure and evolution of double minutes in diagnosis and relapse brain tumors von Xu, Ke, Ding, Liang, Chang, Ti-Cheng, Shao, Ying, Chiang, Jason, Mulder, Heather, Wang, Shuoguo, Shaw, Tim I., Wen, Ji, Hover, Laura, McLeod, Clay, Wang, Yong-Dong, Easton, John, Rusch, Michael, Dalton, James, Downing, James R., Ellison, David W., Zhang, Jinghui, Baker, Suzanne J., Wu, Gang

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Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation von Pui, Ching-Hon, Campana, Dario, Pei, Deqing, Bowman, W. Paul, Sandlund, John T, Kaste, Sue C, Ribeiro, Raul C, Rubnitz, Jeffrey E, Raimondi, Susana C, Onciu, Mihaela, Coustan-Smith, Elaine, Kun, Larry E, Jeha, Sima, Cheng, Cheng, Howard, Scott C, Simmons, Vickey, Bayles, Amy, Metzger, Monika L, Boyett, James M, Leung, Wing, Handgretinger, Rupert, Downing, James R, Evans, William E, Relling, Mary V

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New markers for minimal residual disease detection in acute lymphoblastic leukemia von Coustan-Smith, Elaine, Song, Guangchun, Clark, Christopher, Key, Laura, Liu, Peixin, Mehrpooya, Mohammad, Stow, Patricia, Su, Xiaoping, Shurtleff, Sheila, Pui, Ching-Hon, Downing, James R., Campana, Dario

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Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma von Chen, Xiang, Stewart, Elizabeth, Shelat, Anang A., Qu, Chunxu, Bahrami, Armita, Hatley, Mark, Wu, Gang, Bradley, Cori, McEvoy, Justina, Pappo, Alberto, Spunt, Sheri, Valentine, Marcus B., Valentine, Virginia, Krafcik, Fred, Lang, Walter H., Wierdl, Monika, Tsurkan, Lyudmila, Tolleman, Viktor, Federico, Sara M., Morton, Chris, Lu, Charles, Ding, Li, Easton, John, Rusch, Michael, Nagahawatte, Panduka, Wang, Jianmin, Parker, Matthew, Wei, Lei, Hedlund, Erin, Finkelstein, David, Edmonson, Michael, Shurtleff, Sheila, Boggs, Kristy, Mulder, Heather, Yergeau, Donald, Skapek, Steve, Hawkins, Douglas S., Ramirez, Nilsa, Potter, Philip M., Sandoval, John A., Davidoff, Andrew M., Mardis, Elaine R., Wilson, Richard K., Zhang, Jinghui, Downing, James R., Dyer, Michael A.

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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia von Coustan-Smith, Elaine, MS, Mullighan, Charles G, MD, Onciu, Mihaela, MD, Behm, Frederick G, Prof, Raimondi, Susana C, Prof, Pei, Deqing, MS, Cheng, Cheng, PhD, Su, Xiaoping, PhD, Rubnitz, Jeffrey E, MD, Basso, Giuseppe, Prof, Biondi, Andrea, Prof, Pui, Ching-Hon, Prof, Downing, James R, Prof, Campana, Dario, Prof

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Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study von Pui, Ching-Hon, Prof, Pei, Deqing, MS, Coustan-Smith, Elaine, MS, Jeha, Sima, Prof, Cheng, Cheng, Prof, Bowman, W Paul, MD, Sandlund, John T, Prof, Ribeiro, Raul C, Prof, Rubnitz, Jeffrey E, Prof, Inaba, Hiroto, MD PhD, Bhojwani, Deepa, MD, Gruber, Tanja A, MD PhD, Leung, Wing H, Prof, Downing, James R, Prof, Evans, William E, Prof, Relling, Mary V, Prof, Campana, Dario, Prof

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Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial von Rubnitz, Jeffrey E, Prof, Inaba, Hiroto, MD, Dahl, Gary, Prof, Ribeiro, Raul C, Prof, Bowman, W Paul, Prof, Taub, Jeffrey, MD, Pounds, Stanley, PhD, Razzouk, Bassem I, MD, Lacayo, Norman J, MD, Cao, Xueyuan, PhD, Meshinchi, Soheil, MD, Degar, Barbara, MD, Airewele, Gladstone, MD, Raimondi, Susana C, Prof, Onciu, Mihaela, MD, Coustan-Smith, Elaine, MS, Downing, James R, Prof, Leung, Wing, Prof, Pui, Ching-Hon, Prof, Campana, Dario, Prof

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Rearrangement of CRLF2 in B-progenitor– and Down syndrome–associated acute lymphoblastic leukemia von Mullighan, Charles G, Collins-Underwood, J Racquel, Phillips, Letha A A, Loudin, Michael G, Liu, Wei, Zhang, Jinghui, Ma, Jing, Coustan-Smith, Elaine, Harvey, Richard C, Willman, Cheryl L, Mikhail, Fady M, Meyer, Julia, Carroll, Andrew J, Williams, Richard T, Cheng, Jinjun, Heerema, Nyla A, Basso, Giuseppe, Pession, Andrea, Pui, Ching-Hon, Raimondi, Susana C, Hunger, Stephen P, Downing, James R, Carroll, William L, Rabin, Karen R

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