Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes von Monti, Remo, Rautenstrauch, Pia, Ghanbari, Mahsa, James, Alva Rani, Kirchler, Matthias, Ohler, Uwe, Konigorski, Stefan, Lippert, Christoph

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PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia von Bastian, Lorenz, Schroeder, Michael P., Eckert, Cornelia, Schlee, Cornelia, Tanchez, Jutta Ortiz, Kämpf, Sebastian, Wagner, Dimitrios L., Schulze, Veronika, Isaakidis, Konstandina, Lázaro-Navarro, Juan, Hänzelmann, Sonja, James, Alva Rani, Ekici, Arif, Burmeister, Thomas, Schwartz, Stefan, Schrappe, Martin, Horstmann, Martin, Vosberg, Sebastian, Krebs, Stefan, Blum, Helmut, Hecht, Jochen, Greif, Philipp A., Rieger, Michael A., Brüggemann, Monika, Gökbuget, Nicola, Neumann, Martin, Baldus, Claudia D.

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Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia von James, Alva Rani, Schroeder, Michael P, Neumann, Martin, Bastian, Lorenz, Eckert, Cornelia, Gökbuget, Nicola, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, Schwartz, Stefan, Burmeister, Thomas, von Stackelberg, Arend, Rieger, Michael A, Göllner, Stefanie, Horstman, Martin, Schrappe, Martin, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Akalin, Altuna, Baldus, Claudia D

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Author Correction: MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures von Mondal, Tanmoy, Subhash, Santhilal, Vaid, Roshan, Enroth, Stefan, Uday, Sireesha, Reinius, Björn, Mitra, Sanhita, Mohammed, Arif, James, Alva Rani, Hoberg, Emily, Moustakas, Aristidis, Gyllensten, Ulf, Jones, Steven J. M., Gustafsson, Claes M., Sims, Andrew H., Westerlund, Fredrik, Gorab, Eduardo, Kanduri, Chandrasekhar

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MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures von Mondal, Tanmoy, Subhash, Santhilal, Vaid, Roshan, Enroth, Stefan, Uday, Sireesha, Reinius, Björn, Mitra, Sanhita, Mohammed, Arif, James, Alva Rani, Hoberg, Emily, Moustakas, Aristidis, Gyllensten, Ulf, Jones, Steven J.M., Gustafsson, Claes M, Sims, Andrew H, Westerlund, Fredrik, Gorab, Eduardo, Kanduri, Chandrasekhar

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Long noncoding RNAs have pivotal roles in chemoresistance of acute myeloid leukemia von Izadirad, Mehrdad, Jafari, Leila, James, Alva Rani, Unfried, Juan Pablo, Wu, Zhuo-Xun, Chen, Zhe-Sheng

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Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures von Schroeder, Michael P., Bastian, Lorenz, Eckert, Cornelia, Gökbuget, Nicola, James, Alva Rani, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, Häupl, Björn, Baum, Katharina, Migueles Lozano, Oscar Arturo, Kouidri, Khouloud, Pan, Kuan-Ting, Urlaub, Henning, Schwartz, Stefan, Burmeister, Thomas, von Stackelberg, Arend, Hoelzer, Dieter, Pfeiffer, Heike, Rieger, Michael A., Göllner, Stefanie, Oellerich, Thomas, Horstman, Martin, Schrappe, Martin, Wolf, Jana, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Neumann, Martin, Baldus, Claudia D.

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LncRNAs signature defining major subtypes of B-cell acute lymphoblastic leukemia von James, Alva Rani

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Homocygous PAX5Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia von Bastian, Lorenz, Schroeder, Michael P, Eckert, Cornelia, Schlee, Cornelia, Tanchez, Jutta Ortiz, Kämpf, Sebastian, Wagner, Dimitrios L., Schulze, Veronika, Isaakidis, Konstandina, James, Alva Rani, Burmeister, Thomas, Schwartz, Stefan, Vosberg, Sebastian, Krebs, Stefan, Blum, Helmut, Hecht, Jochen, Greif, Philipp A., Rieger, Michael A., Brüggemann, Monika, Goekbuget, Nicola, Müller-Tidow, Carsten, Serve, Hubert, Neumann, Martin, Baldus, Claudia D.

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Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia von Neumann, Martin, Schroeder, Michael P, Bastian, Lorenz, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, James, Alva Rani, Fransecky, Lars R., Vosberg, Sebastian, Krebs, Stefan, Blum, Helmut, Schwartz, Stefan, Burmeister, Thomas, Hoelzer, Dieter, Greif, Philipp A., Brüggemann, Monika, Goekbuget, Nicola, Baldus, Claudia D.

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Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL von Bastian, Lorenz, Neumann, Martin, Gökbuget, Nicola, Schlee, Cornelia, Tanchez, Jutta Ortiz, Vosberg, Sebastian, James, Alva Rani, Schroeder, Michael P, Schwartz, Stefan, Hoelzer, Dieter, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Hecht, Jochen, Brüggemann, Monika, Greif, Philipp A., Baldus, Claudia D.

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Multi-Genomics of Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Reveals Three Distinct Genetic Clusters Characterized By Different Alterations von Schroeder, Michael P, Neumann, Martin, Eckert, Cornelia, Bastian, Lorenz, James, Alva Rani, Gökbuget, Nicola, Schlee, Cornelia, Ortiz Tanchez, Jutta, Isaakidis, Konstandina, Schwartz, Stefan, Burmeister, Thomas, Hoelzer, Dieter, Pfeiffer, Heike, Rieger, Michael A, Göllner, Stefanie, Oellerich, Thomas, Yepes, Diego, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Baldus, Claudia D.

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Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients von von der Heide, Eva, Vosberg, Sebastian, Neumann, Martin, Mochmann, Liliana H., Rani James, Alva, Ortiz Tanchez, Jutta, Schlee, Cornelia, Isaakidis, Konstandina, Luther, Marlene, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Hofmann, Wolf-Karsten, Greif, Philipp A, Baldus, Claudia D

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MEG3 long noncoding RNA regulates the TGF-[beta] pathway genes through formation of RNA-DNA triplex structures von Mondal, Tanmoy, Subhash, Santhilal, Vaid, Roshan, Enroth, Stefan, Uday, Sireesha, Reinius, Björn, Mitra, Sanhita, Mohammed, Arif, James, Alva Rani, Hoberg, Emily, Moustakas, Aristidis, Gyllensten, Ulf, Jones, Steven Jm, Gustafsson, Claes M, Sims, Andrew H, Westerlund, Fredrik, Gorab, Eduardo, Kanduri, Chandrasekhar

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MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures von Mondal, Tanmoy, Subhash, Santhilal, Vaid, Roshan, Enroth, Stefan, Uday, Sireesha, Reinius, Björn, Mitra, Sanhita, Mohammed, Arif, James, Alva Rani, Hoberg, Emily, Moustakas, Aristidis, Gyllensten, Ulf, Jones, Steven J M, Gustafsson, Claes M, Sims, Andrew H, Westerlund, Fredrik, Gorab, Eduardo, Kanduri, Chandrasekhar

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Additional file 5: of Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia von James, Alva Rani, Schroeder, Michael, Neumann, Martin, Bastian, Lorenz, Eckert, Cornelia, GĂśkbuget, Nicola, Tanchez, Jutta, Schlee, Cornelia, Konstandina Isaakidis, Schwartz, Stefan, Burmeister, Thomas, Stackelberg, Arend, Rieger, Michael, GĂśllner, Stefanie, Horstman, Martin, Schrappe, Martin, Kirschner-Schwabe, Renate, BrĂźggemann, Monika, MĂźller-Tidow, Carsten, Serve, Hubert, Altuna Akalin, Baldus, Claudia

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Additional file 4: of Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia von James, Alva Rani, Schroeder, Michael, Neumann, Martin, Bastian, Lorenz, Eckert, Cornelia, GĂśkbuget, Nicola, Tanchez, Jutta, Schlee, Cornelia, Konstandina Isaakidis, Schwartz, Stefan, Burmeister, Thomas, Stackelberg, Arend, Rieger, Michael, GĂśllner, Stefanie, Horstman, Martin, Schrappe, Martin, Kirschner-Schwabe, Renate, BrĂźggemann, Monika, MĂźller-Tidow, Carsten, Serve, Hubert, Altuna Akalin, Baldus, Claudia

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Additional file 3: of Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia von James, Alva Rani, Schroeder, Michael, Neumann, Martin, Bastian, Lorenz, Eckert, Cornelia, GĂśkbuget, Nicola, Tanchez, Jutta, Schlee, Cornelia, Konstandina Isaakidis, Schwartz, Stefan, Burmeister, Thomas, Stackelberg, Arend, Rieger, Michael, GĂśllner, Stefanie, Horstman, Martin, Schrappe, Martin, Kirschner-Schwabe, Renate, BrĂźggemann, Monika, MĂźller-Tidow, Carsten, Serve, Hubert, Altuna Akalin, Baldus, Claudia

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Additional file 1: of Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia von James, Alva Rani, Schroeder, Michael, Neumann, Martin, Bastian, Lorenz, Eckert, Cornelia, GĂśkbuget, Nicola, Tanchez, Jutta, Schlee, Cornelia, Konstandina Isaakidis, Schwartz, Stefan, Burmeister, Thomas, Stackelberg, Arend, Rieger, Michael, GĂśllner, Stefanie, Horstman, Martin, Schrappe, Martin, Kirschner-Schwabe, Renate, BrĂźggemann, Monika, MĂźller-Tidow, Carsten, Serve, Hubert, Altuna Akalin, Baldus, Claudia

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