Expression and lysosomal targeting of CLN7, a major facilitator superfamily transporter associated with variant late-infantile neuronal ceroid lipofuscinosis von Sharifi, A., Kousi, M., Sagné, C., Bellenchi, G.C., Morel, L., Darmon, M., Hůlková, H., Ruivo, R., Debacker, C., El Mestikawy, S., Elleder, M., Lehesjoki, A.-E., Jalanko, A., Gasnier, B., Kyttälä, A.

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Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries von Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.

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Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection von Zekavat, Seyedeh M., Lin, Shu-Hong, Bick, Alexander G., Liu, Aoxing, Paruchuri, Kaavya, Wang, Chen, Uddin, Md Mesbah, Ye, Yixuan, Yu, Zhaolong, Liu, Xiaoxi, Kamatani, Yoichiro, Bhattacharya, Romit, Pirruccello, James P., Pampana, Akhil, Loh, Po-Ru, Kohli, Puja, McCarroll, Steven A., Kiryluk, Krzysztof, Neale, Benjamin, Ionita-Laza, Iuliana, Engels, Eric A., Brown, Derek W., Smoller, Jordan W., Green, Robert, Karlson, Elizabeth W., Lebo, Matthew, Ellinor, Patrick T., Weiss, Scott T., Daly, Mark J., Terao, Chikashi, Zhao, Hongyu, Ebert, Benjamin L., Reilly, Muredach P., Ganna, Andrea, Machiela, Mitchell J., Genovese, Giulio, Natarajan, Pradeep

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Genetic architecture of human plasma lipidome and its link to cardiovascular disease von Tabassum, Rubina, Rämö, Joel T., Ripatti, Pietari, Koskela, Jukka T., Kurki, Mitja, Karjalainen, Juha, Palta, Priit, Hassan, Shabbeer, Nunez-Fontarnau, Javier, Kiiskinen, Tuomo T. J., Söderlund, Sanni, Matikainen, Niina, Gerl, Mathias J., Surma, Michal A., Klose, Christian, Stitziel, Nathan O., Laivuori, Hannele, Havulinna, Aki S., Service, Susan K., Salomaa, Veikko, Pirinen, Matti, Jauhiainen, Matti, Daly, Mark J., Freimer, Nelson B., Palotie, Aarno, Taskinen, Marja-Riitta, Simons, Kai, Ripatti, Samuli

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The role of polygenic risk and susceptibility genes in breast cancer over the course of life von Mars, Nina, Widén, Elisabeth, Kerminen, Sini, Meretoja, Tuomo, Pirinen, Matti, della Briotta Parolo, Pietro, Palta, Priit, Palotie, Aarno, Kaprio, Jaakko, Joensuu, Heikki, Daly, Mark, Ripatti, Samuli

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Biosynthesis and Intracellular Targeting of the CLN3 Protein Defective in Batten Disease von Järvelä, Irma, Sainio, Markku, Rantamäki, Terhi, Olkkonen, Vesa M., Carpén, Olli, Peltonen, Leena, Jalanko, Anu

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Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis von Hellsten, E., Vesa, J., Olkkonen, V. M., Jalanko, A., Peltonen, L.

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Liver-Kidney Transplantation to Cure Atypical Hemolytic Uremic Syndrome von SALAND, Jeffrey M, RUGGENENTI, Piero, REMUZZI, Giuseppe

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Mutant Mitochondrial Helicase Twinkle Causes Multiple mtDNA Deletions and a Late-Onset Mitochondrial Disease in Mice von Henna Tyynismaa, Katja Peltola Mjosund, Sjoerd Wanrooij, Ilse Lappalainen, Emil Ylikallio, Anu Jalanko, Johannes N. Spelbrink, Anders Paetau, Suomalainen, Anu

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A FinnGen pilot clinical recall study for Alzheimer’s disease von Julkunen, Valtteri, Schwarz, Claudia, Kalapudas, Juho, Hallikainen, Merja, Piironen, Aino-Kaisa, Mannermaa, Arto, Kujala, Hanna, Laitinen, Timo, Kosma, Veli-Matti, Paajanen, Teemu I., Kälviäinen, Reetta, Hiltunen, Mikko, Herukka, Sanna-Kaisa, Kärkkäinen, Sari, Kokkola, Tarja, Urjansson, Mia, Perola, Markus, Palotie, Aarno, Vuoksimaa, Eero, Runz, Heiko

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Molecular Genetics the Finnish Disease Heritage von Peltonen, Leena, Jalanko, Anu, Varilo, Teppo

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Bone marrow transplantation in young aspartylglucosaminuria mice: improved clearance of lysosomal storage in brain by using wild type as compared to heterozygote donors von Laine, M, Ahtiainen, L, Rapola, J, Richter, J, Jalanko, A

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Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number von Tyynismaa, Henna, Sembongi, Hiroshi, Bokori-Brown, Monika, Granycome, Caroline, Ashley, Neil, Poulton, Joanna, Jalanko, Anu, Spelbrink, Johannes N., Holt, Ian J., Suomalainen, Anu

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Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway von Luiro, Kaisu, Yliannala, Kristiina, Ahtiainen, Laura, Maunu, Heidi, Järvelä, Irma, Kyttälä, Aija, Jalanko, Anu

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Lysosomal localization of the neuronal ceroid lipofuscinosis CLN5 protein von Isosomppi, Juha, Vesa, Jouni, Jalanko, Anu, Peltonen, Leena

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Stress-Induced Expression of a Novel Variant of Human Fumarate Hydratase (FH) von LEHTONEN, HELI J., YLISAUKKO-OJA, SANNA K., KIURU, MAIJA, KARHU, AULI, LEHTONEN, RAINER, VANHARANTA, SAKARI, JALANKO, ANU, AALTONEN, LAURI A., LAUNONEN, VIRPI

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CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles : new clues to Batten disease von LUIRO, Kaisu, KOPRA, Outi, LEHTOVIRTA, Maarit, JALANKO, Anu

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Native and Complexed IGF-1: Biodistribution and Pharmacokinetics in Infantile Neuronal Ceroid Lipofuscinosis von Huhtala, Tuulia, Rytkönen, Jussi, Jalanko, Anu, Kaasalainen, Martti, Salonen, Jarno, Riikonen, Raili, Närvänen, Ale

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Palmitoyl protein thioesterase 1 is targeted to the axons in neurons von Ahtiainen, Laura, Van Diggelen, Otto P., Jalanko, Anu, Kopra, Outi

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AP-1 and AP-3 Facilitate Lysosomal Targeting of Batten Disease Protein CLN3 via Its Dileucine Motif von Kyttälä, Aija, Yliannala, Kristiina, Schu, Peter, Jalanko, Anu, Luzio, J. Paul

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