Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis von Soberanes, Saul, Misharin, Alexander V., Jairaman, Amit, Morales-Nebreda, Luisa, McQuattie-Pimentel, Alexandra C., Cho, Takugo, Hamanaka, Robert B., Meliton, Angelo Y., Reyfman, Paul A., Walter, James M., Chen, Ching-I, Chi, Monica, Chiu, Stephen, Gonzalez-Gonzalez, Francisco J., Antalek, Matthew, Abdala-Valencia, Hiam, Chiarella, Sergio E., Sun, Kaitlyn A., Woods, Parker S., Ghio, Andrew J., Jain, Manu, Perlman, Harris, Ridge, Karen M., Morimoto, Richard I., Sznajder, Jacob I., Balch, William E., Bhorade, Sangeeta M., Bharat, Ankit, Prakriya, Murali, Chandel, Navdeep S., Mutlu, Gökhan M., Budinger, G.R. Scott

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C103 OUTDOOR AIR POLLUTION: EPIDEMIOLOGY AND MECHANISMS: Metformin Inhibits Mitochondrial Ros Upstream Of Crac Channels In Alveolar Macrophages And Prevents Particulate Matter Air... von Soberanes, S, Misharin, A V, Jairaman, A, Chi, M, Chiarella, S E, Meliton, A, Anekalla, K Reddy, Gonzalez, F J, McQuattie-Pimentel, A, Piseaux, R, Perlman, H, Chandel, N S, Prakriya, M, Mutlu, G M, Budinger, G S

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D96 DAMAGING EFFECTS OF INHALED PARTICULATES: Metformin Attenuates Particulate Matter Air Pollution Induced Thrombosis By Inhibiting Mitochondrial Ros Upstream Of Crac Channels In... von Soberanes, S, Jairaman, A, Chi, M, Meliton, A Y, Cho, J, Gonzalez-Gonzalez, F J, Mc Quattie-Pimentel, A C, Piseaux, R, Weinberg, S, Perlman, H R, Chandel, N S, Misharin, A V, Prakriya, M, Mutlu, G M, Budinger, G

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Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing von Atcha, Hamza, Jairaman, Amit, Holt, Jesse R., Meli, Vijaykumar S., Nagalla, Raji R., Veerasubramanian, Praveen Krishna, Brumm, Kyle T., Lim, Huy E., Othy, Shivashankar, Cahalan, Michael D., Pathak, Medha M., Liu, Wendy F.

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Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease von McQuade, Amanda, Kang, You Jung, Hasselmann, Jonathan, Jairaman, Amit, Sotelo, Alexandra, Coburn, Morgan, Shabestari, Sepideh Kiani, Chadarevian, Jean Paul, Fote, Gianna, Tu, Christina H., Danhash, Emma, Silva, Jorge, Martinez, Eric, Cotman, Carl, Prieto, G. Aleph, Thompson, Leslie M., Steffan, Joan S., Smith, Ian, Davtyan, Hayk, Cahalan, Michael, Cho, Hansang, Blurton-Jones, Mathew

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TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia von Jairaman, Amit, McQuade, Amanda, Granzotto, Alberto, Kang, You Jung, Chadarevian, Jean Paul, Gandhi, Sunil, Parker, Ian, Smith, Ian, Cho, Hansang, Sensi, Stefano L, Othy, Shivashankar, Blurton-Jones, Mathew, Cahalan, Michael D

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Molecular pharmacology of store-operated CRAC channels von Jairaman, Amit, Prakriya, Murali

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T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse von Dong, Tobias X, Othy, Shivashankar, Jairaman, Amit, Skupsky, Jonathan, Zavala, Angel, Parker, Ian, Dynes, Joseph L, Cahalan, Michael D

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The C‐ and N‐terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels von McNally, Beth A., Somasundaram, Agila, Jairaman, Amit, Yamashita, Megumi, Prakriya, Murali

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Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels von Mungai, Paul T., Waypa, Gregory B., Jairaman, Amit, Prakriya, Murali, Dokic, Danijela, Ball, Molly K., Schumacker, Paul T.

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Store-Operated Ca2+ Release-Activated Ca2+ Channels Regulate PAR2-Activated Ca2+ Signaling and Cytokine Production in Airway Epithelial Cells von Jairaman, Amit, Yamashita, Megumi, Schleimer, Robert P, Prakriya, Murali

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Allergens stimulate store-operated calcium entry and cytokine production in airway epithelial cells von Jairaman, Amit, Maguire, Chelsea H., Schleimer, Robert P., Prakriya, Murali

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Propugnating Effect of Bark of Rhizophora mucronata Against Different Toxicants Viz Carbon Tetrachloride, Ethanol and Paracetamol on HepG 2 Cell Lines von Jairaman, Chitra, Yacoob, Syed Ali Mohamed, Venkatraman, Anuradha, Nagarajan, Yogananth, Murugesan, Gnanadesigan

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Ion channel mediated mechanotransduction in immune cells von Atcha, Hamza, Jairaman, Amit, Evans, Elizabeth L., Pathak, Medha M., Cahalan, Michael D., Liu, Wendy F.

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Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation von Maus, Mate, Jairaman, Amit, Stathopulos, Peter B., Muik, Martin, Fahrner, Marc, Weidinger, Carl, Benson, Melina, Fuchs, Sebastian, Ehl, Stephan, Romanin, Christoph, Ikura, Mitsuhiko, Prakriya, Murali, Feske, Stefan

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Clinical and epidemiological characteristics of patients seeking COVID-19 testing in a private centre in Malaysia: Is there a role for private healthcare in battling the outbreak? von Chow, Yock Ping, Chin, Brenda Huey Zien, Loo, Jin Ming, Moorthy, Loshini R., Jairaman, Jamuna, Tan, Lian Huat, Tay, Wendy Wan Ying

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Calcium Imaging in T Lymphocytes: a Protocol for Use with Genetically Encoded or Chemical Ca 2+ Indicators von Jairaman, Amit, Cahalan, Michael D

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Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease von McQuade, Amanda, Kang, You Jung, Hasselmann, Jonathan, Jairaman, Amit, Sotelo, Alexandra, Coburn, Morgan, Shabestari, Sepideh Kiani, Chadarevian, Jean Paul, Fote, Gianna, Tu, Christina H., Danhash, Emma, Silva, Jorge, Martinez, Eric, Cotman, Carl, Prieto, G. Aleph, Thompson, Leslie M., Steffan, Joan S., Smith, Ian, Davtyan, Hayk, Cahalan, Michael, Cho, Hansang, Blurton-Jones, Mathew

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Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling von Sena, Laura A., Li, Sha, Jairaman, Amit, Prakriya, Murali, Ezponda, Teresa, Hildeman, David A., Wang, Chyung-Ru, Schumacker, Paul T., Licht, Jonathan D., Perlman, Harris, Bryce, Paul J., Chandel, Navdeep S.

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Differential regulation of ATP- and UTP-evoked PGE2 and IL-6 production from human airway epithelial cells von Kountz, Timothy S., Jairaman, Amit, Kountz, Candace D., Stauderman, Kenneth A., Schleimer, Robert P., Prakriya, Murali

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